Results 31 to 40 of about 154,777 (303)

Interleukin-12 p40 secretion by cutaneous CD11c(+) and F4/80(+) cells is a major feature of the innate immune response in mice that develop Th1-mediated protective immunity to Schistosoma mansoni [PDF]

, 2003
Radiation-attenuated (RA) schistosome larvae are potent stimulators of innate immune responses at the skin site of exposure (pinna) that are likely to be important factors in the development of Th1-mediated protective immunity.
Anderson, S, Hogg, K G, Kumkate, S, Mountford, A P   +3 more
core   +2 more sources

Patterns of milk productivity associated with biochemical parameters and expressions of the HSPs and Toll Like genes in dairy buffaloes

Medicina Veterinária
The aim of this study was to verify milk productivity associated with biochemical parameters and expression of stress marker genes (HSP70, HSP90?, HSP90?) and immunity (TLR-2 and TLR-4) in dairy buffaloes.
Henrique Low Nogueira, Elem Cristina Macedo Barra de Sousa, Cintia Luana Pinheiro Santos, Ednaldo Silva Filho, Priscila Di Paula Bessa Santana   +4 more
doaj   +5 more sources

Role of toll-like receptor 4 in eliciting adaptive immune responses against recombinant BCG expressing the C-terminus of merozoite surface protein-1 of Plasmodium falciparum

Asian Pacific Journal of Tropical Biomedicine, 2019
Objective: To determine the role of toll-like receptor 4 (TLR-4) in eliciting cellular and humoral immune responses against recombinant Mycobacterium bovis bacille Calmette-Guérin (rBCG) expressing the C-terminus of merozoite surface protein-1 of ...
Muhammad A Abbas, Rapeah Suppian
doaj   +1 more source

Prothymosin a and a prothymosin α-derived peptide enhance TH1-type immune responses against defined HER-2/neu epitopes [PDF]

, 2013
Background: Active cancer immunotherapies are beginning to yield clinical benefit, especially those using peptide-pulsed dendritic cells (DCs). Different adjuvants, including Toll-like receptor (TLR) agonists, commonly co-administered to cancer patients ...
Derhovanessian, Evelyna, Ioannou, Kyriaki, Kalbacher, Hubert, Pawelec, Graham, Samara, Pinelopi, Trougakos, Ioannis P., Tsakiri, Eleni, Tsitsilonis, Ourania E., Voelter, Wolfgang   +8 more
core   +1 more source

Effects of lime (Citrus aurantifolia) peel to the expression of mRNA toll-like receptors 4 in balb/c mice-infected Salmonella typhi

Journal of Advanced Pharmaceutical Technology & Research, 2020
Lime peel contains metabolic compounds that have lethal effects of bacterial cells, but its effect as an antibacterial modulate innate immunity pathways, especially toll-like receptor 4 (TLR-4) signaling pathway, is unclear.
Vivien Novarina Kasim, Mochammad Hatta, Rosdiana Natzir, Veni Hadju, Ami Febriza, Hasta Handayani Idrus   +5 more
doaj   +1 more source

HMGB1-Induced Cross Talk between PTEN and miRs 221/222 in Thyroid Cancer [PDF]

, 2015
High mobility group box 1 (HMGB1) is an ubiquitous protein that plays different roles in the nucleus, cytoplasm and extra-cellular space. It is an important DAMP molecule that allows communication between damaged or tumor cells and the immune system ...
ANTONACI, Alfredo, FAGGIONI, Alberto, Fico, F., MARDENTE, Stefania, MARI, EMANUELA, MASSIMI, ISABELLA, PULCINELLI, FABIO MARIA, ZICARI, Alessandra   +7 more
core   +4 more sources

Toll-like receptor-4 signaling pathway in aorta aging and diseases: "its double nature" [PDF]

, 2017
Recent advances in the field of innate immunity have revealed a complex role of innate immune signaling pathways in both tissue homeostasis and disease.
Balistreri, C., Lio, D., Madonna, R., Ruvolo, G.   +3 more
core   +1 more source

TLR-4/Wnt modulation as new therapeutic strategy in the treatment of glioblastomas [PDF]

Oncotarget, 2018
Glioblastomas are highly aggressive brain tumors. Various pathways are involved in gliomagenesis, among which the Wingless (Wnt) signaling. Dickkopf protein-related protein 3 (Dkk-3) interacts with proteins of Wnt pathwayas inhibitor. The Wnt signaling contributes to activity of the claudins, that are critical components of tight junctions, whose ...
Casili, Giovanna, Caffo, Maria, Campolo, Michela, Barresi, Valeria, Caruso, Gerardo, Cardali, Salvatore M, Lanza, Marika, Mallamace, Raffaella, Filippone, Alessia, Conti, Alfredo, Germanò, Antonino, Cuzzocrea, Salvatore, Esposito, Emanuela   +12 more
openaire   +4 more sources

Benificial effect of stachydrine on the traumatic brain injury induced neurodegeneration by attenuating the expressions of Akt/mTOR/PI3K and TLR4/NFκ-B pathway

Translational Neuroscience, 2018
Present investigation aims to explore the protective effect of stachydrine against traumatic brain injury (TBI) and also investigate the molecular mechanism of its action. TBI was induced by the fall a hammer (450 g) from the height of 1.5 m.
Yu Nianzu, Hu Si, Hao Zheng
doaj   +1 more source

Toll-like Receptors 2 and 4 and Their Mutations in Patients with Otitis Media and Middle Ear Effusion [PDF]

Clinical and Experimental Otorhinolaryngology, 2008
ObjectivesToll-like receptors (TLRs) detect microbial infections and they can directly induce innate host defense responses. TLR 2 has been shown to be primarily involved in the recognition of peptidoglycans and lipoteichoic acid of gram positive ...
Young Chan Lee, Chul Kim, Ju Sup Shim, Jae Yong Byun, Mun Suh Park, Chang Il Cha, Young Il Kim, Jin Woo Lee, Seung Geun Yeo   +8 more
doaj   +1 more source