Tlr5 - Open Access .click

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TLR5 is not required for flagellin-mediated exacerbation of DSS colitis

Inflammatory Bowel Diseases, 2010
The two forms of human inflammatory bowel disease, Crohn's disease (CD) and ulcerative colitis (UC), are both associated with loss of tolerance to gut microbial antigens. The dominant antigen recognized by antibody and T-cell responses in patients with CD is bacterial flagellin. Flagellin is also the only known ligand for Toll-like receptor 5 (TLR5), a
Sabine M, Ivison +6 more
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TLR5 takes aim at bacterial propeller

Nature Immunology, 2003
The Toll-like receptor (TLR) family targets pathogen-derived molecules in regions unlikely to change under selection pressures. For TLR5, which recognizes the protein flagellin, the function of the targeting motif is key.
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Cyprinid‐specific duplicated membrane TLR5 senses dsRNA as functional homodimeric receptors

EMBO Reports, 2022
Zhiwei Liao, Chunrong Yang, Yong-An Zhang +2 more
exaly

TLR5

2012
Shaikh M. Atif, Stephen J. McSorley
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Roseburia intestinalis and Its Metabolite Butyrate Inhibit Colitis and Upregulate TLR5 through the SP3 Signaling Pathway

Nutrients, 2022
Minjia Chen, Yuting Tian, Linling Lv
exaly

TLR5 recognizes Aeromonas hydrophila flagellin and interacts with MyD88 in Nile tilapia

Developmental and Comparative Immunology, 2022
Fengying Gao, Maixin Lu, Zhigang Liu
exaly

TLR5 wt Allele

2020
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Amino acids 89–96 of Salmonella typhimurium flagellin represent the major domain responsible for TLR5-independent adjuvanticity in the humoral immune response

Cellular and Molecular Immunology, 2014
Xilong Kang, Xinan Jiao, Pan Zhiming
exaly