Results 311 to 320 of about 156,491 (330)

TLR2 c.374C>T variant linked to natural resistance against brucellosis in Italian Mediterranean river buffalo. [PDF]

open access: yesBMC Vet Res
Fulgione A   +6 more
europepmc   +1 more source

Leukemia cutis with concomitant acrodermatitis chronica atrophicans and chronic B‐cell lymphocytic leukemia: complete clearance under doxycycline therapy

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 1, Page 98-100, January 2026.
Sven‐Niklas Burmann   +5 more
wiley   +1 more source
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The double life of TLR2

Science Signaling, 2021
TLR2 located in the endothelium promotes angiogenesis and inflammation.
Samantha Mahfoud, Tatiana V. Petrova
openaire   +2 more sources

TLR2 in murine atherosclerosis

Seminars in Immunopathology, 2007
Atherosclerosis was once thought to be solely a disease of lipid accumulation in the vessel wall. It does involve lipid accumulation, but inflammation appears to be an important driving factor. Consequently, our laboratory undertook to examine the role(s) of TLRs, and especially TLR2, in murine models of atherosclerosis.
Peter S, Tobias, Linda K, Curtiss
openaire   +2 more sources

Leishmania surface molecule lipophosphoglycan‐TLR2 interaction moderates TPL2‐mediated TLR2 signalling for parasite survival

Immunology, 2023
AbstractLeishmania donovani, a protozoan parasite, resides and replicates in macrophages and inflicts the potentially fatal disease visceral leishmaniasis (VL). The parasite‐expressed surface lipophosphoglycan (LPG) was implicated in binding TLR2 on NK cells, but the modus operandi of its disease‐promoting influence remained unknown.
Soumya Kanti Ghosh   +6 more
openaire   +2 more sources

Rare TLR2 mutations reduce TLR2 receptor function and can increase atopy risk

Allergy, 2009
Background:  Common genetic variations in toll‐like receptor 2 (TLR2), an innate pathogen recognition receptor, may influence the development of atopic diseases. So far, very little is known about the role of rare TLR2 mutations in these diseases.Objective:  We investigated the functional properties of six rare amino acid changes in TLR2 (and one amino
M S D, Kormann   +9 more
openaire   +2 more sources

Lipid-associated membrane lipopeptides of M. arginini activate NF-κB by interacting with TLR2/1, TLR2/6, and TLR2/CD14

Molecular Genetics, Microbiology and Virology, 2009
Various strains of mycoplasmas cause activation of transcriptional factor NF-kB as a result of interaction with different combinations of Toll-like receptors (TLR). It is well known that the MALP-2 protein of M. fermentans activates the NF-kB through interaction with the TLR2/6, lipid-associated membrane lipopeptides (LAMPs) of M. penetrans through the
D Iu, Logunov   +7 more
openaire   +2 more sources

TLR2 tolerance in EAE

The Journal of Immunology, 2016
Abstract TLR2 expression is enhanced in MS and EAE, but its role in these diseases is controversial. In adoptive transfer EAE, exogenous TLR ligands are not administered yet TLR2-deficient mice have been reported to develop attenuated disease. Despite this evidence for a disease-promoting function of TLR2, others have shown the opposite,
Emily J Anstadt   +3 more
openaire   +1 more source

R753Q polymorphism compromises TLR2 signaling functions by altering TLR6-TLR2 hetero-dimerization, TLR2 tyrosine phosphorylation and MyD88 recruitment (180.2)

The Journal of Immunology, 2012
Abstract TLR2 senses lipoproteins expressed by Gram positive bacteria, mycoplasma, mycobacteria and fungi. The Arg753Gln (R753Q) polymorphism in the TIR domain of TLR2 has been linked to increased incidence of tuberculosis, leprosy and other diseases. But the molecular mechanisms by which it affects TLR2 functions are unclear. We studied
Yanbao Xiong   +2 more
openaire   +1 more source

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