Results 171 to 180 of about 683,828 (283)

Erratum to: Identification of Tn antigen O-GalNAc-expressing glycoproteins in human carcinomas using novel anti-Tn recombinant antibodies. [PDF]

Glycobiology, 2020
Matsumoto Y, Kudelka MR, Hanes MS, Lehoux S, Dutta S, Jones MB, Stackhouse KA, Cervoni GE, Heimburg-Molinaro J, Smith DF, Ju T, Chaikof EL, Cummings RD.   +12 more
europepmc   +1 more source

Investigation of IgM Monoclonal Paraprotein in Bone Marrow Aspiration: The Role of Immunophenotyping by Flow Cytometry in Selecting Cases for Molecular Testing for the p.MYD88 L265P Point Mutation

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Flow cytometry and real‐time quantitative polymerase chain reaction (qRT‐PCR) for MYD88 mutations (MYD88mt) are routinely performed on bone marrow aspirates during the diagnostic evaluation of IgM monoclonal paraproteinemia. The potential predictive value of immunophenotypic findings for molecular results, however, remains to be ...
Georgios Boutsikas, Konstantinos Agiannitopoulos, Elisavet Kouvidi, Myrto Katraki, Athanasios Papatheodorou, Anna Roussou, Nikolaos Paschalidis, Theodoros P. Vassilakopoulos, Ioannis Anagnostopoulos, Dimitra Sasaroli, Aglaia Dimitrakopoulou   +10 more
wiley   +1 more source

Identification of Tn antigen O-GalNAc-expressing glycoproteins in human carcinomas using novel anti-Tn recombinant antibodies. [PDF]

Glycobiology, 2020
Matsumoto Y, Kudelka MR, Hanes MS, Lehoux S, Dutta S, Jones MB, Stackhouse KA, Cervoni GE, Heimburg-Molinaro J, Smith DF, Ju T, Chaikof EL, Cummings RD.   +12 more
europepmc   +1 more source

Early Changes in Lymphocyte Counts Predict Clinical Outcomes in Hepatocellular Carcinoma Treated With Durvalumab Plus Tremelimumab

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Durvalumab plus tremelimumab (Dur/Tre) has shown promising efficacy in advanced hepatocellular carcinoma (HCC), but predictive biomarkers remain unclear. This study aimed to determine whether early changes in peripheral blood lymphocyte counts during Dur/Tre therapy can predict clinical outcomes.
Yuichi Honma, Shigeo Shimose, Takanori Ito, Issei Saeki, Joji Tani, Takanori Matsuura, Tetsu Tomonari, Yasuto Takeuchi, Nobuhito Taniki, Kyo Sasaki, Ryu Sasaki, Takeshi Hatanaka, Satoru Kakizaki, Naoki Yoshioka, Takehito Naito, Mamiko Takeuchi, Tetsuya Yasunaka, Masahiro Sakata, Hideki Iwamoto, Tomotake Shirono, Satoshi Itano, Norikazu Tanabe, Takafumi Yamamoto, Atsushi Naganuma, Yuki Kanayama, Hisamitsu Miyaaki, Sohji Nishina, Nobuhiro Nakamoto, Motoyuki Otsuka, Tetsuji Takayama, Yuzo Kodama, Hideki Kobara, Taro Takami, Hiroki Kawashima, Takumi Kawaguchi, Masaru Harada, Hepatology InVestigator Experts in Japan (HIVE‐J) Study Group   +36 more
wiley   +1 more source

Reactogenicity and Immunogenicity of RSV Vaccines in Immunocompromised Individuals With Hematological Malignancies

Transplant Infectious Disease, EarlyView.
In adults with hematologic malignancies, RSV vaccination was safe and induced antibody and T‐cell responses. However, antibody levels were lower and declined more rapidly than in healthy controls. While early immune responses were evident, reduced magnitude and durability of protection suggest the need for optimized vaccination strategies in this high ...
Alisse Hannaford, Zoe Swank, Simon D. van Haren, Natalie Izaguirre, Caitlin Syphurs, Zhou Lan, Bridget Yates, Urwah Kanwal, Grace Valentine, Ella Woehl, David Regan, Hannah Levine, Alexandra Tong, Maria Shehata, Fathia Oladipupo, Colleen Sedney, Kevin Ryff, Sanya Thomas, Joann Diray‐Arce, Xiaofang Li, Kimberly A. Dufresne, Lindsey A. Parisi, Aidan Eustace, Louise Hansen, David R. Walt, Ofer Levy, Amar Kelkar, Robert J. Soiffer, Vincent T. Ho, Lindsey R. Baden, Nicolas C. Issa, Ann E. Woolley, Amy C. Sherman   +32 more
wiley   +1 more source

AABB survey on directed blood donation practices

Transfusion, EarlyView.
Abstract Background Standardized guidance regarding the processes for collecting directed blood donations (DBD) is lacking, leading to variable practices. This study assessed laboratory, clinical, and charging practices for DBD collection in the United States and Canada. Study Design and Methods An electronic survey was distributed to United States and
Nabiha H. Saifee, Emily Coberly, Brian D. Adkins, Louise Helander, Nancy Robitaille, Laura K. Dilly, Lani Lieberman   +6 more
wiley   +1 more source

Scaling of prehospital blood: A model describing impact on U.S. blood donors, distribution and cost

Transfusion, EarlyView.
Abstract Background Prehospital transfusion improves survival in traumatic and medical hemorrhage, but the blood supply implications of scaling this capability across U.S. emergency medical services (EMS) systems are unclear. Study Design and Methods We developed an analytic model incorporating national estimates of prehospital transfusion demand, EMS ...
Pampee P. Young, David Wood, John B. Holcomb, Donald H. Jenkins, Matthew J. Levy   +4 more
wiley   +1 more source

Towards the Synthesis of a C-glycoside Tn Antigen

Towards the Synthesis of a C-glycoside Tn Antigen Advait Desai, Iraj Sadraei, John F. Trant Many biological processes including bacterial and viral infections (notably HIV and the flu), immunogenic responses, and cancer pathogenesis/metastasis are ...
Desai, Advait
core   +1 more source

Studies on a Sulfoxide-Bridged Tn Antigen Mimetic: Interaction with Macrophage Galactose Lectin and Inhibition of Sialyltransferase ST6GALNAC1. [PDF]

ACS Omega
Sodini A, Casali E, Travecedo MA, Marcelo F, Chiodo F, Rambaldi F, van Vliet SJ, Dall'Olio F, Nativi C.   +8 more
europepmc   +1 more source

Mass Spectrometric Mapping of Glycoproteins Modified by Tn-Antigen Using Solid-Phase Capture and Enzymatic Release. [PDF]

Anal Chem, 2020
Yang W, Ao M, Song A, Xu Y, Sokoll L, Zhang H.   +5 more
europepmc   +1 more source