Results 171 to 180 of about 7,680 (212)

Effective Tityus serrulatus anti-venom produced using the Ts1 component

Toxicon, 2008
Scorpion stings are a public health problem in Brazil, with most incidents involving the species Tityus serrulatus. Some T. serrulatus toxins may act as immunogens for the production of a specific anti-venom, but many of the component toxins remain poorly characterized. Here, we describe the immunological characteristics of the toxin Ts1 (also known as
T M, Mendes, F, Dias, C C R, Horta, I F, Pena, E C, Arantes, E, Kalapothakis   +5 more
openaire   +2 more sources

Tityus serrulatus Hypotensins: A new family of peptides from scorpion venom

Biochemical and Biophysical Research Communications, 2008
Using a proteomic approach, a new structural family of peptides was put in evidence in the venom of the yellow scorpion Tityus serrulatus. Tityus serrulatus Hypotensins (TsHpt) are random-coiled linear peptides and have a similar bradykinin-potentiating peptide (BPP) amino acid signature.
Thiago Verano-Braga, Adriano M C Pimenta
exaly   +3 more sources

Synergistic action of toxins from Tityus serrulatus scorpion venom

Toxicon
E. Arantes
semanticscholar   +2 more sources

A comparative study of pathophysiological alterations in scorpionism induced by Tityus serrulatus and Tityus bahiensis venoms

Toxicon, 2018
Scorpionism is a relevant public health problem in several countries in tropical and subtropical regions. In Brazil, Tityus serrulatus sting can induce acute lung injury in part as a consequence of inflammation. Despite the occurrence of other scorpions of Tityus genus in Brazilian scorpiofauna, the knowledge regarding pulmonary alterations is related ...
Jackson G. Miyamoto, Fabio B. Andrade, Camila R. Ferraz, Denise M. Cândido, Irene Knysak, Émerson J. Venancio, Waldiceu A. Verri, Maristella A. Landgraf, Richardt G. Landgraf, Fábio H. Kwasniewski   +9 more
openaire   +2 more sources

Activity pattern of Tityus serrulatus (Scorpiones: Buthidae) in an urban area in the state of São Paulo, Brazil

Medical and Veterinary Entomology
Tityus serrulatus Lutz & Mello (Scorpiones: Buthidae) is a scorpion endemic to Brazil adapted to synanthropic life, colonising and proliferating in the most populous urban areas in the country. Here, we evaluated its activity pattern in an urban cemetery
José Brites-Neto, J. N. G. Willmer, A. Delciellos   +2 more
semanticscholar   +1 more source

Lung oedema induced by Tityus serrulatus scorpion venom in the rat

Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology, 1997
The effects of drugs were investigated on the induction of acute lung oedema by scorpion Tityus serrulatus venom in male Wistar rats (200-230 g) anaesthetized with sodium pentobarbital (40 mg/kg, i.p.). Intravenous (i.v.) injection of scorpion venom (0.5 mg/kg) into 12 rats induced arterial hypertension and severe lung oedema, whereas i.v. injection of
I M, De Matos, O A, Rocha, R, Leite, L, Freire-Maia   +3 more
openaire   +2 more sources

Acid-base balance following Tityus serrulatus scorpion envenoming in anaesthetized rats

Toxicon, 2000
In the present work the pH and arterial blood gases were measured in fasted and fed male albino rats, weighing 297 +/- 13 g, anaesthetized with urethane (1.4 g/kg, i.p.) before and after injection of T1 fraction from Titys serrulatus scorpion venom, during 60 min.
M, de Mônico Magalhães, V L, Garbacio, M B, de Almeida, A C, Braz, T, Moraes-Santos, L, Freire-Maia, J R, Cunha-Melo   +6 more
openaire   +2 more sources

Behavioural and electroencephalographic effects of Tityus serrulatus scorpion venom in rats

Toxicon, 1993
This study was designed to investigate the convulsant effects of T. serrulatus scorpion venom in rats. Pretreatment of rats with venom increased the minimum convulsant dose of picrotoxin, impaired convulsion generalization and displaced to the left the dose-response curve for picrotoxin.
M R, Sandoval, V A, Dorce
openaire   +2 more sources

Isolation of a Bradykinin-Potentiating Factor from Scorpion Tityus Serrulatus Venom

1992
A bradykinin-potentiating factor was isolated and characterized from the scorpion Tityus serrulatus venom by chromatographic techniques and reverse phase followed by biological assays. This factor showed to be able to potentiate the contractile activity of the isolated guinea-pig ileum, inhibited the angiotensin-converting enzyme and potentiated the ...
L A, Ferreira, O B, Henriques
openaire   +2 more sources

Peripheral Effects ofTityus serrulatusScorpion Venom

Journal of Toxicology: Toxin Reviews, 1995
AbstractIn this review we describe the peripheral effects induced by Tityus serrulatus scorpion venom and two of the most important toxins-tityustoxin and toxin Ts-γ purified from the crude venom. The complex cardiac arrhythmias elicited by the venom or the toxins were explained by the release of catecholamines and acetylcholine. In isolated rat atria,
openaire   +1 more source