Results 121 to 130 of about 621,376 (215)

Tumor-associated Tn and STn antigens: from molecular mechanism to precision diagnosis and treatment

Frontiers in Immunology
BackgroundAbnormal protein glycosylation is a key feature of tumors. Among the modifications, Tn antigen (GalNAcα1-Ser/Thr) and its sialylated derivative, STn antigen (Neu5Acα2-6GalNAcα1-O-Ser/Thr), are prominent tumor-associated carbohydrate antigens ...
Shuailong Zhao, Cegang Fu, Boya Gong, Hongyan Wu, Ruitao Zhang, Huili Cai, Haidan Chen, Haidan Chen   +7 more
doaj   +1 more source

Calorimetric Analysis of the Interplay between Synthetic Tn Antigen-Presenting MUC1 Glycopeptides and Human Macrophage Galactose-Type Lectin. [PDF]

Biochemistry, 2021
Beckwith DM, FitzGerald FG, Rodriguez Benavente MC, Mercer ER, Ludwig AK, Michalak M, Kaltner H, Kopitz J, Gabius HJ, Cudic M.   +9 more
europepmc   +1 more source

Tn-seq read counts at each Tn insertion site for all experimental conditions.

Tn-seq read counts at each Tn insertion site for all experimental conditions.
Sarah B. Namugenyi (18176930), Alisha M. Block (18176924), Anna D. Tischler (3074286), Parker C. Wiegert (18176927)   +3 more
core   +1 more source

Expression of Tn, sialosyl-Tn and T antigens in human foetal large intestine.

European journal of histochemistry : EJH, 2000
Tn, sialosyl-Tn and T antigens are simple mucin-type carbohydrate antigens that may be expressed in human neoplasies due to alteration of the glycoprotein biosynthetic pathway. Utilising specific monoclonal antibodies (HB-Tn1, HB-STn1 and HB-T1), we have investigated the expression of these simple mucin-type carbohydrate antigens in large intestine of ...
GROSSO, Maddalena, VITARELLI E, GIUFFRE', Giuseppe, TUCCARI, Giovanni, BARRESI, Gaetano   +4 more
openaire   +4 more sources

Tn Antigen [PDF]

, 2020
openaire   +1 more source

Sialyl Tn Antigen [PDF]

, 2020
openaire   +1 more source

The Synthesis of Natural Tn Antigen Carbohydrate Vaccines

The Synthesis of Natural Tn Antigen Carbohydrate Vaccines Aiyireti (Dina) Dilinaer, Michael R. Reynolds, S. Iraj Sadraei, John F. Trant The immune system plays an important role in defending the human body against diseases and invasion of pathogens. When
Reynolds, Michael R., Dilinaer, Aiyireti, Trant, John F., Sadraei, Seyed Iraj   +3 more
core   +1 more source

Design, synthesis, and initial immunological evaluation of glycoconjugates based on saponin adjuvants and the Tn antigen.

Chem Commun (Camb), 2021
Fuentes R, Aguinagalde L, Sacristán N, Fernández-Tejada A.   +3 more
europepmc   +1 more source

Targeting the cancer glycocalyx in salivary duct carcinoma: tumor‐associated mucin 1 (Tn‐MUC1) as a novel cell surface marker

The Journal of Pathology: Clinical Research
Despite the use of targeted drugs for human epidermal growth factor receptor type 2 (HER2)‐positive salivary duct carcinoma (SDC) treatment, the overall prognosis for SDC remains poor.
Masashi Kuroki, Ryo Kawaura, Hiroyuki Tomita, Hirofumi Shibata, Toshimitsu Ohashi, Tomohiko Ishikawa, Hideshi Okada, Akira Hara, Takenori Ogawa   +8 more
doaj   +1 more source

Tn Antigen Antibody [PDF]

, 2020
openaire   +1 more source