Results 61 to 70 of about 13,006,177 (289)
Expression of TLR-4 in epithelial serous ovarian cancer
Korean Journal of Gynecologic Oncology, 2007 Objective : This study was to determine the expression of Toll-like receptor 4 (TLR-4) in ovarian serous adenocarcinoma tissues. Methods : TLR-4 expression was evaluated at the RNA level by real-time quantitative RT-PCR, in 24 fresh frozen ovarian serous adenocarcinoma tissues and 9 normal ovarian tissues.
Chel Hun Choi +7 more
openaire +1 more source
Advanced Science, EarlyView.Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha +4 more
wiley +1 more source
Role of toll-like receptor 4 in colorectal carcinogenesis: a meta-analysis.
PLoS ONE, 2014 ObjectiveThis meta-analysis was performed to evaluate the role of toll-like receptor 4 (TLR-4) in colorectal carcinogenesis.MethodsThe PubMed, CISCOM, CINAHL, Web of Science, Google Scholar, EBSCO, Cochrane Library, and CBM databases were searched from ...
Xiao-Xia Li +8 more
doaj +1 more source
Frontiers in Immunology, 2020 Chromoblastomycosis is a chronic and progressive subcutaneous mycosis caused mainly by the fungus Fonsecaea pedrosoi. The infection is characterized by erythematous papules and histological sections demonstrating an external layer of fibrous tissue and ...
Leandro Carvalho Dantas Breda +11 more
doaj +1 more source
Synthetic Toll like receptor-4 (TLR-4) agonist peptides as a novel class of adjuvants. [PDF]
PLoS ONE, 2012 Adjuvants serve as catalysts of the innate immune response by initiating a localized site of inflammation that is mitigated by the interactions between antigens and toll like receptor (TLR) proteins.
Arulkumaran Shanmugam +5 more
doaj +1 more source
Advanced Science, EarlyView.Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song +5 more
wiley +1 more source
Veterinary Research, 2023 Previous studies showed that Trichinella spiralis galectin (Tsgal) facilitates larval invasion of intestinal epithelium cells (IECs). However, IEC proteins binding with Tsgal were not identified, and the mechanism by which Tsgal promotes larval invasion ...
Kai Ning Ma +9 more
doaj +1 more source
Aggregation Behavior of an Ultra-Pure Lipopolysaccharide that Stimulates TLR-4 Receptors [PDF]
Biophysical Journal, 2008 The innate immune systems of humans and other animals are activated by lipopolysaccharides (LPS), which are glucosamine-based phospholipids that form the outer leaflet of the outer membranes of Gram-negative bacteria. Activation involves interactions of LPS with the innate immunity-receptor comprised of toll-like receptor 4 in complex with so-called MD-
Sasaki, Hirotaka, White, Stephen H
openaire +3 more sources
Advanced Science, EarlyView.The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt +16 more
wiley +1 more source
Down‐regulation of TLR‐4 in Hypoxic Myoblast Cells
The FASEB Journal, 2013 Intrauterine hypoxia is a common complication of human pregnancy. Intima hyperplasia and increased expression of inflammatory markers in aortae of chronically hypoxic fetuses were demonstrated previously. Objective To determine the ...
Jennifer Anne Thompson, R. Clinton Webb
openaire +1 more source