Targeting Tn Antigen Suppresses Aberrant O-Glycosylation-Elicited Metastasis in Breast Cancer. [PDF]
J Cell Mol MedDu T +6 more
europepmc +1 more source
Thomsen-Friedenreich antigen (T antigen) has been supposed to be a cancer-specific carbohydrate antigen. We have previously shown that one third of the Japanese population normally expressed T antigen in gastric surface epithelia and the other two thirds
Tsuji, Takao +4 more
core
Polymeric α‐Hairpinin Allergens Induce a Functional Response via a Single Antibody
Allergy, EarlyView.
Gage O. Leighton +16 more
wiley +1 more source
Long‐term oncological outcomes from a prospective cohort of patients with localised prostate cancer
BJU International, EarlyView.Objectives To report long‐term oncological outcomes for men with clinically localised prostate cancer (PCa) treated with contemporary modalities in a population‐based United States cohort. Patients and Methods The Comparative Effectiveness Analysis of Surgery and Radiation (CEASAR) study prospectively enrolled men with clinically localised PCa from ...
Avi S. Baskin +17 more
wiley +1 more source
Stereoselective Multigram-Scale Tn Antigen Synthesis via the Iron-Catalyzed Glycal 1,2-<i>cis</i>-Aminoglycosylation. [PDF]
Org LettYin L, Zhang D, Jiang Z, Xu H.
europepmc +1 more source
Brain Pathology, EarlyView.Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen +8 more
wiley +1 more source
Detection of Tn-antigen in breast and prostate cancer models by VVL-labeled red dye-doped nanoparticles. [PDF]
Nanomedicine (Lond)Verhassel A +6 more
europepmc +1 more source
Globohexaosylceramide (globo-H); ganglioside GM2 (GM2); Thomsen-Friedenreich antigen (TF); Tn antigen (Tn); sialosyl-Tn antigen (sTn) [PDF]
Science-Business eXchange, 2009 openaire +1 more source
Brain Pathology, EarlyView.Brain metastasis‐associated fibroblasts are active stromal components of the metastatic niche characterised by extracellular matrix remodelling and production of pro‐migratory mediators. They promote monocyte and cancer cell migration and enhance cancer cell invasion while having no growth‐promoting effect on cancer cells.
Barbora Výmolová +19 more
wiley +1 more source
Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
British Journal of Pharmacology, EarlyView.This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source