Results 321 to 330 of about 156,491 (330)

Megakaryocyte TLR2: immunity bullet?

Blood, 2011
Innate immunity is the host defensive weapon against pathogens and this issue of Blood offers an interesting new bullet for the immune system gun by studying the role of Toll-like receptor 2 (TLR2) in megakaryocytic function; a field previously not explored.
PIGNATELLI, Pasquale, CARNEVALE, Roberto
openaire   +2 more sources

TLR2 Arg677Trp polymorphism in leprosy: revisited

Human Genetics, 2005
We investigated the Toll-like receptor 2 (TLR2) Arg677Trp polymorphism, associated with lepromatous leprosy in the Korean population and shown to abrogate TLR2-mediated signalling in response to mycobacterial ligands, in 286 Indian leprosy patients and 183 ethnically matched controls.
Dheeraj, Malhotra, Vineet, Relhan, B S N, Reddy, Ramesh, Bamezai   +3 more
openaire   +2 more sources

TLR2 joins the interferon gang

Nature Immunology, 2009
The induction of type I interferon is a critical checkpoint in antiviral immunity. Toll-like receptor 2 can unexpectedly induce type I interferon in the subset of inflammatory monocytes during infection with vaccinia virus.
Franz Bauernfeind, Veit Hornung
openaire   +1 more source

TLR2 agonists and their structure–activity relationships

Organic & Biomolecular Chemistry, 2020
We review the structure–activity relationships and synthetic studies of TLR2 agonists – important chemical targets in immunotherapy.
Benjamin L. Lu, Geoffrey M. Williams, Margaret A. Brimble   +2 more
openaire   +2 more sources

The Noninflammatory Side of TLR2

Science Signaling, 2012
Toll-like receptor 2 promotes tumorigenesis in a mouse model of gastric cancer, but not by enhancing inflammation.
openaire   +1 more source

TLR2 Stimulates Th1 Effector Functions

Science's STKE, 2007
Toll-like receptors (TLRs) are pattern-recognition receptors that recognize microbial products and are crucial components of the innate immune system. TLR ligands have costimulatory roles with stimulation of the T cell antigen receptor (TCR) of naïve CD4 + T cells (although TLR ligands alone cannot stimulate naïve
openaire   +1 more source

Does TLR2 regulate intestinal inflammation?

European Journal of Immunology, 2010
AbstractThere is almost no aspect of the immune response that is not regulated by TLR. Initially described as drivers of the innate immune response to pathogens, it is now clear that the TLR family can also influence most aspects of adaptive immunity, as well as determine how tissue cells interact with microbes in their environment.
openaire   +2 more sources

??????????????? ?????????????????????????? ?????????? TLR2 ???? TLR4 ???? ???????????????????? ???? ?????????????? ???????????????????????????? ????????????????

2014
???????????????????? ?????????????????????? ???????????????????????????????? ?????????????????????? ?????????????????? Arg753Gln ???????? TLR2 ???? Asp299Gly, Thr399Ile ???????? TLR4 ?????????? ????????, ???? ???????????????????? ?? ?????????????????????? ??????????????, ?? ?????????? ??????????????? ?????????????????????????? ???? ?????????????????? ??
openaire   +1 more source

TLR2 Gene

2020
openaire   +1 more source

Signalling: New roles for TLR2.

Nature reviews. Cancer, 2013
openaire   +2 more sources