Results 1 to 10 of about 154,628 (160)

Effects of Separate and Concomitant TLR-2 and TLR-4 Activation in Peripheral Blood Mononuclear Cells of Newborn and Adult Horses. [PDF]

open access: yesPLoS ONE, 2013
Deficient innate and adaptive immune responses cause newborn mammals to be more susceptible to bacterial infections than adult individuals. Toll-like receptors (TLRs) are known to play a pivotal role in bacterial recognition and subsequent immune ...
Johannes Cornelis Vendrig   +2 more
doaj   +17 more sources

Association of TLR-4 896A/G, TLR-4 1196C/T, and TLR-9 C/T polymorphism with schizophrenia in Indian Bengalee patient [PDF]

open access: yesIndian Journal of Psychiatry, 2022
Background: Chronic low-grade inflammation triggered by viral agents is a suggested etiological factor for schizophrenia. However, the underlying mechanism of inflammation and genetic predisposition to schizophrenia is poorly understood.
Jiwan Gurung   +3 more
doaj   +2 more sources

Randomized controlled trial of vitamin d supplementation on toll-like receptor-2 (tlr-2) and toll-like receptor-4 (tlr-4) in tuberculosis spondylitis patients [PDF]

open access: yesJournal of Orthopaedic Surgery and Research, 2023
Background Tuberculosis spondylitis accounts for approximately 50% of all cases of skeletal tuberculosis. Vitamin D plays a role in the immune system. Vitamin D helps in the activation of TLR-2 and TLR-4, which play a role in the process of tuberculosis ...
Jainal Arifin   +5 more
doaj   +2 more sources

Common variants in toll-like receptor family genes and risk of gastric cancer: a systematic review and meta-analysis

open access: yesFrontiers in Genetics, 2023
Background: An increasing number of studies have suggested the relationship between single-nucleotide polymorphisms (SNPs) in toll-like receptor (TLR) genes and gastric cancer (GC) susceptibility; however, the available evidence is contradictory.
Ayoub Al Othaim   +8 more
doaj   +1 more source

Influence of genetic variability in toll-like receptors (TLR 2, TLR 4, and TLR 9) on human immunodeficiency virus-1 disease progression

open access: yesInternational Journal of Mycobacteriology, 2023
Background: It has been demonstrated that toll-like receptors (TLR2), TLR4, and TLR9 which were initially known for recognizing bacterial products are involved in the detection of viral components.
Gaurav Kaushik, Richa Vashishtha
doaj   +1 more source

Acute Inflammation Is a Predisposing Factor for Weight Gain and Insulin Resistance

open access: yesPharmaceutics, 2022
In the course of infection and intense endotoxemia processes, induction of a catabolic state leading to weight loss is observed in mice and humans. However, the late effects of acute inflammation on energy homeostasis, regulation of body weight and ...
Edson Mendes de Oliveira   +8 more
doaj   +1 more source

Sophoricoside attenuates neuronal injury and altered cognitive function by regulating the LTR-4/NF-κB/PI3K signalling pathway in anaesthetic-exposed neonatal rats

open access: yesArchives of Medical Science, 2020
Introduction This study examined the protective effects of sophoricoside on neuronal injury and cognitive dysfunction in anaesthetic-exposed neonatal rats.
Lihua Yang, Yucan Xu, Wei Zhang
doaj   +1 more source

Assessment of the immunomodulatory properties of the probiotic strain Lactobacillus paracasei K5 in vitro and in vivo [PDF]

open access: yes, 2020
Lactobacillus paracasei K5 is a lactic acid bacteria (LAB) strain that has been isolated from dairy products. Previous studies have established its probiotic potential in a series of in vitro tests, including molecular characterization, safety profiling,
Alexopoulos, Athanasios   +9 more
core   +2 more sources

Aggregatibacter actinomycetemcomitans modulates toll-like receptors 2 and 4 in gingival epithelial cells in experimental periodontitis

open access: yesJournal of International Clinical Dental Research Organization, 2010
Background: Periodontitis is a common bacterial infection precipitated by exaggerated host responses to the oral microorganisms, As the first cells to encounter the oral pathogens the gingival epithelial cells (GEC) respond via toll-like receptors (TLR ...
Mythily Srinivasan   +2 more
doaj   +1 more source

Immunohistochemical Expression of TLR-4 in Temporomandibular Joint Dysfunction [PDF]

open access: yes, 2018
Objective Toll-like receptor 4 (TLR-4) is a transmembrane protein involved in the innate immune system and has been implicated in the pathogenesis of temporomandibular joint dysfunction (TMD).
Almeida, Luis Eduardo   +9 more
core   +2 more sources

Home - About - Disclaimer - Privacy