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Mucus Release and Airway Constriction by TMEM16A May Worsen Pathology in Inflammatory Lung Disease [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
Activation of the Ca2+ activated Cl- channel TMEM16A is proposed as a treatment in inflammatory airway disease. It is assumed that activation of TMEM16A will induce electrolyte secretion, and thus reduce airway mucus plugging and improve mucociliary ...
Karl Kunzelmann   +2 more
exaly   +2 more sources
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TMEM16A channel upregulation in arterial smooth muscle cells produces vasoconstriction during diabetes

American Journal of Physiology - Heart and Circulatory Physiology, 2021
Dennis Leo   +2 more
exaly  

Ca-activated Cl channel TMEM16A inhibition by cholesterol promotes angiogenesis in endothelial cells

Journal of Advanced Research, 2021
Qinghuan Xiao, Shuya Luo, Lichuan Bai
exaly  

Pharmacological Inhibition and Activation of the Ca2+ Activated Cl− Channel TMEM16A

International Journal of Molecular Sciences, 2020
Karl Kunzelmann   +2 more
exaly  

Recent advances in TMEM16A: Structure, function, and disease

Journal of Cellular Physiology, 2019
Xuzhao Wang, Yafei Chen, Hailong An
exaly  

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