Results 11 to 20 of about 136,864 (160)
The role of TLR-4 in chemoresistance of cancer. [PDF]
Discov OncolAbstract Chemotherapy, which aims to eradicate tumor cells and enhance patient survival, is a prevalent approach for tumor treatment. Nevertheless, recurrence and drug resistance resulting from consecutive chemotherapy regimens have emerged as significant factors contributing to the high fatality rates among cancer patients.
Li Y +5 more
europepmc +4 more sources
Subcellular organelle lipidomics in TLR-4-activated macrophages [PDF]
Journal of Lipid Research, 2010 Lipids orchestrate biological processes by acting remotely as signaling molecules or locally as membrane components that modulate protein function. Detailed insight into lipid function requires knowledge of the subcellular localization of individual lipids.
Alexander Y, Andreyev +18 more
openaire +2 more sources
TLR-4 and VEGF Polymorphisms in Chronic Periaortitis
PLoS ONE, 2013 Chronic periaortitis (CP) is a rare disease that is characterised by fibro-inflammatory tissue surrounding the abdominal aorta and has both non-aneurysmal (idiopathic retroperitoneal fibrosis [IRF]) and aneurysmal forms (inflammatory abdominal aortic aneurysm [IAAA]).
Cordula M. Stover +13 more
openaire +6 more sources
TLR-4 Regulates CD8+ T Cell Trapping in the Liver [PDF]
The Journal of Immunology, 2005 Abstract Mammalian TLRs are understood primarily as an activating system for innate and adaptive immunity, but have also been implicated in sensing cellular damage and in promoting intestinal integrity. In this study we show that TLR-4 also controls the in vivo distribution of activated CD8+ T cells.
Beena, John, Ian Nicholas, Crispe
openaire +2 more sources
Zaporožskij Medicinskij Žurnal, 2018 The aim of the research is to establish an association between Arg753Gln polymorphism of TLR-2 gene, Leu412Phe of TLR-3 gene, Asp299Gly of TLR-4 gene and susceptibility to inflammatory diseases of the upper and lower respiratory tract and the complicated
N. O. Pryimenko +4 more
doaj +1 more source
Medical Journal of Babylon, 2023 Background: Empagliflozin is an antidiabetic medication having anti-inflammatory and antioxidant properties. Objectives: To develop a chronic unpredictable stress (CUS) model in male rats, evaluate empagliflozin’s antidepressant effects, and describe the
Hatem Kareem Mijwel +2 more
doaj +1 more source
International Immunopharmacology, 2010 TLR-4 has also been identified as a receptor for endogenous alarmins, which are increased post transplantation. TLR-4 has also been associated with a polymorphism that could impact graft outcome.To assess the expression of TLR-4 in kidney transplant patients carrying or not a polymorphism.TLR-4 polymorphism (A299G/T399I) was studied in 200 renal ...
Nogueira, Eliana UNIFESP +7 more
openaire +3 more sources
Italian Journal of Animal Science, 2022 The goal of this study was to look into the effect of two probiotics as feed additives: Biosol (lipotropic factor containing probiotics) and/or Zemos, and to determine the best regimen for using both probiotics to improve growth performance, carcass ...
Nessma Hassan +4 more
doaj +1 more source
The Distinctive Activation of Toll-Like Receptor 4 in Human Samples with Sepsis
Cells, 2022 Clinical success of Toll-Like receptor-4 (TLR-4) antagonists in sepsis therapy has thus far been lacking. As inhibition of a receptor can only be useful if the receptor is active, stratification of patients with active TLR-4 would be desirable.
Patrick Thon +16 more
doaj +1 more source
Immunohistochemical expression of TLR-4 in temporomandibular joint dysfunction
CRANIO®, 2018 Objective Toll-like receptor 4 (TLR-4) is a transmembrane protein involved in the innate immune system and has been implicated in the pathogenesis of temporomandibular joint dysfunction (TMD). The purpose of this study was to histologically examine the level of expression of TLR-4 relative to severity of TMD.
Luis Eduardo Almeida +9 more
openaire +3 more sources