Results 111 to 120 of about 33,857 (224)

Influenza pseudotype production with TMPRSS2

, 2013
The human Transmembrane Protease Serine 2 is necessary for the produc5on of Group 2 influenza A virus pseudotypes. This poster was presented at the Spring meeting of the SGM, Manchester 2013.
openaire   +1 more source

Systematic analysis of genomic alterations in prostate cancer [PDF]

, 2011
PhDProstate cancer is the most common male cancer in Western countries. The genetic mechanism underlying its initiation and progression is still unclear.
Mao, Xueying
core   +1 more source

Preclinical Evaluation of Bacterial Lysates in Murine Disease Models: A Systematic Review

Immunity, Inflammation and Disease, Volume 14, Issue 10, October 2026.
ABSTRACT Background Bacterial lysates are biologically active preparations obtained by thermal, mechanical, or chemical inactivation of whole bacterial cells, preserving their immunomodulatory properties. Methods This systematic review evaluates preclinical studies published between 2010 and 2025 that investigated bacterial lysates in murine disease ...
Diana‐Larisa Ancuța, Cristin Coman
wiley   +1 more source

CRISPR-Cas9 genetic screens reveal regulation of TMPRSS2 by the Elongin BC-VHL complex

Scientific Reports
The TMPRSS2 cell surface protease is used by a broad range of respiratory viruses to facilitate entry into target cells. Together with ACE2, TMPRSS2 represents a key factor for SARS-CoV-2 infection, as TMPRSS2 mediates cleavage of viral spike protein ...
Ildar Gabaev, Alexandra Rowland, Emilija Jovanovic, Christian M. Gawden-Bone, Thomas W. M. Crozier, Ana Teixeira-Silva, Edward J. D. Greenwood, Pehuén Pereyra Gerber, Niek Wit, James A. Nathan, Nicholas J. Matheson, Paul J. Lehner   +11 more
doaj   +1 more source

Association of IFN‐γ +874 T/A Polymorphism With COVID‐19 Susceptibility, Severity, and Inflammatory Response: A Case–Control Study From Southern Iran

Journal of Clinical Laboratory Analysis, Volume 40, Issue 20, October 2026.
Graphical abstract illustrating the association between IFN‐γ +874 T/A polymorphism and COVID‐19 outcomes. TA and AA genotypes are linked to increased susceptibility, higher inflammatory markers (notably IL‐6), greater disease severity, and longer hospitalization.
Nasir Arefinia, Bahman Aghcheli, Seyed Mohammad Ali Hashemi, Zohreh‐al‐sadat Ghoreshi, Emad Behboudi   +4 more
wiley   +1 more source

The membrane-anchored serine protease, TMPRSS2, activates PAR-2 in prostate cancer cells.

, 2005
TMPRSS2 is a type II transmembrane-bound serine protease that has gained interest owing to its highly localized expression in the prostate and its overexpression in neoplastic prostate epithelium.
Hawthorne, Susan, Zijlstra, A, Zijlstra, Andries, Hawthorne, Susan J., Hawthorne, S, Hooper, J., Wilson, Susan K., Quigley, J, Wilson, S, Greer, B, Walker, Brian, Zijlstra, A., Quigley, J.P., Quigley, James, Hooper, John D., Hooper, J, Walker, B, Wilson, S., Greer, Brett   +18 more
core   +1 more source

Longitudinally Monitoring Prostate Cancer Bone Metastasis and Treatment Response via Circulating Extracellular Vesicles

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
ABSTRACT Lethal prostate cancer (PCa) is dominated by treatment‐refractory progression in bone. In this study, we used plasma‐derived extracellular vesicles (EVs) for monitoring the tumour and therapy‐induced changes in the bone tumour microenvironment (bone‐TME) in men with bone metastatic PCa (M1b PCa).
Emanuela Gentile, Paul G. Corn, Martha Zavridou, James P. Long, Jian H. Song, Anh Hoang, Andrew W. Hahn, Eleonora Dondossola, William Norton, Sue‐Hwa Lin, Christopher J. Logothetis, Theocharis Panaretakis   +11 more
wiley   +1 more source

Genome‐Wide Association Studies of Hospitalized Influenza Identify Four Risk Loci and Reveal Shared and Unique Genetic Factors Compared With COVID‐19

Influenza and Other Respiratory Viruses, Volume 20, Issue 10, October 2026.
ABSTRACT Background Influenza remains a significant global health burden, potentially leading to hospitalization and mortality. Although previous studies have explored genetic susceptibility to influenza infection, the genetic basis of influenza hospitalization and its relationship with respiratory diseases like COVID‐19 remain poorly understood ...
Xiao Xue, Yaning Feng, Yu‐Ping Lin, Pui‐Ching Chan, Hon‐Cheong So   +4 more
wiley   +1 more source

Status of TMPRSS2–ERG fusion in prostate cancer patients from India: correlation with clinico-pathological details and TMPRSS2 Met160Val polymorphism

, 2018
Background: Prostate cancer (PCa) shows considerable clinical heterogeneity that has been primarily attributed to variable molecular alterations. TMPRSS2–ERG fusion is one such molecular subtype that has been associated with predominantly poor prognosis.
Aparna Bhanushali, Vaishnavi Raman, Asawari Ambekar, Prajakta Kokate, Swarna Mandva, Pranesh Rao, Simi Bhatia, B.R. Das   +7 more
core   +1 more source

Alignment analysis of TMPRSS2 protein tertiary structure.

Alignment analysis of TMPRSS2 protein tertiary structure.
Marzieh Eskandarzadeh (18388767), Ali Mohebbi (4433587), Hanieh Zangi (18388770), Marzie Fatehi (18388773)   +3 more
core   +1 more source