Results 11 to 20 of about 136,665 (214)

Single nucleotide polymorphisms of TLR-2, TLR-3, TLR-4 and susceptibility to inflammatory diseases of the respiratory tract

Zaporožskij Medicinskij Žurnal, 2018
The aim of the research is to establish an association between Arg753Gln polymorphism of TLR-2 gene, Leu412Phe of TLR-3 gene, Asp299Gly of TLR-4 gene and susceptibility to inflammatory diseases of the upper and lower respiratory tract and the complicated
N. O. Pryimenko, T. M. Kotelevska, H. M. Dubynska, I. P. Kaidashev, K. V. Pikul   +4 more
doaj   +1 more source

Effects of empagliflozin on a model of chronic depression and brain Toll-like receptors gene expression in male rats

Medical Journal of Babylon, 2023
Background: Empagliflozin is an antidiabetic medication having anti-inflammatory and antioxidant properties. Objectives: To develop a chronic unpredictable stress (CUS) model in male rats, evaluate empagliflozin’s antidepressant effects, and describe the
Hatem Kareem Mijwel, Salman M Salman, Alaa H Al-Charrakh   +2 more
doaj   +1 more source

Effects of probiotic feed additives (biosol and Zemos) on growth and related genes in broiler chickens

Italian Journal of Animal Science, 2022
The goal of this study was to look into the effect of two probiotics as feed additives: Biosol (lipotropic factor containing probiotics) and/or Zemos, and to determine the best regimen for using both probiotics to improve growth performance, carcass ...
Nessma Hassan, Ismail Mostafa, Mohamed A. Elhady, Marwa A. Ibrahim, Hassan Amer   +4 more
doaj   +1 more source

The Distinctive Activation of Toll-Like Receptor 4 in Human Samples with Sepsis

Cells, 2022
Clinical success of Toll-Like receptor-4 (TLR-4) antagonists in sepsis therapy has thus far been lacking. As inhibition of a receptor can only be useful if the receptor is active, stratification of patients with active TLR-4 would be desirable.
Patrick Thon, Katharina Rump, Annika Knorr, Birte Dyck, Dominik Ziehe, Matthias Unterberg, Hartmuth Nowak, Lars Bergmann, Alexander Wolf, Maha Bazzi, Jennifer Orlowski, Marcus Peters, Alexander Zarbock, Thorsten Brenner, Michael Adamzik, Tim Rahmel, Björn Koos   +16 more
doaj   +1 more source

Evaluation of Toll-Like receptor 2 and 4 RNA expression and the cytokine profile in postmenopausal women with metabolic syndrome. [PDF]

PLoS ONE, 2014
OBJECTIVE: To evaluate the gene expression of Toll-Like (TLR-2 and TLR-4) receptors and cytokine profile in postmenopausal women with or without metabolic syndrome (MetS).
Claudio Lera Orsatti, Eliana Aguiar Petri Nahas, Jorge Nahas-Neto, Fabio Lera Orsatti, Vanessa Innocenti Giorgi, Steven S Witkin   +5 more
doaj   +1 more source

Role of toll-like receptor 4 in eliciting adaptive immune responses against recombinant BCG expressing the C-terminus of merozoite surface protein-1 of Plasmodium falciparum

Asian Pacific Journal of Tropical Biomedicine, 2019
Objective: To determine the role of toll-like receptor 4 (TLR-4) in eliciting cellular and humoral immune responses against recombinant Mycobacterium bovis bacille Calmette-Guérin (rBCG) expressing the C-terminus of merozoite surface protein-1 of ...
Muhammad A Abbas, Rapeah Suppian
doaj   +1 more source

Patterns of milk productivity associated with biochemical parameters and expressions of the HSPs and Toll Like genes in dairy buffaloes

Medicina Veterinária
The aim of this study was to verify milk productivity associated with biochemical parameters and expression of stress marker genes (HSP70, HSP90?, HSP90?) and immunity (TLR-2 and TLR-4) in dairy buffaloes.
Henrique Low Nogueira, Elem Cristina Macedo Barra de Sousa, Cintia Luana Pinheiro Santos, Ednaldo Silva Filho, Priscila Di Paula Bessa Santana   +4 more
doaj   +5 more sources

Effects of lime (Citrus aurantifolia) peel to the expression of mRNA toll-like receptors 4 in balb/c mice-infected Salmonella typhi

Journal of Advanced Pharmaceutical Technology & Research, 2020
Lime peel contains metabolic compounds that have lethal effects of bacterial cells, but its effect as an antibacterial modulate innate immunity pathways, especially toll-like receptor 4 (TLR-4) signaling pathway, is unclear.
Vivien Novarina Kasim, Mochammad Hatta, Rosdiana Natzir, Veni Hadju, Ami Febriza, Hasta Handayani Idrus   +5 more
doaj   +1 more source

Benificial effect of stachydrine on the traumatic brain injury induced neurodegeneration by attenuating the expressions of Akt/mTOR/PI3K and TLR4/NFκ-B pathway

Translational Neuroscience, 2018
Present investigation aims to explore the protective effect of stachydrine against traumatic brain injury (TBI) and also investigate the molecular mechanism of its action. TBI was induced by the fall a hammer (450 g) from the height of 1.5 m.
Yu Nianzu, Hu Si, Hao Zheng
doaj   +1 more source

Effects of Separate and Concomitant TLR-2 and TLR-4 Activation in Peripheral Blood Mononuclear Cells of Newborn and Adult Horses. [PDF]

PLoS ONE, 2013
Deficient innate and adaptive immune responses cause newborn mammals to be more susceptible to bacterial infections than adult individuals. Toll-like receptors (TLRs) are known to play a pivotal role in bacterial recognition and subsequent immune ...
Johannes Cornelis Vendrig, Luc Edgar Coffeng, Johanna Fink-Gremmels   +2 more
doaj   +1 more source