Metabolic Regulatory Mechanism of Gastric Motility by Acetylcholine. [PDF]
Gastroenterology ResLee JY +14 more
europepmc +1 more source
Review of the clinical electrooculogram - Part 1: Mechanism of the Light-Rise. [PDF]
Doc OphthalmolConstable PA +3 more
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The function of chloride channels in digestive system disease (Review). [PDF]
Int J Mol MedHu Y, Tuo B.
europepmc +1 more source
Unravelling the Role of Post-Junctional M2 Muscarinic Receptors in Cholinergic Nerve-Mediated Contractions of Airway Smooth Muscle. [PDF]
Int J Mol SciGhosh S +4 more
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The nonexcitable smooth muscle: remodeling the smooth muscle ion transport toolkit in disease. [PDF]
Physiol RevJohnson MT, Trebak M.
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Antiinflammatory Therapy in Bronchiectasis: Successes, Failures, and a Call for a More Precise Approach. [PDF]
ChestJia S.
europepmc +1 more source
The multifaceted role of TMEM16A in cancer [PDF]
Cell Calcium, 2019 The calcium-activated chloride channel TMEM16A is intimately linked to cancers. Over decades, TMEM16A over-expression and contribution to prognosis have been widely studied for multiple cancers strengthening the idea that TMEM16A could be a valuable biomarker and a promising therapeutic target.
David Crottès, Lily Jan
exaly +8 more sources
TMEM16A Mediates Mucus Production in Human Airway Epithelial Cells
American Journal of Respiratory Cell and Molecular Biology, 2021 TMEM16A is a Ca2+-activated chloride channel that was shown to enhance production and secretion of mucus in inflamed airways. It is, however, not clear whether TMEM16A directly supports mucus production, or whether mucin and TMEM16A are upregulated ...
Karl Kunzelmann +2 more
exaly +2 more sources
Pharmacological characterization of TMEM16A currents [PDF]
Channels, 2014 Recent studies have shown that transmembrane protein 16 A (TMEM16A) is a subunit of calcium-activated chloride channels (CACCs). Pharmacological agents have been used to probe the functional role of CACCs, however their effect on TMEM16A currents has not been systematically investigated.
Gérard Sergeant +2 more
exaly +3 more sources
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Emerging Modulators of TMEM16A and Their Therapeutic Potential
Journal of Membrane Biology, 2021Calcium-activated chloride channels (CaCCs) are widespread chloride channels which rely on calcium activation to perform their functions. In 2008, TMEM16A (also known as anoctamin1, ANO1) was identified as the molecular basis of the CaCCs, which provided the possibility to study the physiological function of CaCCs.
Xuzhao Wang, Yafei Chen, Hailong An
exaly +3 more sources