Results 1 to 10 of about 141,965 (208)

Randomized controlled trial of vitamin d supplementation on toll-like receptor-2 (tlr-2) and toll-like receptor-4 (tlr-4) in tuberculosis spondylitis patients [PDF]

Journal of Orthopaedic Surgery and Research, 2023
Background Tuberculosis spondylitis accounts for approximately 50% of all cases of skeletal tuberculosis. Vitamin D plays a role in the immune system. Vitamin D helps in the activation of TLR-2 and TLR-4, which play a role in the process of tuberculosis ...
Jainal Arifin, Muhammad Nasrum Massi, Karya Triko Biakto, Agussalim Bukhari, Zairin Noor, Muhammad Phetrus Johan   +5 more
doaj   +2 more sources

Comparative analysis of TNF-α, TLR-2, and TLR-4 in GCF before and after periodontal therapy [PDF]

Brazilian Oral Research
Periodontitis is a chronic inflammatory disease characterized by progressive destruction of tooth-supporting tissues, primarily driven by a dysregulated host immune response to subgingival biofilms.
Mithat TERZI, Fatma ALTIPARMAK, Fatma Ucan YARKAC   +2 more
doaj   +3 more sources

Fonsecaeapedrosoi Conidia and Hyphae Activate Neutrophils Distinctly: Requirement of TLR-2 and TLR-4 in Neutrophil Effector Functions [PDF]

Frontiers in Immunology, 2020
Chromoblastomycosis is a chronic and progressive subcutaneous mycosis caused mainly by the fungus Fonsecaea pedrosoi. The infection is characterized by erythematous papules and histological sections demonstrating an external layer of fibrous tissue and ...
Leandro Carvalho Dantas Breda, Leandro Carvalho Dantas Breda, Cristiane Naffah de Souza Breda, José Roberto Fogaça de Almeida, Larissa Neves Monteiro Paulo, Grasielle Pereira Jannuzzi, Isabela de Godoy Menezes, Renata Chaves Albuquerque, Niels Olsen Saraiva Câmara, Karen Spadari Ferreira, Sandro Rogério de Almeida, Sandro Rogério de Almeida   +11 more
doaj   +2 more sources

CP91110P: A Computationally Designed Multi-Epitope Vaccine Candidate for Tuberculosis via TLR-2/4 Synergistic Immunomodulation [PDF]

Biology
Background: Tuberculosis (TB) remains a global health priority, with current interventions like the Bacille Calmette–Guérin (BCG) vaccine lacking efficacy against latent infection and drug-resistant strains.
Yajing An, Syed Luqman Ali, Yanhua Liu, Aigul Abduldayeva, Ruizi Ni, Yufeng Li, Mingming Zhang, Yuan Tian, Lina Jiang, Wenping Gong   +9 more
doaj   +2 more sources

Effects of toll like receptor 4 (TLR4) and toll like receptor 2 (TLR 2) gene polymorphisms on clinical outcomes in acute non-biliary pancreatitis patients [PDF]

Frontiers in Immunology
IntroductionIn this retrospective study, it was aimed to evaluate effects of Toll Like Receptor 4 (TLR4) and Toll Like Receptor 2 (TLR 2) gene polymorphisms on clinical outcomes in acute non-biliary pancreatitis patients.MethodsA total of 108 acute non ...
Ender Anılır, Filiz Özen, İbrahim Halil Yıldırım   +2 more
doaj   +2 more sources

Hyperresponsiveness of Corticoid-Resistant Th17/Tc-17 Cells to TLR-2 and TLR-4 Ligands is a Feature of Multiple Sclerosis Patients at Higher Risk of Therapy Failure [PDF]

Journal of Inflammation Research
Joana Hygino,1,* Marisa C Sales,2,* Priscila M Sacramento,1 Taissa M Kasahara,3 Júlio César Costa da Silva,3 Rafaela Bilhão,3 Regis M Andrade,4 Cláudia Cristina Ferreira Vasconcelos,1 Cleonice AM Bento1,3– 5 1Post-Graduate Program in Neurology ...
Hygino J, Sales MC, Sacramento PM, Kasahara TM, da Silva JCC, Bilhão R, Andrade RM, Vasconcelos CCF, Bento CA   +8 more
doaj   +2 more sources

Differential profiles of soluble and cellular toll like receptor (TLR)-2 and 4 in chronic periodontitis. [PDF]

PLoS ONE, 2018
Chronic periodontitis is a common inflammatory disease initiated by a complex microbial biofilm and mediated by the host response causing destruction of the supporting tissues of the teeth. Host recognition of pathogens is mediated by toll-like receptors
Hawra AlQallaf, Yusuke Hamada, Steven Blanchard, Daniel Shin, Richard Gregory, Mythily Srinivasan   +5 more
doaj   +2 more sources

Analysis of Expression and Localization of TLR-2 by Immunofluorescent Technique in Healthy and Inflammed Oral Tissues [PDF]

Journal of Clinical and Diagnostic Research, 2013
Introduction: Toll-like receptors (TLRs) are an important component of immune system. Among them, TLR-2 plays a dominant role in the oral tissues in initiating inflammation in chronic periodontitis.
Romaldin S. D’souza, Kishore G. Bhat, D. Sailaja, Deepa V. Babji, Tushar K. Bandiwadekar, Ramanand M. Katgalkar   +5 more
doaj   +1 more source

Influence of genetic variability in toll-like receptors (TLR 2, TLR 4, and TLR 9) on human immunodeficiency virus-1 disease progression

International Journal of Mycobacteriology, 2023
Background: It has been demonstrated that toll-like receptors (TLR2), TLR4, and TLR9 which were initially known for recognizing bacterial products are involved in the detection of viral components.
Gaurav Kaushik, Richa Vashishtha
doaj   +1 more source

Peculiarities of TLR-2 (Arg753Gln) and TLR-4 (Asp299Gly) polymorphism prevalence in patients with acute brucellosis with cardiovascular lesions

Journal of Education, Health and Sport, 2018
Currently, there are single data on the relationship between TLR-2 polymorphisms (Arg753Gln) and TLR-4 (Asp299Gly) polymorphisms and susceptibility to brucellosis.
Elchin Huseynov Mammad oglu
doaj   +3 more sources