Results 231 to 240 of about 41,790 (304)

Design, synthesis, antimicrobial and antioxidant evaluation, cytotoxicity assessment, and molecular dynamics-based computational studies of novel PABA analogues as dual DHPS/DHFR inhibitors. [PDF]

RSC Adv
Devliya B, Al-Kubeisi AK, Patel D, Dabhi M, Patel B, Thakar M, Nagapara J, Chauhan S, Rajput K, Goswami D, Dixit N, Patel SK, Sindhav G, Beshay BY, Patel HD.   +14 more
europepmc   +1 more source

Influence of Subcellular Localization on the Cytotoxicity of Targeted α-Therapy. [PDF]

J Nucl Med
Lee H, Sarkar S, Xu K, Martorano P, Pham J, Park PSU, King AP, Lee HS, Mankoff DA, Pryma DA, Sellmyer MA.   +10 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, Volume 16, Issue 8, Page 1563-1592, August 2026.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Data-Driven Operational Bounds of Transmembrane Pressure for Modelling and Digital Twin Development in Haemodialysis and Haemodiafiltration. [PDF]

Bioengineering (Basel)
Dinu A, Frunzete M, Mihailovschi D.
europepmc   +1 more source

Backbone‐Length‐Optimized Inhibitors Deliver Long‐Retention Selectivity in Area‐Selective ALD of VO2

Advanced Science, Volume 13, Issue 45, 13 August 2026.
Area‐selective VO2 ALD is found to depend critically on inhibitor backbone length, which governs physisorption, chemisorption stability, and packing efficiency in a coupled manner. An intermediate backbone‐length achieves the best long‐retention selectivity, establishing a chemically and geometrically grounded design principle for small‐molecule ...
Hae Lin Yang, Eun Chong Cho, Minchan Kim, Hye In Park, Ga‐young Lee, Seunghwan Lee, Beomseok Kim, Changhwa Jung, Youngkwon Kim, Jin‐Seong Park   +9 more
wiley   +1 more source

Therapeutic effects of Tetramethylpyrazine on Cartilage in Rat Model of Post-traumatic Osteoarthritis. [PDF]

Regen Ther
Duan Z, Gao H, Li P, Tang S, He B.
europepmc   +1 more source

New craniodental materials of Falcarius utahensis (Theropoda: Therizinosauria) reveal patterns of intraspecific variation and cranial evolution in early coelurosaurians

The Anatomical Record, Volume 309, Issue 8, Page 1995-2048, August 2026.
Abstract Despite documented ecomorphological shifts toward an herbivorous diet in several coelurosaurian lineages, the evolutionary tempo and mode of these changes remain poorly understood, hampered by sparse cranial materials for early representatives of major clades. This is particularly true for Therizinosauria, with representative crania best known
William J. Freimuth, Lindsay E. Zanno
wiley   +1 more source

Pneumonia caused by co-infection with Mycobacterium tuberculosis and Pneumocystis jirovecii leading to acute respiratory distress syndrome in an HIV-negative immunocompromised patient: a case report and literature review. [PDF]

BMC Infect Dis
Pan J, Kong H, Liang M, Fang X.
europepmc   +1 more source

Pills and ills: adverse events associated with oral antibiotics for prolonged durations of COpAT treatment courses. [PDF]

Antimicrob Steward Healthc Epidemiol
Siddique N, Benefield RJ, Cummins H, Certain LK.   +3 more
europepmc   +1 more source

Enhancing the Physicochemical Properties of Trimethoprim through Complexation with Sulfathiazole. [PDF]

ACS Omega
Inoue M, Ito M, Utsumi Y, Ye L, Yamashita T, Furuishi T, Fukuzawa K, Yonemochi E.   +7 more
europepmc   +1 more source