Immunomodulatory activity of Tityus serrulatus scorpion venom on human T lymphocytes. [PDF]
\ud \ud Background\ud \ud Tityus serrulatus scorpion venom (TsV) contains toxins that act on K+ and Na+ channels and account for the venom’s toxic effects.
Casella-Martins A+9 more
europepmc +12 more sources
Tityus serrulatus Scorpion Venom Induces Apoptosis in Cervical Cancer Cell Lines. [PDF]
Cervical cancer (CC) is classified as the fourth most common type of cancer in women worldwide and remains a serious public health problem in many underdeveloped countries. Human papillomavirus (HPV), mainly types 16 and 18, has been established as a precursory etiologic agent for this type of cancer.
Bernardes-Oliveira E+8 more
europepmc +2 more sources
Inhibition of Tityus serrulatus venom hyaluronidase affects venom biodistribution. [PDF]
The hyaluronidase enzyme is generally known as a spreading factor in animal venoms. Although its activity has been demonstrated in several organisms, a deeper knowledge about hyaluronidase and the venom spreading process from the bite/sting site until its elimination from the victim's body is still in need.
Oliveira-Mendes BBR+10 more
europepmc +5 more sources
Scorpion Venom and the Inflammatory Response [PDF]
Scorpion venoms consist of a complex of several toxins that exhibit a wide range of biological properties and actions, as well as chemical compositions, toxicity, and pharmacokinetic and pharmacodynamic characteristics.
Petricevich, Vera L.
core +3 more sources
Selected to survive and kill: Tityus serrulatus, the Brazilian yellow scorpion. [PDF]
Annually, more than 1.2 million scorpion stings and more than 3,000 deaths occur worldwide. Tityus serrulatus Lutz and Mello, 1922 (Scorpiones, Buthidae) is the most medically relevant species in Brazil where it is spreading rapidly and causing over 90,000 cases of envenomation yearly. We monitored T. serrulatus longevity and ability to reproduce under
Pimenta RJG+6 more
europepmc +5 more sources
Electrophysiological Characterization of the Antarease Metalloprotease from Tityus serrulatus Venom. [PDF]
Scorpions are among the oldest venomous living organisms and the family Buthidae is the largest and most medically relevant one. Scorpion venoms include many toxic peptides, but recently, a metalloprotease from Tityus serrulatus called antarease was reported to be capable of cleaving VAMP2, a protein involved in the neuroparalytic syndromes of tetanus ...
Zornetta I+6 more
europepmc +6 more sources
Redefinition of the identity and phylogenetic position of Tityus trivittatus Kraepelin 1898, and description of Tityus carrilloi n. sp. (Scorpiones; Buthidae), the most medically important scorpion of southern South America. [PDF]
Redefinición de la identidad y posición filogenética de Tityus trivittatus Kraepelin 1898, y descripción de Tityus carrilloi n. sp. (Scorpiones; Buthidae), la especie de mayor importancia médica del sur de Sudamérica. Tityus trivittatus es considerada la
Adolfo Borges
exaly +3 more sources
The dynamics of cytokine d nitric oxide secretion in mice injected with Tityus serrulatus scorpion venom. [PDF]
AIMS: The effects of Tityus serrulatus venom (TSV) were analysed with respect to the susceptibility of four isogenic mouse, the symptoms following injection of venom and the inflammatory mediators in an experimental model of severe envenomation induced ...
Petricevich, Vera L, Peña, Carlos F
core +4 more sources
Neutralizing effects of Mimosa tenuiflora extracts against inflammation caused by Tityus serrulatus scorpion venom. [PDF]
Scorpion bite represents a significant and serious public health problem in certain regions of Brazil, as well as in other parts of the world. Inflammatory mediators are thought to be involved in the systemic and local immune response induced by Tityus serrulatus scorpion envenomation.
Bitencourt MA+7 more
europepmc +2 more sources
Identification and Phylogenetic Analysis of Tityus pachyurus and Tityus obscurus Novel Putative Na+-Channel Scorpion Toxins [PDF]
Background: Colombia and Brazil are affected by severe cases of scorpionism. In Colombia the most dangerous accidents are caused by Tityus pachyurus that is widely distributed around this country.
Verónica Quintero-hernández+2 more
exaly +8 more sources