Results 11 to 20 of about 13,006,177 (289)

TLR-4 Signaling in Pericytes

, 2021
Introduction Pericytes are cells with intriguing properties that have only recently attracted the attention of numerous researchers. In the past years, their function was mainly associated with microvascular homeostasis, angiogenesis and maintenance ...
Elena Ranieri, Netti, Giuseppe Stefano, Ranieri, Elena, Castellano, Giuseppe, Stasi, Alessandra, Giuseppe Castellano, Giuseppe Stefano Netti, Loreto Gesualdo, Giovanni Stallone, Rossana Franzin, Franzin, Rossana, Gesualdo, Loreto, Alessandra Stasi, Stallone, Giovanni   +13 more
core   +3 more sources

Expression of TLR-4 and -2 in peripheral mononuclear cells in renal transplant patients with TLR-4 gene polymorphism

International Immunopharmacology, 2010
Introduction: TLR-4 has also been identified as a receptor for endogenous alarmins, which are increased post transplantation. TLR-4 has also been associated with a polymorphism that could impact graft outcome. Objective: To assess the expression of TLR-4
Milena Karina Colló Brunialti, Alvaro Pacheco-Silva, Salomao, Reinaldo [UNIFESP], Nogueira, Eliana [UNIFESP], CENEDEZE, Marcos A., Kikumi S. Ozaki, Saraiva Camara, Niels Olsen, Eliana Nogueira, MARQUES, Georgia D. M., BRUNIALTI, Milena Karina Collo, NOGUEIRA, Eliana, Marcos A. Cenedeze, Niels Olsen Saraiva Câmara, Reinaldo Salomao, Collo Brunialti, Milena Karina [UNIFESP], OZAKI, Kikumi S., PACHECO-SILVA, Alvaro, CAMARA, Niels Olsen Saraiva, Geórgia D.M. Marques, SALOMAO, Reinaldo   +19 more
core   +4 more sources

TLR-2 Arg753Gln, TLR-4 Asp299Gly, and TLR-4 Thr399Ile polymorphisms in Henoch Schonlein purpura with and without renal involvement

Rheumatology International, 2010
Infections may trigger or aggravate glomerulonephritidis and renal vasculitis like Henoch Schonlein purpura (HSP). HSP is seen more frequently in patients with familial Mediterranean fever in which TLR-2 Arg753Gln polymorphism frequency is increased ...
CİNGÖZ, SULTAN, Demir, Belde Kasap, SOYLU, ALPER, Sakizli, Meral, Turkmen, Mehmet, KAVUKÇU, SALİH, KIZILDAĞ, SEFA   +6 more
core   +4 more sources

The role of TLR-4 in chemoresistance of cancer. [PDF]

Discov Oncol
Abstract Chemotherapy, which aims to eradicate tumor cells and enhance patient survival, is a prevalent approach for tumor treatment. Nevertheless, recurrence and drug resistance resulting from consecutive chemotherapy regimens have emerged as significant factors contributing to the high fatality rates among cancer patients.
Li Y, Tang T, Sun Y, Chen G, Yuan X, Cai.   +5 more
europepmc   +4 more sources

Subcellular organelle lipidomics in TLR-4-activated macrophages [PDF]

Journal of Lipid Research, 2010
Lipids orchestrate biological processes by acting remotely as signaling molecules or locally as membrane components that modulate protein function. Detailed insight into lipid function requires knowledge of the subcellular localization of individual lipids.
Alexander Y, Andreyev, Eoin, Fahy, Ziqiang, Guan, Samuel, Kelly, Xiang, Li, Jeffrey G, McDonald, Stephen, Milne, David, Myers, Hyejung, Park, Andrea, Ryan, Bonne M, Thompson, Elaine, Wang, Yihua, Zhao, H Alex, Brown, Alfred H, Merrill, Christian R H, Raetz, David W, Russell, Shankar, Subramaniam, Edward A, Dennis   +18 more
openaire   +2 more sources

Hyperresponsiveness of Corticoid-Resistant Th17/Tc-17 Cells to TLR-2 and TLR-4 Ligands is a Feature of Multiple Sclerosis Patients at Higher Risk of Therapy Failure. [PDF]

J Inflamm Res
Joana Hygino,1,* Marisa C Sales,2,* Priscila M Sacramento,1 Taissa M Kasahara,3 Júlio César Costa da Silva,3 Rafaela Bilhão,3 Regis M Andrade,4 Cláudia Cristina Ferreira Vasconcelos,1 Cleonice AM Bento1,3– 5 1Post-Graduate Program in Neurology ...
Hygino J, Sales MC, Sacramento PM, Kasahara TM, da Silva JCC, Bilhão R, Andrade RM, Vasconcelos CCF, Bento CAM.   +8 more
europepmc   +2 more sources

A study of the modulation of Toll-like receptor signalling in macrophages by Annexin-1 [PDF]

, 2011
PhDAnnexin-A1 (AnxA1) is an endogenous anti-inflammatory protein that has been shown to exert a protective role against the lethal effects induced by the Toll-like receptor (TLR) 4 agonist lipopolysaccharide (LPS).
Polycarpou, Anastasia
core   +4 more sources

TLR-4 and VEGF Polymorphisms in Chronic Periaortitis

PLoS ONE, 2013
Chronic periaortitis (CP) is a rare disease that is characterised by fibro-inflammatory tissue surrounding the abdominal aorta and has both non-aneurysmal (idiopathic retroperitoneal fibrosis [IRF]) and aneurysmal forms (inflammatory abdominal aortic aneurysm [IAAA]).
Cordula M. Stover, Fabiola Atzeni, Luigi Boiardi, VAGLIO, Augusto, Davide Nicoli, Enrico Farnetti, Alessandra Palmisano, Nicolò Pipitone, Davide Martorana, Gabriella Moroni, Selena Longhi, Francesco Bonatti, BUZIO, Carlo, Carlo Salvarani   +13 more
openaire   +6 more sources

Effects of empagliflozin on a model of chronic depression and brain Toll-like receptors gene expression in male rats

Medical Journal of Babylon, 2023
Background: Empagliflozin is an antidiabetic medication having anti-inflammatory and antioxidant properties. Objectives: To develop a chronic unpredictable stress (CUS) model in male rats, evaluate empagliflozin’s antidepressant effects, and describe the
Hatem Kareem Mijwel, Salman M Salman, Alaa H Al-Charrakh   +2 more
doaj   +1 more source

Vernal keratoconjunctivitis activity induces decrease of ocular surface CD14, TLR-4 and TLR-9 expression

, 2022
Purpose: CD14 is involved in the modulation of immune reaction via toll-like receptors (TLR) and may influence the development of allergic diseases. The role of CD14 in vernal keratoconjunctivitis (VKC) has not yet been investigated.
Nebbioso, Marcella, Lambiase, Alessandro, Bruscolini, Alice, Sacchetti, Marta, Segatto, Marco, Abicca, Irene, Zicari, Anna Maria   +6 more
core   +1 more source