Results 101 to 110 of about 33,857 (224)
Unmasking the Influence of Viral Micro‐RNAs on Host Immunity
Immunology &Cell Biology, EarlyView.Viral micro‐RNAs are increasingly recognized as key modulators of host–virus interactions. They influence multiple immune functions, including antigen presentation, T‐cell activation, and cytokine signaling, while also tuning viral gene expression to promote persistence.
Riley J. K. Easton +1 more
wiley +1 more source
SARS-CoV-2 infection releated to ACE2 and TMPRSS2 protein distribution at 4-dpi, related to Fig 5.
, 2022 TMPRSS2 imaged in the 555 channel, NP in the 647 channel and ACE2 in the 730 channel. Merges of all channels shown in red (ACE2), green (NP) and blue (TMPRSS2). (A/B) ACE2 and TMPRSS2 signal in the nasal cavity with SARS-CoV-2 infection overlap.
Kim M. Bouwman (4112605) +13 more
core +1 more source
Viruses, Periodontitis, and Systemic Diseases
Journal of Periodontal Research, EarlyView.This narrative review aimed to summarize current evidence on the viral involvement in periodontitis and its relevance for systemic diseases. The oral cavity acts as an active viral reservoir and dissemination platform, where virus–microbiome interactions may promote dysbiosis, periodontitis progression, and systemic inflammatory effects, while the ...
Kim Natalie Solte +2 more
wiley +1 more source
SARS‐CoV‐2 targets mitochondria, exacerbating COVID‐19 pneumonia
The Journal of Physiology, EarlyView.Abstract figure legend Following entry into airway epithelial cells (AECs), SARS‐CoV‐2 releases its single‐stranded RNA into the cytoplasm, where it is translated into viral proteins. Several of these viral proteins localize to mitochondria and interact with key mitochondrial components.
Danchen Wu +5 more
wiley +1 more source
Human brain matters: Navigating the neuropathology of COVID‐19
Brain Pathology, Volume 36, Issue 6, November 2026.Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland +4 more
wiley +1 more source
Hitting Coronaviruses Where It Hurts: Antiviral Strategies Targeting Viral Proteins
ChemMedChem, Volume 21, Issue 19, 14 October 2026.Viral proteins represent key vulnerabilities in human coronaviruses (HCoVs). This review outlines inhibitors targeting spike (S), main protease (Mpro), papain‐like protease (PLpro), and RNA‐dependent RNA polymerase (RdRp), mapping chemically diverse strategies that disrupt entry and replication, and provides an integrated view of current candidates ...
Álvaro de la Cruz‐Potenciano +3 more
wiley +1 more source
Cancer Reports, Volume 9, Issue 10, October 2026.ABSTRACT Background Prostate cancer (PCa) is the most common solid tumor in American men, with persistent ethnic disparities, particularly among Hispanic American (HA) men. The tumor microenvironment (TME) and tumor genomics may contribute to disease progression but remain undercharacterized in HA populations.
Alejandro Recio‐Boiles +10 more
wiley +1 more source
Increased ACE2 and TMPRSS2 expression in ulcerative colitis
Pathology - Research and PracticeUlcerative colitis (UC) is a cryptogenic inflammatory bowel disease, and there is an urgent need to elucidate its pathogenesis. ACE2 and TMPRSS2, the entry molecules of SARS-CoV-2, are reportedly associated with the disease; however, no consensus has been reached yet.
Yuichiro Hamamoto +7 more
openaire +4 more sources
ARMS PCR primers for TMPRSS2 rs12329760 genotyping.
, 2023 ARMS PCR primers for TMPRSS2 rs12329760 genotyping.
Masoumeh Amini (14636587) +5 more
core +1 more source
Food Safety and Health, Volume 4, Issue 4, Page 762-770, October 2026.This review summarizes the chemical constituents and functional characteristics of American ginseng, aiming to provide references for its development and application. ABSTRACT American ginseng, a perennial herbaceous plant, is recognized for its significant medicinal properties and has attracted considerable attention due to its diverse phytochemical ...
Wei Geng +5 more
wiley +1 more source