Results 71 to 80 of about 31,828 (224)
, 2016 (A) Genomic structure of the TMPRSS2–ERG fusion transcripts discovered from deep sequencing data by InFusion. Isoform 3 is a known transcript, while isoforms 1 and 2 are novel. Transcript names are taken from the Ensembl v.68 database.
Alexander Seitz (3372767) +5 more
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DataSheet1_Virtual Screening on Marine Natural Products for Discovering TMPRSS2 Inhibitors.zip
, 2021 Although SARS-CoV-2 entry to cells strictly depends on angiotensin-converting enzyme 2 (ACE2), the virus also needs transmembrane serine protease 2 (TMPRSS2) for its spike protein priming.
Maryam Farrokhnia (1668937) +3 more
core +1 more source
TMPRSS2 gene polymorphism common in East Asians confers decreased COVID-19 susceptibility
Frontiers in Microbiology, 2022 COVID-19 has a wide range of clinical presentations, and the susceptibility to SARS-CoV-2 infection and the mortality rate also vary by region and ethnicity.
Takeshi Sekiya +20 more
doaj +1 more source
Spontaneous Binding of Potential COVID-19 Drugs to Human Serine Protease TMPRSS2
, 2020 Effective treatment or vaccine is not yet available for combating SARS coronavirus 2 (SARSCoV-2) that caused the COVID-19 pandemic. Recent studies showed that two drugs, Camostat and Nafamostat, might be repurposed to treat COVID-19 by inhibiting human ...
Haixia, Zhu +5 more
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Paramyxoviruses activation by host proteases in cultures of normal and cancer cells
Вопросы вирусологии, 2017 Multiplication of paramyxovirus Sendai and Newcastle disease virus (NDV) was studied in cultures of normal and tumor cells. Production of noninfectious virus with uncleaved F0 was observed in canine kidney cell line MDCK (line H) and its derivatives ...
O. P. Zhirnov
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
ACE2 and TMPRSS2 Immunolocalization and COVID-19-Related Thyroid Disorder
, 2022 SIMPLE SUMMARY: We analyzed the underlying mechanism of thyroidal manifestations in patients with COVID-19 using ACE2 and TMPRSS2 immunostaining. Prior to our work, few studies had investigated the mRNA expression of ACE2 in the thyroid gland.
Han, Ji-Min +23 more
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The association of ACE1, ACE2, TMPRSS2, IFITM3 and VDR polymorphisms with COVID-19 severity
EXCLI Journal : Experimental and Clinical Sciences, 2022 Genes involved in the regulation of viral recognition and its entry into a host cell have been identified as candidates for genetic association studies on COVID-19 severity.
Zorana Dobrijević +6 more
doaj +1 more source
Advanced Science, EarlyView.This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu +18 more
wiley +1 more source
PCA3 and TMPRSS2: ERG Urine Level as Diagnostic Biomarker of Prostate Cancer
, 2023 Syah Mirsya Warli,1,2 Muhammad Haritsyah Warli,3 Fauriski Febrian Prapiska2 1Department of Urology, Faculty of Medicine Universitas Sumatera Utara – Universitas Sumatera Utara Hospital, Medan, North Sumatera, Indonesia; 2Department of Surgery Urology ...
Prapiska FF, Warli SM, Warli MH
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