Results 111 to 120 of about 683,828 (283)

Tn antigens and their significance in oncology.

Acta Biochimica Polonica, 1995
Tn and sialyl-Tn carbohydrate structures, first identified in glycophorins of persons with the rare Tn syndrome, were found to be present on the surface of most cancer cells. In this article, the studies on Tn and sialyl-Tn antigens as diagnostic and prognostic tumor markers and as immunogens in vaccines for cancer immunotherapy are shortly reviewed.
openaire   +3 more sources

Dexmedetomidine infusions improve cardiovascular and renal function in anaesthetised, experimentally endotoxaemic horses

Equine Veterinary Journal, EarlyView.
Abstract Background Dexmedetomidine infusions are beneficial in anaesthetised endotoxaemic horses when administered concurrent to endotoxin, but post‐conditioning effects are unknown. Objectives To evaluate whether a dexmedetomidine infusion is beneficial in horses administered Escherichia coli O55:B5 lipopolysaccharides (LPS) endotoxin prior to ...
Sera Lee, Rachel C. Hector, Lynn Pezzanite, Eric Gilleland, Marlis L. Rezende   +4 more
wiley   +1 more source

Towards the Synthesis of a C-glycoside Serine Tn Antigen [PDF]

Sustainable IndustryTowards the Synthesis of a C-glycoside Serine Tn Antigen Thomson Ly, Advait Desai, Iraj Sadraei, John F. Trant Many biological processes including bacterial and viral infections (notably HIV and the flu), immunogenic responses, and ...
Ly, Thomson
core   +4 more sources

Comparison of HPV Antibodies Measured Prior to Diagnosis of Anal, Cervical, Oropharyngeal, Penile and Vaginal Cancers in the HPV Cancer Cohort Consortium

International Journal of Cancer, EarlyView.
ABSTRACT Antibodies against HPV proteins can provide pre‐diagnostic information about cancer development. We described the prevalence of antibodies to proteins of oncogenic HPV types prior to diagnosis of HPV‐related cancers. We analysed pre‐diagnostic blood from 1700 participants with incident HPV‐related cancers (anal = 387, cervical = 274 ...
Justina Ucheojor Onwuka, Marie‐Pierre Nobels, Aimée R. Kreimer, Lea Schroeder, Aida Ferreiro‐Iglesias, Ilir Agalliu, Demetrius Albanes, Qiuyin Cai, Gypsyamber D'Souza, Neal D. Freedman, Graham G. Giles, Allan Hildesheim, Wen‐Yi Huang, Kristian Hveem, Hilde Langseth, Roger L. Milne, Eivind Ness‐Jensen, Nicolas F. Schlecht, Lesley F. Tinker, Giske Ursin, Kala Visvanathan, Sylvia Wassertheil‐Smoller, Stephanie J. Weinstein, Wei Zheng, Mari Nygard, Mattias Johansson, Tim Waterboer, Gary M. Clifford, Hilary A. Robbins   +28 more
wiley   +1 more source

Anti‐NMDA receptor autoimmune encephalitis associated with ovarian teratoma: A case series and literature review

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 23-30, April 2025.
Abstract Autoimmune encephalitis is a group of disorders characterized by symptoms of dysfunction of the limbic and extra‐limbic systems that occur in association with antibodies against intracellular antigens, synapses, or proteins located on the surface of nerve cells. Anti‐NMDA (N‐methyl‐D‐aspartate) receptor encephalitis was first described in 2007
Pham Ba Nha, Nguyen Phuong Tu, Nguyen Viet Ha, Duong Thi Thu Hien, Nguyen Thi Thu Phuong, Nguyen Anh Son, Nguyen Tien Hoang   +6 more
wiley   +1 more source

Simple mucins (T, sialosyl-T, Tn and sialosyl-Tn) are not diagnostic for malignant breast lesions

, 1994
Immunohistochemical study of the distribution of carbohydrate core-structures on O-linked glycoproteins (T, sialosyl-T, Tn and sialosyl-Tn) was performed using specific monoclonal antibodies on 148 primary breast lesions, including 10 normal breast ...
Bryne, M., Bryne, M, Nesland, J.M., Reed, W, Clausen, H, Reed, W., Dabelsteen, Erik, Clausen, Henrik, Nesland, J M   +8 more
core  

CSRP1 Drives Helicobacter pylori‐Associated Gastric Cancer Progression via IL‐6/JAK2/STAT3‐Mediated Epithelial–Mesenchymal Transition

iNew Medicine, EarlyView.
Helicobacter pylori infection‐associated chronic gastritis induces CSRP1 upregulation in gastric cancer cells. Elevated CSRP1 activates the IL‐6/JAK2/STAT3 signaling pathway by promoting IL‐6 expression, JAK2 phosphorylation, and STAT3 nuclear translocation.
Chao Li, Wanjing Chen, Yawei He, Yida Lu, Gang Yu, Ruqiong Wei, Raquel Alarcón Rodríguez, Zhengguang Wang   +7 more
wiley   +1 more source

Immunohistochemical study of Tn, sialosyl-Tn and T antigens in human meningiomas.

European journal of histochemistry : EJH, 1998
Since an aberrant glycosylation associated with abnormal expression of cell surface carbohydrates has been described in many human tumours, we have investigated the expression of simple mucintype carbohydrate antigens (Tn, sialosyl-Tn and T) in 30 formalin-fixed paraffin-embedded surgical specimens of primary meningiomas, subdivided according to the ...
GIUFFRE', Giuseppe, VITARELLI E, TUCCARI, Giovanni, BARRESI, Gaetano   +3 more
openaire   +2 more sources

Standardization of the Monocyte Monolayer Assay: Lessons Learned From Laboratory Optimization and Literature Review

Journal of Clinical Laboratory Analysis, EarlyView.
Standardization of monocyte monolayer assay in a developing country. This study highlights the significance of literature review and adopting best techniques for standardization of a new procedure at individual center before implementing into practice. ABSTRACT Objectives Several variables influence the outcome of cellular assays.
Shamee Shastry, Kavya Babu, Deepika Chenna, Ganesh Mohan, Kartik Iyer   +4 more
wiley   +1 more source

Tn antigen interactions of macrophage galactose-type lectin (MGL) in immune function and disease. [PDF]

Glycobiology, 2023
Tumoglu B, Keelaghan A, Avci FY.
europepmc   +1 more source