Results 41 to 50 of about 137,836 (151)

Polymorphisms IL10-819 and TLR-2 are potentially associated with sepsis in Brazilian patients [PDF]

Memórias do Instituto Oswaldo Cruz, 2010
Genetic variation in immune response is probably involved in the progression of sepsis and mortality in septic patients. However, findings in the literature are sometimes conflicting or their significance is uncertain. Thus, we investigated the possible association between 12 polymorphisms located in the interleukin-6 (IL6), IL10, TLR-2, Toll-like ...
Carregaro, Fernanda, Carta, Adriana, Cordeiro, José Antônio, Lobo, Suzana M., da Silva, Eloiza H. Tajara, Leopoldino, Andréia M.   +5 more
openaire   +4 more sources

Patterns of milk productivity associated with biochemical parameters and expressions of the HSPs and Toll Like genes in dairy buffaloes

Medicina Veterinária
The aim of this study was to verify milk productivity associated with biochemical parameters and expression of stress marker genes (HSP70, HSP90?, HSP90?) and immunity (TLR-2 and TLR-4) in dairy buffaloes.
Henrique Low Nogueira, Elem Cristina Macedo Barra de Sousa, Cintia Luana Pinheiro Santos, Ednaldo Silva Filho, Priscila Di Paula Bessa Santana   +4 more
doaj   +5 more sources

Toll-Like Receptor-1 and Receptor-2 and Beta-Defensin in Postcholecystectomy Bile Duct Injury

Gastroenterology Research and Practice, 2015
Postcholecystectomy bile duct injuries (BDI) produce hepatic cholestasis and cause infection of the biliary tract. The biliary cells participate in secreting cytokines and in expression of immune response receptors.
Alejandra Guillermina Miranda-Díaz, José Manuel Hermosillo-Sandoval, Martha Arisbeth Villanueva-Pérez, Luis Miguel Román-Pintos, Trinidad García-Iglesias, Adolfo Daniel Rodríguez-Carrizalez, Ernesto Germán Cardona-Muñoz   +6 more
doaj   +1 more source

Coxiella burnetii lipopolysaccharide blocks p38α-MAPK activation through the disruption of TLR-2 and TLR-4 association

Frontiers in Cellular and Infection Microbiology, 2015
To survive in macrophages, Coxiella burnetii hijacks the activation pathway of macrophages. Recently, we have demonstrated that C. burnetii, via its lipopolysaccharide (LPS), avoids the activation of p38α-MAPK through an antagonistic engagement of Toll ...
Filippo eConti, Nicolas eBoucherit, Veronica eBaldassarre, Virginie eTrouplin, Giovanna eMottola, Rudolf eToman, Jean-louis eMege, Eric eGhigo   +7 more
doaj   +1 more source

Polyethylene wear particles induce TLR 2 upregulation in the synovial layer of mice

Journal of Materials Science: Materials in Medicine, 2013
A cellular and receptor mediated response to ultra-high-molecular-weight-polyethylene (UHMWPE) wear particles results in a release of proinflammatory cytokines and induces an inflammatory reaction causing osteolysis in total joint replacement. This investigation offers insight into the toll-like receptor (TLR) mediated activation by polyethylene wear ...
A C, Paulus, J, Frenzel, A, Ficklscherer, B P, Roßbach, C, Melcher, V, Jansson, S, Utzschneider   +6 more
openaire   +2 more sources

Placental Trophoblast Responses to Porphyromonas gingivalis Mediated by Toll-like Receptor-2 and -4

Journal of Dentistry Indonesia, 2013
Trophoblast participates in preventing allorecognition and controlling pathogens that compromise fetal wellbeing. Toll-like receptors recognize conserved sequences on the pathogens surface and trigger effector cell functions.
Banun Kusumawardani, Marsetyawan HNE Soesatyo, Djaswadi Dasuki, Widya Asmara   +3 more
doaj   +1 more source

Overexpression of proinflammatory TLR-2-signalling lipoproteins in hypervirulent mycobacterial variants.

Cellular microbiology, 2011
Changes in the cell envelope composition of mycobacteria cause major changes in cytokine profiles of infected antigen presenting cells. We describe here the modulation of inflammatory responses by Mycobacterium abscessus, an emerging pathogen in cystic fibrosis. M. abscessus is able to switch from a smooth (S) to a rough (R) morphotype by the loss of a
Roux, Anne-Laure, Ray, Aurélie, Pawlik, Alexandre, Medjahed, Halima, Etienne, Gilles, Rottman, Martin, Catherinot, Emilie, Coppée, Jean-Yves, Chaoui, Karima, Monsarrat, Bernard, Toubert, Antoine, Daffé, Mamadou, Puzo, Germain, Gaillard, Jean-Louis, Brosch, Roland, Dulphy, Nicolas, Nigou, Jérôme, Herrmann, Jean-Louis   +17 more
openaire   +3 more sources

Gut Microbiota Is a Key Modulator of Insulin Resistance in TLR 2 Knockout Mice

PLoS Biology, 2011
Environmental factors and host genetics interact to control the gut microbiota, which may have a role in the development of obesity and insulin resistance. TLR2-deficient mice, under germ-free conditions, are protected from diet-induced insulin resistance.
Andréa M Caricilli, Paty K Picardi, Lélia L de Abreu, Mirian Ueno, Patrícia O Prada, Eduardo R Ropelle, Sandro Massao Hirabara, Ângela Castoldi, Pedro Vieira, Niels O S Camara, Rui Curi, José B Carvalheira, Mário J A Saad   +12 more
openaire   +4 more sources

Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis

BMC Gastroenterology, 2010
Background Previously we reported that mice deficient in toll-like receptor 4 (TLR-4) signalling were protected from diet-induced non-alcoholic steatohepatitis (NASH).
Brady Kristen, Pang Jia, Allman Monique, Gaskin LaTausha, Rivera Chantal A, Adegboyega Patrick, Pruitt Kevin   +6 more
doaj   +1 more source

Trichinella spiralis galectin binding to toll-like receptor 4 induces intestinal inflammation and mediates larval invasion of gut mucosa

Veterinary Research, 2023
Previous studies showed that Trichinella spiralis galectin (Tsgal) facilitates larval invasion of intestinal epithelium cells (IECs). However, IEC proteins binding with Tsgal were not identified, and the mechanism by which Tsgal promotes larval invasion ...
Kai Ning Ma, Yao Zhang, Zhao Yu Zhang, Bo Ning Wang, Yan Yan Song, Lu Lu Han, Xin Zhuo Zhang, Shao Rong Long, Jing Cui, Zhong Quan Wang   +9 more
doaj   +1 more source