Results 321 to 330 of about 274,305 (384)

Pre‐diagnostic immunological markers of bacterial translocation and liver cancer risk: A nested case–control analysis of 12 prospective cohorts

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Disruption of the gut–liver axis has been suggested to play an important role in liver carcinogenesis. However, limited prospective research has explored associations between potentially harmful gut‐derived bacterial products and liver cancer risk.
Cody Z. Watling   +36 more
wiley   +1 more source

Immunometabolic Features and Key Biomarkers in Lung Cancer Complicated by Pulmonary Tuberculosis: Insights From Transcriptome and Clinical Cohort Analysis

open access: yesiMetaMed, EarlyView.
Integrative analysis of LC‐PTB patients pinpoints six biomarkers (ANK2, EPB42, CA1, HBB, HBD, MYL4) that reshape the immune microenvironment, offering new targets for diagnosis and treatment of lung cancer complicated by tuberculosis. ABSTRACT Coexisting lung cancer and pulmonary tuberculosis (LC‐PTB) is clinically challenging in diagnosis and ...
Ling Yang   +10 more
wiley   +1 more source

Potassium Sorbate Triggers Kidney Injury via Dysregulated Intercellular Communication: A Study Combining Network Toxicology, Machine Learning, Molecular Docking, and Single‐Cell RNA Sequencing

open access: yesiMetaMed, EarlyView.
Amyloid precursor protein (APP)‐mediated endothelial‐immune cell crosstalk is a novel mechanism for potassium sorbate‐induced renal injury. Multi‐omics integration (network toxicology, machine learning, scRNA‐seq) uncovers this interaction via APP‐CD74/PTGER2 axes, linking oxidative stress and inflammation to renal damage. ABSTRACT Acute kidney injury (
Yimao Wu   +5 more
wiley   +1 more source

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