Results 31 to 40 of about 136,864 (160)
Effects of Toll-Like Receptors 3 and 4 in the Osteogenesis of Stem Cells
Stem Cells International, 2014 Objective. To investigate the effects of Toll-like receptors in stem cell osteogenesis. Methods. Bone marrow mesenchymal stem cells (BMSCs) were divided into the blank group, the TLR-3 activated group, and the TLR-4 activated group.
Chen Qi, Xu Xiaofeng, Wang Xiaoguang
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TLR-4/Wnt modulation as new therapeutic strategy in the treatment of glioblastomas [PDF]
Oncotarget, 2018 Glioblastomas are highly aggressive brain tumors. Various pathways are involved in gliomagenesis, among which the Wingless (Wnt) signaling. Dickkopf protein-related protein 3 (Dkk-3) interacts with proteins of Wnt pathwayas inhibitor. The Wnt signaling contributes to activity of the claudins, that are critical components of tight junctions, whose ...
Casili, Giovanna +12 more
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Expression of Toll-like receptors 2 and 4 in gingivitis and chronic periodontitis.
Indian Journal of Dental Research, 2006 Periodontal disease is the major cause of adult tooth loss and is commonly characterized by a chronic inflammation caused by infection by oral bacteria.
Sarah S +3 more
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Evaluation of the constitutive expression levels of ch-TLR 3, ch-TLR 4, ch-TLR 15 and ch-TLR 21 genes in the Peripheral Blood Mononuclear Cells of native Indian poultry breeds, Aseel and Kadaknath [PDF]
Veterinary World, 2013 Aim: To assess the basal constitutive expression levels of ch-TLR3, ch-TLR 4, ch-TLR 15 and ch-TLR 21 in the peripheral blood mononuclear cells (PBMCs) in Aseel and Kadaknath chicks (Indian native poultry breeds) and to evaluate the differences in their ...
H. C. Chauhan +7 more
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Medical Journal of BabylonBackground: Multiple sclerosis (MS) is a chronic autoimmune, inflammatory neurological disease affecting the central nervous system (CNS). MS damages the myelinated axons; in the CNS; partially damaging the myelin sheath and axons.
Abrar J. Hassan, Rana Saady Aboud
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Synthetic Toll like receptor-4 (TLR-4) agonist peptides as a novel class of adjuvants. [PDF]
PLoS ONE, 2012 Adjuvants serve as catalysts of the innate immune response by initiating a localized site of inflammation that is mitigated by the interactions between antigens and toll like receptor (TLR) proteins.
Arulkumaran Shanmugam +5 more
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Drug Design, Development and Therapy, 2022 Shaymaa Ramzy Senousy,1 Al-Shaimaa F Ahmed,1 Dalia A Abdelhafeez,2 Mohamed Montaser A Khalifa,1 Mohammed AS Abourehab,3 Mahmoud El-Daly1 1Department of Pharmacology and Toxicology, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt; 2Department ...
Senousy SR +5 more
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Veterinary Research, 2023 Previous studies showed that Trichinella spiralis galectin (Tsgal) facilitates larval invasion of intestinal epithelium cells (IECs). However, IEC proteins binding with Tsgal were not identified, and the mechanism by which Tsgal promotes larval invasion ...
Kai Ning Ma +9 more
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Specificity of eicosanoid production depends on the TLR-4-stimulated macrophage phenotype [PDF]
Journal of Leukocyte Biology, 2011 ABSTRACTEicosanoid metabolism differs in profile and quantity between macrophages of different tissue origin and method of elicitation, as well as between primary and immortalized macrophages after activation with inflammatory stimuli. Using a lipidomic approach, we comprehensively analyzed the eicosanoids made by murine RPMs, TGEMs, BMDM, and the ...
Norris, Paul C +4 more
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Role of toll-like receptor 4 in colorectal carcinogenesis: a meta-analysis.
PLoS ONE, 2014 ObjectiveThis meta-analysis was performed to evaluate the role of toll-like receptor 4 (TLR-4) in colorectal carcinogenesis.MethodsThe PubMed, CISCOM, CINAHL, Web of Science, Google Scholar, EBSCO, Cochrane Library, and CBM databases were searched from ...
Xiao-Xia Li +8 more
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