Results 211 to 220 of about 13,006,177 (289)

When Explant Surprises: Management and Outcomes of Hepatocellular Carcinoma Beyond Milan Criteria Discovered Post‐Transplant‐ A Narrative Review of Literature

Journal of Surgical Oncology, EarlyView.
ABSTRACT Liver transplantation (LT) is the definitive treatment for early hepatocellular carcinoma (HCC), based on established criteria. Pre‐transplant imaging occasionally underestimates the tumor burden or biological aggressiveness, leading to explant pathology that exceeds the projection criteria, such as Milan.
Serkan Sucu, Brian Longbottom, Hassan Aziz   +2 more
wiley   +1 more source

Catalytic Site Inhibitors of Group 1 Allergens Prevent Toll-like Receptor (TLR)4- and TLR1/2-Dependent Innate Responses in Keratinocytes and Airway Epithelial Cells Exposed to House Dust Mite Allergenic Extract. [PDF]

ACS Pharmacol Transl Sci
Zhang J, Chen J, Ng WH, Saberi-Movahed AS, Rathore Z, Sayed N, George K, Sequeira D, Garrod D, Robinson C.   +9 more
europepmc   +1 more source

Superior patient‐reported clinical outcomes after patient‐individual total knee arthroplasty compared with off‐the‐shelf robotic‐assisted total knee arthroplasty in valgus knee phenotypes

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To compare early patient‐reported clinical outcomes of patient‐individual total knee arthroplasty (TKA) with individualized trochlear design versus robotic‐assisted TKA using off‐the‐shelf implants in patients with valgus knee phenotypes and pronounced femoral valgus (lateral distal femoral angle [LDFA] < 85°) at 3 and 12 months ...
Lars‐Rene Tuecking, Peter Savov, Mara Hold, Ricarda Stauss, Henning Windhagen, Max Ettinger   +5 more
wiley   +1 more source

Lactiplantibacillus plantarum FRT4 protects against fatty liver hemorrhage syndrome: regulating gut microbiota and FoxO/TLR-4/NF-κB signaling pathway in laying hens. [PDF]

Microbiome
Li D, Meng K, Liu G, Wen Z, Han Y, Liu W, Xu X, Song L, Cai H, Yang P.   +9 more
europepmc   +1 more source

Reduced length of stay and improved perioperative outcomes in robotic‐arm‐assisted TKA: A real‐world evidence study of 63,931 cases from German hospitals

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Robotic‐arm‐assisted surgery is increasingly used in orthopaedics due to its potential clinical benefits. This real‐world data analysis evaluated the impact of image‐based, robotic‐arm‐assisted total knee arthroplasty (raTKA) over non‐robotic‐arm‐assisted total knee arthroplasty (nraTKA) on perioperative outcomes in Germany based on a ...
Lars‐Rene Tuecking, Marco Ezechieli, Christoph Barkhausen, Christian Hendrich, Lea Charlotte Wienholt, Christoph Pross, Rüdiger von Eisenhart‐Rothe, Henning Windhagen   +7 more
wiley   +1 more source

Coenzyme Q10 alleviates AlCl₃ and D-galactose induced Alzheimer via modulating oxidative burden and TLR-4/MAPK pathways and regulation microRNA in rat brain. [PDF]

Toxicol Res (Camb)
Nawar NF, Beltagy DM, Tousson E, El-Keey MM, Mohamed TM.   +4 more
europepmc   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Anti-inflammatory effect of nestorone in a lipopolysaccharide-induced acute lung injury model through regulation of the TLR-4/Myd88/NF-κB signaling pathway. [PDF]

Inflammopharmacology
Ma A, Zhou J, Zou H, Yuan L, Zhong R, Zhu Y, Gao C.   +6 more
europepmc   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

The Gut–Brain Axis in Parkinson's Disease: From Clinical Observation toward Mechanism‐Based Precision Medicine

Movement Disorders, EarlyView.
Abstract Gastrointestinal dysfunction is increasingly recognized as a core feature of Parkinson's disease (PD), affecting quality of life, nutrition, medication response, and potentially the earliest stages of pathogenesis. This perspective traces the evolution of the gut from a neglected source of non‐motor symptoms to a central component of ...
Filip Scheperjans, Per Borghammer, Ronald F. Pfeiffer, Silke Appel‐Cresswell, Ali Keshavarzian   +4 more
wiley   +1 more source