Results 61 to 70 of about 154,777 (303)

Expression of Toll-like receptors 2 and 4 in gingivitis and chronic periodontitis.

Indian Journal of Dental Research, 2006
Periodontal disease is the major cause of adult tooth loss and is commonly characterized by a chronic inflammation caused by infection by oral bacteria.
Sarah S, Tamilselvan S, Kamatchiammal S, Suresh R   +3 more
doaj  

Evaluation of the constitutive expression levels of ch-TLR 3, ch-TLR 4, ch-TLR 15 and ch-TLR 21 genes in the Peripheral Blood Mononuclear Cells of native Indian poultry breeds, Aseel and Kadaknath [PDF]

Veterinary World, 2013
Aim: To assess the basal constitutive expression levels of ch-TLR3, ch-TLR 4, ch-TLR 15 and ch-TLR 21 in the peripheral blood mononuclear cells (PBMCs) in Aseel and Kadaknath chicks (Indian native poultry breeds) and to evaluate the differences in their ...
H. C. Chauhan, B. S. Chandel, N. M. Shah, Abidali Dadawala, Pankaj Kumar, Hemen Das, Meeta V. Patel, H. N. Kher   +7 more
doaj   +1 more source

Nucleosomes and neutrophil extracellular traps in septic and burn patients [PDF]

, 2017
NETosis is a host defense mechanism associated with inflammation and tissue damage. Experimental models show that platelets and von Willebrand factor (VWF) are key elements for intravascular NETosis. We determined NETosis in septic and burn patients at 1
Carestia, Agostina, D'Atri, Lina Paola, Fandiño, María Eugenia, Fondevila, Carlos, Guzman, María Alejandra, Kaufman, Tomás, Magosevich, Débora, Moreno, María Carolina, Schattner, Mirta Ana   +8 more
core   +1 more source

Matrix Viscoelasticity Regulates Dendritic Cell Migration and Immune Priming

Advanced Materials, EarlyView.
Matrix viscoelasticity is a key mechanical feature of the tumor microenvironment but remains poorly understood in immune regulation. Here, we develop a tunable collagen platform to decouple viscoelasticity from stiffness and show that slow‐relaxing matrices constrain dendritic cell migration by limiting actomyosin‐driven matrix remodeling, thereby ...
Wei‐Hung Jung, Emie Humann, Joshua M. Price, Yoav Binenbaum, Azra Haseki, Sanjana Iyer, David J. Mooney   +6 more
wiley   +1 more source

Synthetic Toll like receptor-4 (TLR-4) agonist peptides as a novel class of adjuvants. [PDF]

PLoS ONE, 2012
Adjuvants serve as catalysts of the innate immune response by initiating a localized site of inflammation that is mitigated by the interactions between antigens and toll like receptor (TLR) proteins.
Arulkumaran Shanmugam, Shilpi Rajoria, Andrea L George, Abraham Mittelman, Robert Suriano, Raj K Tiwari   +5 more
doaj   +1 more source

Lipopolysaccharide and toll-like receptor 4 in dogs with congenital portosystemic shunts [PDF]

, 2015
Surgical attenuation of a congenital portosystemic shunt (CPSS) results in increased portal vein perfusion, liver growth and clinical improvement. Portal lipopolysaccharide (LPS) is implicated in liver regeneration via toll-like receptor (TLR) 4 mediated
House, A K, Lipscomb, V J, Smith, K C, Tivers, M S, Wheeler-Jones, C P D   +4 more
core   +4 more sources

Sea Urchin‐Inspired Immuno‐Instructive Ionic Flow Drives MSCs‐Macrophage Communication to Promote Bone Regeneration

Advanced Materials, EarlyView.
ABSTRACT Bone tissue regeneration is a complex physiological process dependent on the spatiotemporal coordination of immune cells and stem cells. Conventional research primarily elucidates the mechanism through which materials facilitate bone formation by initially modulating macrophages and subsequently encouraging the osteogenic differentiation of ...
Yang Lu, Kun Su, Daqian Liu, Chunyu Liu, Muyan Qin, Shuaijie Li, Pengfei Tian, Yansong Wang, Yingbo Wang, Lei Chu, Xu Cui, Haobo Pan   +11 more
wiley   +1 more source

Immunological and Molecular Detection of Helicobacter pylori in Patients Clinically Diagnosed with Multiple Sclerosis

Medical Journal of Babylon
Background: Multiple sclerosis (MS) is a chronic autoimmune, inflammatory neurological disease affecting the central nervous system (CNS). MS damages the myelinated axons; in the CNS; partially damaging the myelin sheath and axons.
Abrar J. Hassan, Rana Saady Aboud
doaj   +1 more source

Alpha-Chymotrypsin Protects Against Acute Lung, Kidney, and Liver Injuries and Increases Survival in CLP-Induced Sepsis in Rats Through Inhibition of TLR4/NF-κB Pathway

Drug Design, Development and Therapy, 2022
Shaymaa Ramzy Senousy,1 Al-Shaimaa F Ahmed,1 Dalia A Abdelhafeez,2 Mohamed Montaser A Khalifa,1 Mohammed AS Abourehab,3 Mahmoud El-Daly1 1Department of Pharmacology and Toxicology, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt; 2Department ...
Senousy SR, Ahmed ASF, Abdelhafeez DA, Khalifa MMA, Abourehab MAS, El-Daly M   +5 more
doaj  

Trichinella spiralis galectin binding to toll-like receptor 4 induces intestinal inflammation and mediates larval invasion of gut mucosa

Veterinary Research, 2023
Previous studies showed that Trichinella spiralis galectin (Tsgal) facilitates larval invasion of intestinal epithelium cells (IECs). However, IEC proteins binding with Tsgal were not identified, and the mechanism by which Tsgal promotes larval invasion ...
Kai Ning Ma, Yao Zhang, Zhao Yu Zhang, Bo Ning Wang, Yan Yan Song, Lu Lu Han, Xin Zhuo Zhang, Shao Rong Long, Jing Cui, Zhong Quan Wang   +9 more
doaj   +1 more source