Results 51 to 60 of about 13,006,177 (289)

Expression of Toll-like receptors 2 and 4 in gingivitis and chronic periodontitis.

Indian Journal of Dental Research, 2006
Periodontal disease is the major cause of adult tooth loss and is commonly characterized by a chronic inflammation caused by infection by oral bacteria.
Sarah S, Tamilselvan S, Kamatchiammal S, Suresh R   +3 more
doaj  

Immunological and Molecular Detection of Helicobacter pylori in Patients Clinically Diagnosed with Multiple Sclerosis

Medical Journal of Babylon
Background: Multiple sclerosis (MS) is a chronic autoimmune, inflammatory neurological disease affecting the central nervous system (CNS). MS damages the myelinated axons; in the CNS; partially damaging the myelin sheath and axons.
Abrar J. Hassan, Rana Saady Aboud
doaj   +1 more source

Evaluation of the constitutive expression levels of ch-TLR 3, ch-TLR 4, ch-TLR 15 and ch-TLR 21 genes in the Peripheral Blood Mononuclear Cells of native Indian poultry breeds, Aseel and Kadaknath [PDF]

Veterinary World, 2013
Aim: To assess the basal constitutive expression levels of ch-TLR3, ch-TLR 4, ch-TLR 15 and ch-TLR 21 in the peripheral blood mononuclear cells (PBMCs) in Aseel and Kadaknath chicks (Indian native poultry breeds) and to evaluate the differences in their ...
H. C. Chauhan, B. S. Chandel, N. M. Shah, Abidali Dadawala, Pankaj Kumar, Hemen Das, Meeta V. Patel, H. N. Kher   +7 more
doaj   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Alpha-Chymotrypsin Protects Against Acute Lung, Kidney, and Liver Injuries and Increases Survival in CLP-Induced Sepsis in Rats Through Inhibition of TLR4/NF-κB Pathway

Drug Design, Development and Therapy, 2022
Shaymaa Ramzy Senousy,1 Al-Shaimaa F Ahmed,1 Dalia A Abdelhafeez,2 Mohamed Montaser A Khalifa,1 Mohammed AS Abourehab,3 Mahmoud El-Daly1 1Department of Pharmacology and Toxicology, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt; 2Department ...
Senousy SR, Ahmed ASF, Abdelhafeez DA, Khalifa MMA, Abourehab MAS, El-Daly M   +5 more
doaj  

Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light

Advanced Science, EarlyView.
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley   +1 more source

The role of TLR-2, TLR-3, TLR-4 genes polymorphism in case of grippe

, 2014
В данной статье изучены распространенность и прогностическое значение полиморфизма Arg753Gln гена TLR-2, Leu412Phe TLR-3, Asp299Gly TLR-4 при гриппе.
Кайдашев, Игорь Петрович, Чуб, Костянтин Федорович, Dubynska, G., Похилько, Валерий Иванович, Прийменко, Наталія Олегівна, Дубинська, Галина Михайлівна, Pryimenko, N. O., Chub, K. F., Чуб, Константин Федорович, Kaidashev, I., Pokhylko, V. I., Прийменко, Наталья Олеговна, Кайдашев, Ігор Петрович, Дубинская, Галина Михайловна, Похилько, Валерій Іванович   +14 more
core   +1 more source

Novel mutations in the toll like receptor genes cause hyporesponsiveness to Mycobacterium avium subsp. paratuberculosis infection [PDF]

, 2008
Toll like receptors play a central role in the recognition of pathogen associated molecular patterns (PAMPs). Mutations in TLR1, TLR2 and TLR4 genes may change the PAMP reorganization ability which causes altered responsiveness to the bacterial pathogens.
Rostislav Skrabana, Michal Novak, Mangesh Bhide, Ivan Mikula Jr., Rastislav Mucha, Lucia Kisova, Ivan Mikula Sr.   +6 more
core  

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Postischemic vascular permeability requires both TLR-2 and TLR-4, but only TLR-2 mediates the transendothelial migration of leukocytes.

, 2009
Ischemia-reperfusion (I/R) activates innate immunity involving Toll-like receptor (TLR) 2 and TLR-4 signaling. Leukocyte migration and vascular permeability contribute to postischemic tissue damage.
Khandoga, AG;Khandoga, A;Anders, HJ;Krombach, F
core   +1 more source