Results 101 to 110 of about 31,965 (231)

TMPRSS2:ETS gene fusions in prostate cancer [PDF]

, 2011
Deep insight on TMPRSS2:ETS gene fusions in prostate ...
Yoshimoto, M, Squire, JA, Boag, AH, Park, PC, Williams, JL   +4 more
core   +1 more source

Viruses, Periodontitis, and Systemic Diseases

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the viral involvement in periodontitis and its relevance for systemic diseases. The oral cavity acts as an active viral reservoir and dissemination platform, where virus–microbiome interactions may promote dysbiosis, periodontitis progression, and systemic inflammatory effects, while the ...
Kim Natalie Solte, Yvonne L. Hernandez‐Kapila, Henrik Dommisch   +2 more
wiley   +1 more source

Prostate cancer risk regions at 8q24 and 17q24 are differentially associated with somatic TMPRSS2:ERG fusion status [PDF]

, 2016
Molecular and epidemiological differences have been described between TMPRSS2:ERG fusion-positive and fusion-negative prostate cancer (PrCa). Assuming two molecularly distinct subtypes, we have examined 27 common PrCa risk variants, previously identified
Geybels, Milan S., PRACTICAL consortium,, Stanford, Janet L, Wach, Sven, Teixeira, Manuel R, Cannon-Albright, Lisa, Kuefer, Rainer, Perner, S, Teixeira, MR, Teixeira, Manuel R., Krause, H, Al Olama, AA, Geybels, MS, Tammela, TLJ, Benlloch, Sara, Ostrander, Elaine A, Krause, Hans, Parker, C, Cooper, Colin S, Goh, CL, Jerónimo, C, Schleutker, Johanna, Rau, TT, Geybels, Milan S, Benlloch, S, Fitzgerald, Liesel M., Hofer, Matthias D, Henrique, R, Stanford, JL, Jerónimo, Carmen, Visakorpi, Tapio, Hofer, MD, Hofer, Matthias D., Weikert, S, Cooper, CS, Henrique, Rui, Lieb, Verena, Cannon-Albright, L, Wach, S, FitzGerald, Liesel M, Ostrander, Elaine A., Kuefer, R, Herkommer, K, Easton, Doug F, Visakorpi, T, Flohr, P, FitzGerald, LM, Schleutker, J, Rinckleb, AE, Lieb, V, Vogel, Walther, Goh, Chee L, Eeles, Rosalind A, Hoegel, Josef, Leinonen, Katri A, Easton, DF, Parker, Chris, Cooper, Colin S., Ostrander, EA, Herkommer, Kathleen, Rubin, Mark A., Kote-Jarai, Zsofia, Rau, Tilman T., Maier, C, Rubin, MA, Goh, Chee L., Tammela, Teuvo L J, Vogel, W, Paulo, P, Kote-Jarai, Z, Leinonen, KA, Amin Al Olama, Ali, Maier, Christiane, Flohr, Penny, Easton, Doug F., Luedeke, Manuel, Wahlfors, Tiina, Rubin, Mark A, Edwards, Sandra, McCarthy, F, Luedeke, M, Agarwal, AM, Weikert, Steffen, Eeles, RA, Wahlfors, T, Rau, Tilman, Rinckleb, Antje E, Agarwal, Archana M, Tammela, Teuvo L. J., Hoegel, J, Leinonen, Katri A., Paulo, Paula, McCarthy, Frank, Perner, Sven, Edwards, S, Rinckleb, Antje E., Agarwal, Archana M., Eeles, Rosalind A.   +97 more
core   +1 more source

Addressing Sex and Gender Bias in COVID-19 Epidemiology in Bangladesh

Journal of Agriculture, Food and Environment, 2021
Sex and gender are recognized as a vital factor in the infectious disease epidemiology,and disease outcomes,and these two factors also appear to hold for severe acute respiratory syndrome (SARS-CoV-2)infection.
M. A. Islam
doaj   +1 more source

H2 influenza A virus is not pathogenic in Tmprss2 knock-out mice

Virology Journal, 2020
The host cell protease TMPRSS2 cleaves the influenza A virus (IAV) hemagglutinin (HA). Several reports have described resistance of Tmprss2 −/− knock-out (KO) mice to IAV infection but IAV of the H2 subtype have not been examined yet.
Ruth Lydia Olga Lambertz, Ingo Gerhauser, Inga Nehlmeier, Sabine Gärtner, Michael Winkler, Sarah Rebecca Leist, Heike Kollmus, Stefan Pöhlmann, Klaus Schughart   +8 more
doaj   +1 more source

SARS‐CoV‐2 targets mitochondria, exacerbating COVID‐19 pneumonia

The Journal of Physiology, EarlyView.
Abstract figure legend Following entry into airway epithelial cells (AECs), SARS‐CoV‐2 releases its single‐stranded RNA into the cytoplasm, where it is translated into viral proteins. Several of these viral proteins localize to mitochondria and interact with key mitochondrial components.
Danchen Wu, Asish Dasgupta, Jaskaran Singh Hora, Kuang‐Hueih Chen, Arinjay Banerjee, Stephen L. Archer   +5 more
wiley   +1 more source

Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure

Journal of Applied Toxicology, Volume 46, Issue 9, Page 3274-3287, September 2026.
ABSTRACT The tumor microenvironment (TME) influences prostate cancer (PCa) progression through stromal and immune interactions. Adipose‐derived mesenchymal stromal cells (ASCs) modulate immune tone, while inorganic arsenic (iAs), a widespread toxicant, is linked to immune suppression and carcinogenesis.
Joseph J. Shearer, Cosette Rivera‐Cruz, Alexandre M. B. Cavalca, Carlos Eduardo Fonseca‐Alves, Marxa L. Figueiredo   +4 more
wiley   +1 more source

TMPRSS2-ERG fusion promotes prostate cancer metastases in bone. [PDF]

, 2017
Bone metastasis is the major deleterious event in prostate cancer (PCa). TMPRSS2-ERG fusion is one of the most common chromosomic rearrangements in PCa. However, its implication in bone metastasis development is still unclear.
Marchand, Nathalie, Deplus, Rachel, Delliaux, Carine, Duterque-Coquillaud, Martine, De Launoit, Yvan, Leroy, Xavier, Vanpouille, Nathalie, Flourens, Anne   +7 more
core   +3 more sources

Prostate Cancer Development, Progression, and Therapy

MedComm – Oncology, Volume 5, Issue 3, September 2026.
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin, Zicheng Xiao, Zexian Ding, Wei Li, Ruijiang Zeng, Yujun Shuai, Weimin Ci, Dan Xia, Xu Zhang, Haojie Huang   +9 more
wiley   +1 more source

Charakterisierung der hämagglutininspaltenden Transmembranserinproteasen Matriptase und TMPRSS2 [PDF]

, 2020
Influenza is one of the commonest infectious diseases affecting millions of people every year including 290,000 – 650,000 heavy casualties. Influenza viruses undergo constant genetic changes and every 10 – 50 years new influenza virus strains emerge that
Keils, Aline
core   +1 more source