Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2594-2614, April 2026.Abstract Glucocorticoids (GCs) are widely utilised for the treatment of inflammatory and autoimmune conditions but often precipitate significant hyperglycaemia. People with type 1 diabetes (PWT1D) may be particularly affected due to the challenges of adjusting insulin dosing, for which recommendations remain unclear.
Alexandra Katz +8 more
wiley +1 more source
Chemical Proteomics Identifies Ketogenesis‐Mediated Cysteine Modifications Regulating Redox Function
Angewandte Chemie, Volume 138, Issue 14, 27 March 2026.Herein, we report ketone body induce cysteine modifications beyond lysine acylation, as revealed by integrating chemical proteomics with open‐search methods. Among the modifications, cysteine crotonation (Ccr) was chemically validated by endogenous peptide‐based co‐elution assays.
Yuan‐Fei Zhou +8 more
wiley +2 more sources
Photocontrolled trimethoprim PROTACs targeting the eDHFR protein tag. [PDF]
Nat CommunSharma N +9 more
europepmc +1 more source
International Journal of Urology, Volume 33, Issue 4, April 2026.ABSTRACT Objectives To compare the effectiveness and safety of two antibiotic prophylaxis regimens, ciprofloxacin plus gentamicin and ceftriaxone plus cefixime, in preventing infectious complications after transrectal ultrasound‐guided prostate biopsy.
Ahmet Yıldırım Balık +5 more
wiley +1 more source
Defense Systems and Prophage Detection in Streptococcus mutans Strains
Molecular Oral Microbiology, Volume 41, Issue 2, Page 57-68, April 2026.ABSTRACT Although the species is extensively studied, limited data are available on antiphage defense systems (APDSs) in Streptococcus mutans. The present study aimed to explore the diversity and the occurrence of APDSs and to search for prophages in the genomes of clinical isolates of S. mutans using bioinformatics tools.
Olivier Claisse +3 more
wiley +1 more source
Arylhydrazines: Convenient Homogeneous Reductants for Scalable Cross‐Coupling
Angewandte Chemie, Volume 138, Issue 12, 16 March 2026.Reductive cross‐couplings enable efficient C–C bond formation but are limited by the heterogeneity of Zn or costly reagents like TDAE. We report arylhydrazines as inexpensive, convenient reductants for Ni‐catalyzed sp2–sp3 coupling of aryl halides and secondary alkyl iodides. Mechanistic studies support hydrazine‐mediated NiII reduction for a NiI/NiIII
Nils Kurig +5 more
wiley +2 more sources
Gait analysis for functional evaluation in a surgical hindlimb suspension model of muscle atrophy
The Journal of Physiology, Volume 604, Issue 7, Page 2867-2897, 1 April 2026.Abstract figure legend Gait analysis reveals neuromuscular dysfunction following hindlimb suspension and partial recovery after reloading. Schematic overview of the experimental design and principal findings. Mice underwent 14 days of hindlimb suspension (HLS), resulting in muscle atrophy marked by reduced fiber size, satellite cell loss, and decreased
Yanping Xu +13 more
wiley +1 more source
Recurrent Diarrhea Due to Cystoisospora belli in a Patient With HIV: A Case Report. [PDF]
CureusGaxiola Ortiz AV +2 more
europepmc +1 more source
Thermomechanical pressing and immediate quenching: enhanced piezoelectricity and transparency in piezoelectric nanofibers. [PDF]
Nat CommunQu Z +11 more
europepmc +1 more source
Integrating Irreversible Thermodynamics and Response Surface Methodology to Elucidate Nitrate Transport in Nanofiltration and Reverse Osmosis Membranes. [PDF]
Membranes (Basel)Zeggar H +3 more
europepmc +1 more source