Results 311 to 320 of about 156,491 (330)
TLR2 c.374C>T variant linked to natural resistance against brucellosis in Italian Mediterranean river buffalo. [PDF]
Fulgione A +6 more
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JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 1, Page 98-100, January 2026.
Sven‐Niklas Burmann +5 more
wiley +1 more source
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Science Signaling, 2021
TLR2 located in the endothelium promotes angiogenesis and inflammation.
Samantha Mahfoud, Tatiana V. Petrova
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TLR2 located in the endothelium promotes angiogenesis and inflammation.
Samantha Mahfoud, Tatiana V. Petrova
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TLR2 in murine atherosclerosis
Seminars in Immunopathology, 2007Atherosclerosis was once thought to be solely a disease of lipid accumulation in the vessel wall. It does involve lipid accumulation, but inflammation appears to be an important driving factor. Consequently, our laboratory undertook to examine the role(s) of TLRs, and especially TLR2, in murine models of atherosclerosis.
Peter S, Tobias, Linda K, Curtiss
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Immunology, 2023
AbstractLeishmania donovani, a protozoan parasite, resides and replicates in macrophages and inflicts the potentially fatal disease visceral leishmaniasis (VL). The parasite‐expressed surface lipophosphoglycan (LPG) was implicated in binding TLR2 on NK cells, but the modus operandi of its disease‐promoting influence remained unknown.
Soumya Kanti Ghosh +6 more
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AbstractLeishmania donovani, a protozoan parasite, resides and replicates in macrophages and inflicts the potentially fatal disease visceral leishmaniasis (VL). The parasite‐expressed surface lipophosphoglycan (LPG) was implicated in binding TLR2 on NK cells, but the modus operandi of its disease‐promoting influence remained unknown.
Soumya Kanti Ghosh +6 more
openaire +2 more sources
Rare TLR2 mutations reduce TLR2 receptor function and can increase atopy risk
Allergy, 2009Background: Common genetic variations in toll‐like receptor 2 (TLR2), an innate pathogen recognition receptor, may influence the development of atopic diseases. So far, very little is known about the role of rare TLR2 mutations in these diseases.Objective: We investigated the functional properties of six rare amino acid changes in TLR2 (and one amino
M S D, Kormann +9 more
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Molecular Genetics, Microbiology and Virology, 2009
Various strains of mycoplasmas cause activation of transcriptional factor NF-kB as a result of interaction with different combinations of Toll-like receptors (TLR). It is well known that the MALP-2 protein of M. fermentans activates the NF-kB through interaction with the TLR2/6, lipid-associated membrane lipopeptides (LAMPs) of M. penetrans through the
D Iu, Logunov +7 more
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Various strains of mycoplasmas cause activation of transcriptional factor NF-kB as a result of interaction with different combinations of Toll-like receptors (TLR). It is well known that the MALP-2 protein of M. fermentans activates the NF-kB through interaction with the TLR2/6, lipid-associated membrane lipopeptides (LAMPs) of M. penetrans through the
D Iu, Logunov +7 more
openaire +2 more sources
The Journal of Immunology, 2016
Abstract TLR2 expression is enhanced in MS and EAE, but its role in these diseases is controversial. In adoptive transfer EAE, exogenous TLR ligands are not administered yet TLR2-deficient mice have been reported to develop attenuated disease. Despite this evidence for a disease-promoting function of TLR2, others have shown the opposite,
Emily J Anstadt +3 more
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Abstract TLR2 expression is enhanced in MS and EAE, but its role in these diseases is controversial. In adoptive transfer EAE, exogenous TLR ligands are not administered yet TLR2-deficient mice have been reported to develop attenuated disease. Despite this evidence for a disease-promoting function of TLR2, others have shown the opposite,
Emily J Anstadt +3 more
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The Journal of Immunology, 2012
Abstract TLR2 senses lipoproteins expressed by Gram positive bacteria, mycoplasma, mycobacteria and fungi. The Arg753Gln (R753Q) polymorphism in the TIR domain of TLR2 has been linked to increased incidence of tuberculosis, leprosy and other diseases. But the molecular mechanisms by which it affects TLR2 functions are unclear. We studied
Yanbao Xiong +2 more
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Abstract TLR2 senses lipoproteins expressed by Gram positive bacteria, mycoplasma, mycobacteria and fungi. The Arg753Gln (R753Q) polymorphism in the TIR domain of TLR2 has been linked to increased incidence of tuberculosis, leprosy and other diseases. But the molecular mechanisms by which it affects TLR2 functions are unclear. We studied
Yanbao Xiong +2 more
openaire +1 more source

