Results 121 to 130 of about 33,857 (224)

ACE2 & TMPRSS2 Expressions in Head & Neck Tissues: A Systematic Review

, 2020
International audienceTo review the data regarding the expression of angiotensin converting enzyme-2 (ACE2) and transmembrane protease serine-2 (TMPRSS2) in head and neck tissue.
Barillari, Maria, R, Michel, Justin, Barillari, Maria R, Hsieh, Julien, Saussez, Sven, Hans, Stéphane, Gengler, Isabelle, Chiesa-Estomba, Carlos M, de Riu, Giacomo, Calvo-Henriquez, Christian, Radulesco, Thomas, Cammaroto, Giovanni, Vaira, Luigi, Lechien, Jerome R, Descamps, Géraldine, Chiesa-Estomba, Carlos Miguel, Lechien, Jérôme, Chiesa-Estomba, Carlos,, Sowerby, Leigh, Lechien, Jerome,, Barillari, Maria,, Lechien, Jerome, R, Chiesa-Estomba, Carlos, M, Barillari, Maria Rosaria, Sowerby L., Hsieh J., Michel J., Lechien J. R., Lechien, Jerome R., Descamps G., Barillari, Maria R., Chiesa-Estomba C. M., Saussez S., Radulesco T., Barillari M. R., Cammaroto G., Gengler I., Hans S., Vaira L., Chiesa-Estomba, Carlos M., Calvo-Henriquez C., De Riu G.   +41 more
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Diversity of TMPRSS2-ERG fusion transcripts in the human prostate.

, 2007
TMPRSS2-ERG gene fusions have recently been reported to be present in a high proportion of human prostate cancers. In the current study, we show that great diversity exists in the precise structure of TMPRSS2-ERG hybrid transcripts found in human ...
Phillips, D. H., Eeles, R., Jhavar, S., Kovacs, G., Clark, J., Edwards, S., Martin, Frank L., Fisher, C., Merson, S., Foster, C. S., Crundwell, M., Cooper, C. S., Christmas, T., Flohr, P., Thompson, A.   +14 more
core   +2 more sources

Molecular basis of TMPRSS2 recognition by Paeniclostridium sordellii hemorrhagic toxin

Hemorrhagic toxin (TcsH) is a major virulence factor produced by Paeniclostridium sordellii, which is a non-negligible threat to women undergoing childbirth or abortions.
Yanyan Li, Liang Tao, Liuqing He, Xiechao Zhan, Ruoyu Zhou, Xiaofeng Zhang, Jiahao Zhang   +6 more
core   +1 more source

TMPRSS2: Potential Biomarker for COVID‐19 Outcomes [PDF]

The Journal of Clinical Pharmacology, 2020
Strope, Jonathan D., PharmD, Cindy H. Chau,, Figg, William D.   +2 more
openaire   +2 more sources

Tissue Map Detailing Pathology Determined Benign and Tumor Areas of a Prostatectomy and the Detection of TMPRSS2:ERG mRNA.

, 2016
Representative cartoon showing the selection of benign (blue) and cancer (pink) regions from a radical prostatectomy. The tumor and benign regions were examined for TMPRSS2:ERG mRNA expression (Red ‘+’ indicates positive TMPRSS2:ERG expression, Blue ...
Michael Lipsky (2657503), Mitchell C. Benson (2657512), Wayne D. Comper (745079), Guillermo Salazar (370173), James Lin (819307), Michael J. Donovan (2657506), Leileata M. Russo (562362), Piruz Motamedinia (2657524), Anna N. Scott (2657509), Jennifer Ahn (2657518), Greg W. Hruby (2657521), Neda Sadeghi (2657500), James M. McKiernan (2657494), Kendall L. Bate (2657515), Ketan K. Badani (2657497), Edan Shapiro (2657488), Daniel P. Petrylak (2657491)   +16 more
core   +1 more source

TMPRSS2/ERG Fusions [PDF]

, 2008
Jianghua Wang, Yi Cai, Michael Ittmann
openaire   +1 more source

Expression of ACE2 and TMPRSS2 and the severity of COVID‑19

Biomedical Reports
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for coronavirus disease 2019 (COVID-19), uses the angiotensin-converting enzyme 2 (ACE2) receptor and transmembrane serine protease 2 (TMPRSS2) to enter host cells. Variability in gene expression of these entry factors has been hypothesized to influence susceptibility ...
Sanches De Carvalho, Samantha, Blanco Capassi Santos, Anna Carolina, Shiroma Graziano, Marcos Yuji, Peres, Marina Cristina, Sousa Silva, Renan, Trufelli, Isabella Dudjak Rosa, Luciano Da Veiga, Glaucia, Fonseca, Fernando Luiz Affonso, Da Costa Aguiar Alves, Beatriz   +8 more
openaire   +2 more sources

Pigs lacking TMPRSS2 displayed fewer lung lesions and reduced inflammatory response when infected with influenza A virus

Frontiers in Genome Editing
Influenza A virus (IAV) infection is initiated by hemagglutinin (HA), a glycoprotein exposed on the virion’s lipid envelope that undergoes cleavage by host cell proteases to ensure membrane fusion, entry into the host cells, and completion of the viral ...
Giovana Ciacci Zanella, Giovana Ciacci Zanella, Celeste A. Snyder, Bailey L. Arruda, Kristin Whitworth, Kristin Whitworth, Erin Green, Ravikanth Reddy Poonooru, Bhanu P. Telugu, Bhanu P. Telugu, Amy L. Baker   +10 more
doaj   +1 more source

TMPRSS2 wt Allele [PDF]

, 2020
openaire   +1 more source

Monoclonal antibodies against human TMPRSS2 prevent infection by any SARS-CoV-2 variant

Summary: The transmembrane serine protease 2 (TMPRSS2) plays a critical role in SARS-CoV-2 infection by priming the viral Spike (S) protein for host cell entry and thus represents a potential target for COVID-19 therapy. Here monoclonal antibodies (mAbs)
Jin Goda, Tamao Hisano, Takehisa Matsumoto, Yasushi Kawaguchi, Mariko Ikeda, Yoshiko Ishizuka-Katsura, Haruhiko Koseki, Natsumi Yoneda, Yoshinobu Hashizume, Jun-ichiro Inoue, Kenichi Ohtaki, Minoru Yoshida, Natsuki Kojima, Kazuharu Hanada, Mikako Shirouzu, Cong Thanh Nguyen, Rina Hashimoto, Makoto Takeda, Akiko Sugimoto-Ishige, Hirohito Ishigaki, Manabu Nakayama, Masashi Matsuda, Yasushi Itoh, Misako Nakayama, Machie Sakuma, Mizuki Yamamoto, Takako Yamamoto, Toshiaki Hosaka, Kazuo Takayama, Michishige Harada, Akiko Idei, Toshie Kaizuka, Kosuke Miyauchi, Takashi Saito, Kazushige Katsura   +34 more
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