Results 21 to 30 of about 7,680 (212)

New Insights into the Hypotensins from Tityus serrulatus Venom: Pro-Inflammatory and Vasopeptidases Modulation Activities. [PDF]

Toxins (Basel), 2021
The Tityus serrulatus scorpion is considered the most dangerous of the Brazilian fauna due to the severe clinical manifestations in injured victims. Despite being abundant components of the venom, few linear peptides have been characterized so far, such ...
Duzzi B, Silva CCF, Kodama RT, Cajado-Carvalho D, Squaiella-Baptistão CC, Portaro FCV.   +5 more
europepmc   +2 more sources

Unveiling Tst3, a Multi-Target Gating Modifier Scorpion α Toxin from <i>Tityus stigmurus</i> Venom of Northeast Brazil: Evaluation and Comparison with Well-Studied Ts3 Toxin of <i>Tityus serrulatus</i>. [PDF]

Toxins (Basel)
Studies on the interaction sites of peptide toxins and ion channels typically involve site-directed mutations in toxins. However, natural mutant toxins exist among them, offering insights into how the evolutionary process has conserved crucial sequences ...
Tibery DV, Nunes JAA, da Mata DO, Menezes LFS, de Souza ACB, Fernandes-Pedrosa MF, Treptow W, Schwartz EF.   +7 more
europepmc   +2 more sources

Proteome of fraction from Tityus serrulatus venom reveals new enzymes and toxins. [PDF]

J Venom Anim Toxins Incl Trop Dis, 2019
Background: Tityus serrulatus venom (Ts venom) is a complex mixture of several compounds with biotechnological and therapeutical potentials, which highlights the importance of the identification and characterization of these components.
Amorim FG, Longhim HT, Cologna CT, Degueldre M, Pauw E, Quinton L, Arantes EC.   +6 more
europepmc   +2 more sources

Self-Assembled Cationic-Covered Nanoemulsion as A Novel Biocompatible Immunoadjuvant for Antiserum Production Against Tityus serrulatus Scorpion Venom. [PDF]

Pharmaceutics, 2020
This study assesses the efficacy of different nanoemulsion formulations as new and innovative adjuvants for improving the in vivo immunization against the Tityus serrulatus scorpion venom.
Medeiros ASA, Torres-Rêgo M, Lacerda AF, Rocha HAO, Egito ESTD, Cornélio AM, Tambourgi DV, Fernandes-Pedrosa MF, da Silva-Júnior AA.   +8 more
europepmc   +2 more sources

Tityus serrulatus Scorpion Venom: In Vitro Tests and Their Correlation with In Vivo Lethal Dose Assay [PDF]

Toxins, 2017
Scorpion stings are the main cause of human envenomation in Brazil and, for the treatment of victims, the World Health Organization (WHO) recommends the use of antivenoms.
Daniela Cajado-Carvalho, Juliana Galvão, Alexandre K. Kuniyoshi, Patrícia dos Santos Carneiro, Adriana Franco Paes Leme, Bianca Alves Pauletti, Eliana Blini Marengo, Fernanda V. Portaro   +7 more
doaj   +2 more sources

Purification and Biochemical Characterization of TsMS 3 and TsMS 4: Neuropeptide-Degrading Metallopeptidases in the Tityus serrulatus Venom. [PDF]

Toxins (Basel), 2019
Although omics studies have indicated presence of proteases on the Tityus serrulatus venom (TsV), little is known about the function of these molecules.
Cajado-Carvalho D, da Silva CCF, Kodama RT, Mariano DOC, Pimenta DC, Duzzi B, Kuniyoshi AK, Portaro FV.   +7 more
europepmc   +2 more sources

Novos registros georeferenciados de Tityus serrulatus Lutz & Mello, 1922 (Scorpiones, Buthidae) para o estado do Mato Grosso, centro-oeste do Brasil

Entomological Communications
We present additional records of Tityus serrulatus Lutz & Mello, 1922 (Scorpiones: Buthidae) for the state of Mato Grosso, midwestern Brazil. The record of this scorpion species, which can cause mild to severe envenomation, significantly contributes to ...
Jessé M. Ribeiro Junior, Pablo M. Pazóti, Marielle C. Schneider, Marcos A. Carvalho, Christine Strüssmann   +4 more
doaj   +2 more sources

Profiling the Linear Peptides of Venom from the Brazilian Scorpion Tityus serrulatus: Structural and Functional Characterization

Journal of Natural Products
Scorpion venoms are a rich source of bioactive peptides, most of which are neurotoxic, with 30 to 70 amino acid residues in their sequences. There are a scarcity of reports in the literature concerning the short linear peptides found in scorpion venoms ...
Nathalia Baptista Días, Bibiana Monson de Souza, Fernanda Cid-Alda, Valquíria Abrão Coronado Dorce, Fernando Kamimura Cocchi, Mário Sérgio Palma   +5 more
openalex   +3 more sources

Description of the male of Tityus kuryi Lourenço, 1997 and notes about males of Tityus stigmurus (Thorell, 1877) and Tityus serrulatus Lutz & Mello, 1922 (Scorpiones, Buthidae) [PDF]

ZooKeys, 2014
The male of Tityus kuryi Lourenço, 1997 is described for the first time. Despite being very similar to the female, the male presents more robust metasomal segments. Additionally, the distribution of the sexual populations of another two species of
Maria Dulcineia dos Santos, Tiago Jordão Porto, Rejâne Maria Lira da Silva, Tania Brazil   +3 more
doaj   +2 more sources

Experimental Tityus serrulatus scorpion envenomation: age- and sex-related differences in symptoms and mortality in mice [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2011
Among the various methods for evaluating animal venom toxicity, the calculation of the median lethal dose (LD50) is the most widely used. Although different protocols can be used to calculate the LD50, the source of the venom and the method of extraction,
Pucca MB, Roncolato EC, Campos LB, Fernandes FS, Mendes GR, Bertolini TB, Cerni FA, Barbosa JE   +7 more
doaj   +2 more sources