Results 81 to 90 of about 13,006,177 (289)
Journal of Education, Health and Sport, 2018 Currently, there are single data on the relationship between TLR-2 polymorphisms (Arg753Gln) and TLR-4 (Asp299Gly) polymorphisms and susceptibility to brucellosis.
Elchin Huseynov Mammad oglu
doaj +3 more sources
Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity
Advanced Science, EarlyView.Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang +11 more
wiley +1 more source
, 2014 Метою дослідження було вивчення ефективності вакцинації проти грипу в осіб із поліморфізмом Arg753Gln гену TLR-2, Leu412Phe TLR-3, Asp299Gly TLR-4. Провакциновано 66 осіб із мутантними генотипами та нормальним розподілом алелей TLR-2, TLR-3, TLR-4, віком
Руденко, Станіслав Станіславович +14 more
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Advanced Science, EarlyView.Amphiphilic sulfonated chitosan nanoparticles buffer endo/lysosomal acidity in microglia by limiting V‐ATPase membrane recruitment and restoring endosomal homeostasis. Following systemic administration, they accumulate in the ischemic hemisphere partly through association with infiltrating immune cells, suppress TLR3/IRF3 and TLR4/NF‐κB signaling ...
Xuanlin Wang +4 more
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Indian Journal of Animal Sciences, 2016 This study was conducted to observe the effects of dietary noni and kalmegh supplementation on production performance, immunity and gene expression of toll-like receptors in Nicobari fowl. Supplementation of noni and kalmegh significantly influenced the
JAI SUNDER, T SUJATHA, A RAJA, A KUNDU
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Advanced Science, EarlyView.Engineered Escherichia coli Nissle 1917 with a tannic acid‐mediated BPA coating enables tumor‐targeted boron delivery for BNCT. The low‐level incidental radiation generated during BNCT activate a RecA‐driven circuit to induce CXCL10, while radiation‐enhanced bacterial colonization triggers in situ vaccination and systemic antitumor immunity.
Yang Liu +11 more
wiley +1 more source
Research progress on ocular rosacea
Pifu-xingbing zhenliaoxue zazhiRosacea is a chronic inflammatory disease affecting the central face, with approximately 6% to 72% of patients experiencing ocular involvement. Ocular rosacea shares a similar pathogenesis with cutaneous rosacea, involving immune responses, neurovascular
WANG Xiaoyan, ZHANG Yingpeng
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Mechanisms by which interleukin-4 suppresses inflammatory cytokine production by activated human monocytes [PDF]
, 2011 Improving understanding of how inflammatory responses by monocytes and macrophages are regulated may aid in the development of more targeted therapies for chronic inflammatory disease.
Woodward, Eleanor
core
Self‐Assembling Peptide‐Adjuvant Conjugate (SaPAC) Platform for Precision Cancer Immunotherapy
Advanced Science, EarlyView.A self‐assembling peptide–adjuvant conjugate links neoantigens to TLR7 agonism, forming cationic nanoparticles that enhance lymph‐node retention, dendritic‐cell activation, and antitumor T‐cell immunity. This chemically defined platform shows how synchronized antigen and innate stimulation can be adapted across melanoma, bladder cancer, and triple ...
Yang‐Fan Wu +15 more
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Advanced Science, EarlyView.Helicobacter pylori infection induces sustained upregulation of the RNA‐binding protein IGF2BP1 in gastric epithelial cells, establishing a persistent epitranscriptomic program. IGF2BP1 stabilizes SLC7A11 mRNA in an m6A‐dependent manner to suppress ferroptosis and promote epithelial survival under oxidative stress. Pharmacological inhibition of IGF2BP1
Jing Ning +20 more
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