Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley +1 more source
S100A4 Induces Neutrophilic Inflammation in Chronic Rhinosinusitis with Nasal Polyps via TLR4 Pathway. [PDF]
Tu Y +10 more
europepmc +1 more source
Role of Exogenous HSPB1 in Cytokine Regulation Through TLR2, TLR4, TLR5, TLR7, and MyD88/MAPK p38/NF-κB Pathways in Differentiated THP-1 Cells [PDF]
Rajah Khaouader Essalemi +4 more
openalex +1 more source
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley +1 more source
Exploratory study on the efficacy of Lingze mixture in gouty arthritis rats and preliminary analysis of its potential mechanisms via transcriptome sequencing. [PDF]
Liu J +15 more
europepmc +1 more source
Effect of Chitosan Oligosaccharide (COS) Supplementation on TLR4 Gene Expression, Blood Profil, and Carcass Weight in Broiler Chicken [PDF]
Muhammad Pramujo +3 more
openalex +1 more source
The role of cytokines in ovarian cancer drug resistance
Abstract Ovarian cancer is the leading cause of death among women diagnosed with female reproductive system cancers. While significant advances have been made in treating various types of cancer, progress in ovarian cancer treatment over the past 20 years has been minimal, and the treatment course of ovarian cancer is not linear. Although many patients
Lu Wang +7 more
wiley +1 more source
Multiple Signaling Axes (TNF-α/IL1β/IL8, TLR4/MYD88/NF-κB, and TGF-β1/ROS) Associated With Coronary Collateral Circulation of Coronary Chronic Total Occlusion in Geriatric Patients. [PDF]
Zhao Y, Zhou H, Chen Y, Guo D.
europepmc +1 more source

