Results 91 to 100 of about 41,790 (304)

F‐Type Pyocin Versus Phage λ Tail: Conserved Hub, Divergent Fibers

Advanced Science, EarlyView.
Near‐atomic cryo‐EM structures of a Gram‐negative F‐type pyocin reveal a conserved tail tip architecture shared with bacteriophage λ together with a previously unrecognized side‐fiber attachment mode. These findings provide new insight into tailocin assembly and host recognition and establish a structural framework for engineering precision ...
Zhiwei Gu, Yufan Xie, Lanxin Wang, Luyan Ma, Xiaofei Ge, Jiawei Wang   +5 more
wiley   +1 more source

Trimethoprim-sulfamethoxazole (TMP/SMX) potentiates indinavir nephrotoxicity [PDF]

, 2002
Objectives: Indinavir is a widely prescribed protease inhibitor in the treatment of HIV infection. It has been associated with nephrolithiasis, crystalluria and tubulointerstitial nephritis.
Araujo, Magali de [UNIFESP], Seguro, Antonio Carlos   +1 more
core  

Microemulsion-based novel transdermal delivery system of tetramethylpyrazine: preparation and evaluation in vitro and in vivo

International Journal of Nanomedicine, 2011
Ji-Hui Zhao, Li Ji, Hui Wang, Zhi-Qiang Chen, Yong-Tai Zhang, Ying Liu, Nian-Ping FengSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of ChinaObjective: To deliver 2,3,5,6-tetramethylpyrazine ...
Zhao JH, Ji L, Wang H, Chen ZQ, Zhang YT, Liu Y, Feng NP   +6 more
doaj  

Synthesis, Characterization, and Evaluation of the Antimicrobial Effects and Cytotoxicity of a Novel Nanocomposite Based on Polyamide 6 and Trimetaphosphate Nanoparticles Decorated with Silver Nanoparticles

Antibiotics
This study aimed to develop a polymeric matrix of polyamide-6 (P6) impregnated with trimetaphosphate (TMP) nanoparticles and silver nanoparticles (AgNPs), and to evaluate its antimicrobial activity, surface free energy, TMP and Ag+ release, and ...
Leonardo Antônio de Morais, Francisco Nunes de Souza Neto, Thayse Yumi Hosida, Danilo Martins dos Santos, Bianca Carvalho de Almeida, Elisabete Frollini, Sergio Paulo Campana Filho, Debora de Barros Barbosa, Emerson Rodrigues de Camargo, Alberto Carlos Botazzo Delbem   +9 more
doaj   +1 more source

Intra-articular delivery of tetramethylpyrazine microspheres with enhanced articular cavity retention for treating osteoarthritis

Asian Journal of Pharmaceutical Sciences, 2018
Tetramethylpyrazine (TMP) is a traditional Chinese herbal medicine with strong anti-inflammatory and cartilage protection activities, and thus a promising candidate for treating osteoarthritis.
Xiuping Zhang, Yang Shi, Zhiyue Zhang, Zhenlei Yang, Guihua Huang   +4 more
doaj   +1 more source

The new perspective of old antibiotic: In vitro antibacterial activity of TMP-SMZ against Klebsiella pneumoniae

Journal of Microbiology, Immunology and Infection, 2020
Background/purpose: Trimethoprim-sulfamethoxazole (TMP-SMZ) is broadly administered to treat multiple infections, and the paucity of effective treatment alternatives for infections caused by Klebsiella pneumoniae has led to a renewed interest in TMP-SMZ.
Jiahui Li, Wenzi Bi, Guofeng Dong, Yizhi Zhang, Qing Wu, Tongyu Dong, Jianming Cao, Tieli Zhou   +7 more
doaj   +1 more source

A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair

Advanced Science, EarlyView.
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong, Minhao Liu, Mingming Zheng, Jizhou Jia, Ziyan Zhu, Guang Kong, Jie Liu, Juan Wang, Wenbo Li, Qingyuan Wang, Qian Zhu, Peiran Chan, Tao Qin, Jiayang Wu, Yongjie Zhang, Chunming Tang, Cong Li, Jin Fan   +17 more
wiley   +1 more source

Photocatalytic Recovery of Aromatic Chemicals from Waste Plastics

Advanced Science, EarlyView.
This Review summarizes recent advances in the photocatalytic recovery of aromatic chemicals from plastic waste, with emphasis on fundamental mechanism, representative catalytic systems, and future challenges and development directions, which is expected to provide in‐depth and valuable insights and references into the key role of sustainable catalysis ...
Lizhen Liu, Jutarat Jitrada, Jun Huang
wiley   +1 more source

Second-Generation Covalent TMP-Tag for Live Cell Imaging [PDF]

, 2016
Chemical tags are now viable alternatives to fluorescent proteins for labeling proteins in living cells with organic fluorophores that have improved brightness and other specialized properties. Recently, we successfully rendered our TMP-tag covalent with
Sarah S. Gallagher (2051935), Michael P. Sheetz (269661), Zhixing Chen (1303152), Chaoran Jing (1923076), Virginia W. Cornish (1265385)   +4 more
core   +1 more source

Investigation on Synthesis of Trimethylolpropane (TMP) Ester from Non-edible Oil

Bulletin of Chemical Reaction Engineering & Catalysis, 2020
Trimethylolpropane (TMP) ester is an eco-friendly lubricant that fully biodegradable and known as bio lubricant. In this study, TMP ester was produced from waste cooking oil and rubber seed oil through a two-step synthesis approach.
Nurazreen Shazwin Kamarudin, Harumi Veny, Nailah Fasihah Sidek, Faisal Abnisa, Rozana Azrina Sazali, Noorhaliza Aziz   +5 more
doaj   +1 more source