Results 91 to 100 of about 33,857 (224)
The Prostate, EarlyView.ABSTRACT Background For prostate cancer (PCa), early diagnosis and biomarker‐based patient stratification can improve clinical decision‐making and post‐treatment prognosis. PCa biomarkers are best validated in tissue following comprehensive histopathologic review; however, urinary biomarkers can be obtained non‐invasively and are therefore safer and ...
Yuandong Xing +11 more
wiley +1 more source
Binding free energies calculation of TMPRSS2-L3, TMPRSS2-L6, and TMPRSS2-L7.
Binding free energies calculation of TMPRSS2-L3, TMPRSS2-L6, and TMPRSS2-L7.
Marzieh Eskandarzadeh (18388767) +3 more
core +1 more source
DataSheet1_Virtual Screening on Marine Natural Products for Discovering TMPRSS2 Inhibitors.zip
, 2021 Although SARS-CoV-2 entry to cells strictly depends on angiotensin-converting enzyme 2 (ACE2), the virus also needs transmembrane serine protease 2 (TMPRSS2) for its spike protein priming.
Maryam Farrokhnia (1668937) +3 more
core +1 more source
Urinary Soluble Collagen Levels Are Associated With Moderate/Severe LUTS
The Prostate, EarlyView.ABSTRACT Background Expansion of the stromal compartment of the prostate concurrent with fibroblast activation and increased collagenization is now recognized as a pathobiology likely contributing to Lower Urinary Tract Symptoms (LUTS). However, approaches to quantitatively and, ideally, non‐invasively, assess prostatic collagenization in vivo are not ...
Marissa Sarna‐McCarthy +5 more
wiley +1 more source
Addressing Sex and Gender Bias in COVID-19 Epidemiology in Bangladesh
Journal of Agriculture, Food and Environment, 2021 Sex and gender are recognized as a vital factor in the infectious disease epidemiology,and disease outcomes,and these two factors also appear to hold for severe acute respiratory syndrome (SARS-CoV-2)infection.
M. A. Islam
doaj +1 more source
Cytology‐First Diagnostic Workflow for Melanoma of Unknown Primary With Molecular Profiling
Cytopathology, EarlyView.Cytology‑first diagnostic workflow for melanoma of unknown primary. Fine‑needle aspiration of an enlarged lymph node enables rapid cytologic evaluation and immunocytochemical confirmation of melanocytic lineage (SOX10). This early cytologic diagnosis facilitates timely surgical excision and comprehensive genomic profiling, supporting integrated ...
Hong Yu +3 more
wiley +1 more source
Spontaneous Binding of Potential COVID-19 Drugs to Human Serine Protease TMPRSS2 [PDF]
, 2020 Effective treatment or vaccine is not yet available for combating SARS coronavirus 2 (SARSCoV-2) that caused the COVID-19 pandemic. Recent studies showed that two drugs, Camostat and Nafamostat, might be repurposed to treat COVID-19 by inhibiting human ...
Haixia, Zhu +5 more
core +1 more source
Diabetic Medicine, EarlyView.Abstract Aims Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is more severe in people with diabetes mellitus due to immune dysfunction, exacerbated inflammation and increased risk of co‐morbidities and mortality.
Taís Mendes Camargo +4 more
wiley +1 more source
ACE2 and TMPRSS2 Immunolocalization and COVID-19-Related Thyroid Disorder
, 2022 SIMPLE SUMMARY: We analyzed the underlying mechanism of thyroidal manifestations in patients with COVID-19 using ACE2 and TMPRSS2 immunostaining. Prior to our work, few studies had investigated the mRNA expression of ACE2 in the thyroid gland.
Han, Ji-Min +23 more
core +1 more source
H2 influenza A virus is not pathogenic in Tmprss2 knock-out mice
Virology Journal, 2020 The host cell protease TMPRSS2 cleaves the influenza A virus (IAV) hemagglutinin (HA). Several reports have described resistance of Tmprss2 −/− knock-out (KO) mice to IAV infection but IAV of the H2 subtype have not been examined yet.
Ruth Lydia Olga Lambertz +8 more
doaj +1 more source