Results 131 to 140 of about 31,828 (224)

Reply to “Preclinical and Clinical Evidence on Chloroquine or Hydroxychloroquine in COVID‐19”: Achieving Statistical Significance Does Not Mean That Clinical Relevance Can Be Disregarded, and This Must Be Considered When Interpreting Results

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
Inès Ben Ghezala, Marc Bardou
wiley   +1 more source

TMPRSS2: Potential Biomarker for COVID‐19 Outcomes [PDF]

The Journal of Clinical Pharmacology, 2020
Strope, Jonathan D., PharmD, Cindy H. Chau,, Figg, William D.   +2 more
openaire   +2 more sources

Expression of TMPRSS2 isoforms 1 and 2.

, 2015
(A) Sequence alignment of the N-termini of TMPRSS2 isoforms 1 and 2. Identical amino acids are marked with stars. Amino acids absent in isoform 2 are marked with ‘–‘. (B) Plasmids encoding TMPRSS2 isoform 1 and isoform 2, both equipped with an N-terminal
Anna-Sophie Moldenhauer (142435), Heike Hofmann-Winkler (797086), Stefan Pöhlmann (142445), Pawel Zmora (797085)   +3 more
core   +1 more source

TMPRSS2/ERG Fusions [PDF]

, 2008
Jianghua Wang, Yi Cai, Michael Ittmann
openaire   +1 more source

Pigs lacking TMPRSS2 displayed fewer lung lesions and reduced inflammatory response when infected with influenza A virus

Frontiers in Genome Editing
Influenza A virus (IAV) infection is initiated by hemagglutinin (HA), a glycoprotein exposed on the virion’s lipid envelope that undergoes cleavage by host cell proteases to ensure membrane fusion, entry into the host cells, and completion of the viral ...
Giovana Ciacci Zanella, Giovana Ciacci Zanella, Celeste A. Snyder, Bailey L. Arruda, Kristin Whitworth, Kristin Whitworth, Erin Green, Ravikanth Reddy Poonooru, Bhanu P. Telugu, Bhanu P. Telugu, Amy L. Baker   +10 more
doaj   +1 more source

Szelektív TMPRSS2 gátlószer in vitro farmakológiai jellemzése

, 2015
A TMPRSS2 egy olyan membránhoz kötött szerin proteáz enzim, amely szerepet játszik az influenzavírusos megbetegedésekben és egyes daganatok esetén a metasztázis képződés folyamatában. Célunk egy szintetikus 3-amidinofenilalanin alapvázú szelektív TMPRSS2
Czimmermann, Ágnes Eszter
core  

TMPRSS2: A Key Host Factor in SARS-CoV-2 Infection and Potential Therapeutic Target

Medeniyet Medical Journal
The transmembrane serine protease 2 (TMPRSS2) gene plays a crucial role in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection by priming the viral spike protein for membrane fusion and facilitating viral entry into host cells.
Haily Liduin KOYOU, Mohd Nazil SALLEH, Caroline Satu JELEMIE, Mohd Jaamia Qaadir BADRIN, Muhammad Evy PRASTIYANTO, Vasudevan RAMACHANDRAN   +5 more
doaj   +1 more source

TMPRSS2 wt Allele [PDF]

, 2020
openaire   +1 more source

TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the SARS-coronavirus spike-protein

, 2014
The type II transmembrane serine proteases TMPRSS2 and HAT can cleave and activate the spike protein (S) of the severe acute respiratory syndrome coronavirus (SARS-CoV) for membrane fusion.
Heurich, A., Liepold, T., Liepold, Thomas, Hofmann-Winkler, Heike, Hofmann-Winkler, H., Gierer, S., Heurich, Adeline, Gierer, Stefanie, Pöhlmann, S., Jahn, Olaf, Jahn, O., Pöhlmann, Stefan   +11 more
core   +1 more source

Human Transmembrane Serine Protease 2 (TMPRSS2) on Human Seminal Fluid Extracellular Vesicles Is Proteolytically Active

Journal of Extracellular Vesicles
Human transmembrane serine protease 2 (TMPRSS2) has garnered substantial interest due to its clinical significance in various pathologies, notably its pivotal role in viral entry into host cells.
Emile Verhulst, Michelle De Bruyn, Pascale Berckmans, Yani Sim, Koen Augustyns, Isabel Pintelon, Maya Berg, Pieter Van Wielendaele, Anne‐Marie Lambeir, Yann G.‐J. Sterckx, Inge Nelissen, Ingrid De Meester   +11 more
doaj   +1 more source