Results 11 to 20 of about 727 (176)
The CNS Meninges and the Synovial Joint: Parallel Immunological Structures in Autoimmune Disease. [PDF]
BioessaysThe meninges and synovium share multiple functional and structural characteristics and act as specialized immunological barriers. In MS and RA, both can host tertiary lymphoid organs (TLOs) and CD4+ Tph cells. We highlight how these features sustain compartmentalized inflammation and explore a possible role for EBV in their formation and persistence ...
Fazazi MR, Rangachari M.
europepmc +2 more sources
Zwei neue Inschriften aus dem Theatertempel von Tlos
Gephyra, 2023 This article presents the theatre temple of Tlos and two inscriptions carved on the walls of this temple. The temple was built on the central axis of the summa cavea of the Tlos theatre. The façade of the temple faces east.
Taner Korkut +2 more
doaj +1 more source
Investigating mammary glands of lactating goats for the presence of tertiary lymphoid organs
Frontiers in Immunology, 2022 Ectopic tertiary lymphoid organs (TLOs) have been identified in many organs, such as the lungs, nasal cavities, and kidneys of both mice and humans. Although lymphocyte aggregates have been observed in the mammary glands of ruminants, the details remain ...
Yusaku Tsugami +4 more
doaj +1 more source
Immuno, 2021 IgG4-related disease (IgG4-RD) is a fibro-inflammatory disease characterized by elevated serum IgG4 levels and massive infiltration of IgG4+plasma cells.
Mitsuhiro Akiyama, Yuko Kaneko
doaj +1 more source
Chronic Inflammation: A Common Promoter in Tertiary Lymphoid Organ Neogenesis
Frontiers in Immunology, 2019 Tertiary lymphoid organs (TLOs) frequently develop locally in adults in response to non-resolving inflammation. Chronic inflammation leads to the differentiation of stromal fibroblast cells toward lymphoid tissue organizer-like cells, which interact with
Shanshan Luo +7 more
doaj +1 more source
Tertiary Lymphoid Organs in Cancer Immunology: Mechanisms and the New Strategy for Immunotherapy
Frontiers in Immunology, 2019 The immune system plays pivotal roles in the occurrence and progression of cancers. As blockade of immune-checkpoint has been proven effective at improving anti-tumor immune response in multiple tumor types, the tumor immunotherapy still faces many ...
Liangbin Lin +3 more
doaj +1 more source
Frontiers in Immunology, 2016 High endothelial venules (HEVs) and lymphatic vessels (LVs) are essential for the function of the immune system, by providing communication between the body and lymph nodes (LNs), specialized sites of antigen presentation and recognition.
Nancy H Ruddle
doaj +1 more source
Engineering Adaptive Immunity in 3D: A Patient-Specific Lymphoid Model Using Stromal Networks and Peripheral Blood Mononuclear Cells. [PDF]
Adv Sci (Weinh)This study presents a 3D lymphoid tissue model engineered from adipose‐derived stem cells differentiated into fibroblastic reticular cell–like networks and co‐cultured with immune cells. The engineered system successfully generates antigen‐specific antibodies and cytokine responses, providing a platform for studying adaptive immunity, vaccine efficacy,
ElGindi M, Karaman S, Teo J.
europepmc +2 more sources
Teaching & Learning Inquiry: The ISSOTL Journal, 2015 This paper uses a trial audit of history programs undertaken in 2011-2012 to explore issues surrounding the attainment of Threshold Learning Outcomes (TLOs) in an emerging Australian national standards environment for the discipline of history. The audit
Sean Brawley +6 more
doaj +1 more source
The Location of Mount Masa on the Northern Border of Hellenistic Lycia
Gephyra, 2020 A mount called Masa is mentioned in an inscription from the Letoon (Rousset 2010) and in the foedus (treaty) between Caesar and Lycia (Mitchell 2005), as northern border of Hellenistic Lycia. The inscription from the Letoon, which dates from sometime 160-
Fatih ONUR
doaj +1 more source