Results 21 to 30 of about 137,836 (151)

Acute Inflammation Is a Predisposing Factor for Weight Gain and Insulin Resistance

Pharmaceutics, 2022
In the course of infection and intense endotoxemia processes, induction of a catabolic state leading to weight loss is observed in mice and humans. However, the late effects of acute inflammation on energy homeostasis, regulation of body weight and ...
Edson Mendes de Oliveira, Jacqueline C. Silva, Thais P. Ascar, Silvana Sandri, Alexandre F. Marchi, Silene Migliorini, Helder T. I. Nakaya, Ricardo A. Fock, Ana Campa   +8 more
doaj   +1 more source

Toll-like receptor 2 induced senescence in intervertebral disc cells of patients with back pain can be attenuated by o-vanillin

Arthritis Research & Therapy, 2021
Background There is an increased level of senescent cells and toll-like teceptor-1, -2, -4, and -6 (TLR) expression in degenerating intervertebral discs (IVDs) from back pain patients.
Matthew Mannarino, Hosni Cherif, Li Li, Kai Sheng, Oded Rabau, Peter Jarzem, Michael H. Weber, Jean A. Ouellet, Lisbet Haglund   +8 more
doaj   +1 more source

Evaluation of Toll-Like receptor 2 and 4 RNA expression and the cytokine profile in postmenopausal women with metabolic syndrome. [PDF]

PLoS ONE, 2014
OBJECTIVE: To evaluate the gene expression of Toll-Like (TLR-2 and TLR-4) receptors and cytokine profile in postmenopausal women with or without metabolic syndrome (MetS).
Claudio Lera Orsatti, Eliana Aguiar Petri Nahas, Jorge Nahas-Neto, Fabio Lera Orsatti, Vanessa Innocenti Giorgi, Steven S Witkin   +5 more
doaj   +1 more source

Predictive value of systemic and local inflammation parameters in talc pleurodesis assessment

Biomedical Papers, 2015
Background: One option for the palliative treatment of recurrent malignant pleural effusion is powdered talc using thoracoscopy. This paper presents the results of selected systemic and local manifestations of the talc-induced inflammatory reaction using
Petr Habal, Nedal Omran, Karolina Jankovicova, Jan Krejsek, Jiri Mandak   +4 more
doaj   +1 more source

Pam3CSK4 enhances adaptive immune responses to recombinant Mycobacterium bovis bacille Calmette-Guérin expressing Plasmodium falciparum C-terminus merozoite surface protein-1

Asian Pacific Journal of Tropical Biomedicine, 2019
Objective: To determine the effects of toll-like receptor 2 (TLR-2) agonist, Pam3CSK4, on cellular and humoral immune response against recombinant Mycobacterium bovis bacille Calmette-Guérin (rBCG) expressing the C-terminus of merozoite surface protein-1
Mohamed H Abdikarim, Muhammad A Abbas, Munirah N Zakaria, Robaiza Zakaria, Rapeah Suppian   +4 more
doaj   +1 more source

Common variants in toll-like receptor family genes and risk of gastric cancer: a systematic review and meta-analysis

Frontiers in Genetics, 2023
Background: An increasing number of studies have suggested the relationship between single-nucleotide polymorphisms (SNPs) in toll-like receptor (TLR) genes and gastric cancer (GC) susceptibility; however, the available evidence is contradictory.
Ayoub Al Othaim, Sulieman Ibraheem Shelash Al-Hawary, Hashem O. Alsaab, Sami G. Almalki, Mazin A. A. Najm, Ahmed Hjazi, Ali Alsalamy, Abbas Firras Almulla, Hamzeh Alizadeh   +8 more
doaj   +1 more source

Single nucleotide polymorphisms of TLR-2, TLR-3, TLR-4 and susceptibility to inflammatory diseases of the respiratory tract

Zaporožskij Medicinskij Žurnal, 2018
The aim of the research is to establish an association between Arg753Gln polymorphism of TLR-2 gene, Leu412Phe of TLR-3 gene, Asp299Gly of TLR-4 gene and susceptibility to inflammatory diseases of the upper and lower respiratory tract and the complicated
N. O. Pryimenko, T. M. Kotelevska, H. M. Dubynska, I. P. Kaidashev, K. V. Pikul   +4 more
doaj   +1 more source

Zymosan attenuates melanoma growth progression, increases splenocyte proliferation and induces TLR-2/4 and TNF-α expression in mice

Journal of Inflammation, 2018
Background Melanoma is one of the most common types of skin malignancies. Since current therapies are suboptimal, considerable interest has focused on novel natural-based treatments.
Mehdi Taghavi, Esmaeil Mortaz, Alireza Khosravi, Ghasem Vahedi, Gert Folkerts, Mohammad Varahram, Mehdi Kazempour-Dizaji, Johan Garssen, Ian M. Adcock   +8 more
doaj   +1 more source

Aggregatibacter actinomycetemcomitans modulates toll-like receptors 2 and 4 in gingival epithelial cells in experimental periodontitis

Journal of International Clinical Dental Research Organization, 2010
Background: Periodontitis is a common bacterial infection precipitated by exaggerated host responses to the oral microorganisms, As the first cells to encounter the oral pathogens the gingival epithelial cells (GEC) respond via toll-like receptors (TLR ...
Mythily Srinivasan, Krithika N Kodumudi, Dominique M Galli   +2 more
doaj   +1 more source

Association of GT microsatellite polymorphism in TLR 2 gene with leprosy [PDF]

BMC Infectious Diseases, 2012
Background Toll-like receptor 2 (TLR2) is critical in bringing up immune responses to mycobacterial infections. The mutations in TLR2 are known to confer susceptibility for severe infection with mycobacteria. TLR2 may diminish response to mycobacterial proteins and place individuals at risk of developing leprosy.
Suryadevara NC, Sanjeev NV, Valluri Vijaya, Jain Suman, Anandraj MPJS   +4 more
openaire   +2 more sources