Effects of Separate and Concomitant TLR-2 and TLR-4 Activation in Peripheral Blood Mononuclear Cells of Newborn and Adult Horses. [PDF]
PLoS ONE, 2013 Deficient innate and adaptive immune responses cause newborn mammals to be more susceptible to bacterial infections than adult individuals. Toll-like receptors (TLRs) are known to play a pivotal role in bacterial recognition and subsequent immune ...
Johannes Cornelis Vendrig +2 more
doaj +17 more sources
Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis [PDF]
BMC Gastroenterology, 2010 Background Previously we reported that mice deficient in toll-like receptor 4 (TLR-4) signalling were protected from diet-induced non-alcoholic steatohepatitis (NASH).
Brady Kristen +6 more
doaj +3 more sources
Differences in the Expression of TLR-2, NOD2, and NF-κB in Placenta Between Twins. [PDF]
Arch Immunol Ther Exp (Warsz), 2018 Dizygotic twins share the same type of genetic relationship as non-twin siblings. Whereas monozygotic (MZ) twins are considered to have identical genetic material, they still differ. There is a number of reasons for early MZ twin discordance, including differences in the in utero environment, stochasticity, genetic mosaicism, and epigenetic factors ...
Szylberg Ł +6 more
europepmc +4 more sources
Direct and indirect effects of synthetic dual TLR-2 and TLR-7 agonists (Dual TLR-2/7) on latent HIV
Journal of Virus Eradication, 2017 A.B. Macedo +7 more
doaj +2 more sources
Differential profiles of soluble and cellular toll like receptor (TLR)-2 and 4 in chronic periodontitis. [PDF]
PLoS ONE, 2018 Chronic periodontitis is a common inflammatory disease initiated by a complex microbial biofilm and mediated by the host response causing destruction of the supporting tissues of the teeth. Host recognition of pathogens is mediated by toll-like receptors
Hawra AlQallaf +5 more
doaj +2 more sources
Analysis of Expression and Localization of TLR-2 by Immunofluorescent Technique in Healthy and Inflammed Oral Tissues [PDF]
Journal of Clinical and Diagnostic Research, 2013 Introduction: Toll-like receptors (TLRs) are an important component of immune system. Among them, TLR-2 plays a dominant role in the oral tissues in initiating inflammation in chronic periodontitis.
Romaldin S. D’souza +5 more
doaj +1 more source
Dialyzable Leukocyte Extracts Activate TLR-2 on Monocytes [PDF]
Natural Product Communications, 2014 Dialyzable leukocyte extracts (DLE) transfer specific cell-mediated immune responses from sensitized donors to non-immune recipients. In addition, DLE have several immunomodulatory effects and are used for the treatment of several infectious and non-infectious diseases. Previous studies showed that human DLE obtained from virus-infected leukocytes and
Uriel, García-Hernández +10 more
openaire +2 more sources
International Journal of Mycobacteriology, 2023 Background: It has been demonstrated that toll-like receptors (TLR2), TLR4, and TLR9 which were initially known for recognizing bacterial products are involved in the detection of viral components.
Gaurav Kaushik, Richa Vashishtha
doaj +1 more source
CD47 and TLR-2 Cross-Talk Regulates Neutrophil Transmigration [PDF]
The Journal of Immunology, 2009 Abstract Neutrophil (PMN) infiltration into tissues is a hallmark of acute inflammation and is crucial for the rapid removal of microbial pathogens. Previous studies have shown that PMN transmigration is regulated by the cell surface protein CD47.
Alex C, Chin +5 more
openaire +2 more sources
Assessment of the immunomodulatory properties of the probiotic strain Lactobacillus paracasei K5 in vitro and in vivo [PDF]
, 2020 Lactobacillus paracasei K5 is a lactic acid bacteria (LAB) strain that has been isolated from dairy products. Previous studies have established its probiotic potential in a series of in vitro tests, including molecular characterization, safety profiling,
Alexopoulos, Athanasios +9 more
core +2 more sources