Immunohistochemical study of Tn, sialosyl-Tn and T antigens in human meningiomas.
European journal of histochemistry : EJH, 1998 Since an aberrant glycosylation associated with abnormal expression of cell surface carbohydrates has been described in many human tumours, we have investigated the expression of simple mucintype carbohydrate antigens (Tn, sialosyl-Tn and T) in 30 formalin-fixed paraffin-embedded surgical specimens of primary meningiomas, subdivided according to the ...
GIUFFRE', Giuseppe +3 more
openaire +2 more sources
Sialyl-Tn Antigen-Imprinted Dual Fluorescent Core-Shell Nanoparticles for Ratiometric Sialyl-Tn Antigen Detection and Dual-Color Labeling of Cancer Cells. [PDF]
ACS Appl Nano Mater, 2022 Jiang S +6 more
europepmc +1 more source
ST6GalNAc-I controls expression of sialyl-Tn antigen in gastrointestinal tissues
, 2011 Sialyl-Tn is a simple mucin-type carbohydrate antigen aberrantly expressed in gastrointestinal adenocarcinomas and in the precursor lesion intestinal metaplasia. Sialyl-Tn tumour expression is an independent indicator of poor prognosis.
Vogel, Lotte K +22 more
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Using the Tn Antigen as an Immunotherapeutic Cancer Treatment
Viable, Healthy and Safe CommunitiesImmunotherapeutic cancer treatment is a way of having the body's immune system attack cancer cells in order to slow growth and/or prevent metastasis.
Piazza, Sabrina M
core +1 more source
Transplant nephrectomy - A single-center experience
Saudi Journal of Kidney Diseases and Transplantation, 2015 Transplant nephrectomy (TN) is associated with significant morbidity and mortality and influences the outcome of subsequent renal transplantation. The aim of this study was to identify the reasons for TN in a single transplant center in the United ...
Arun Ariyarathenam +2 more
doaj +1 more source
Lung Tumor Cells with Different Tn Antigen Expression Present Distinctive Immunomodulatory Properties. [PDF]
Int J Mol Sci, 2022 Costa VD +9 more
europepmc +1 more source
Phage Display Reveals VLRB-Mediated Recognition of Minimal Tumor Glycan Antigen Sialyl-Tn
Current Issues in Molecular BiologySialyl-Tn (sTn) is a tumor-associated carbohydrate antigen (TACA) abundantly expressed by various types of carcinomas. While conventional antibody-based platforms have traditionally been used for the detection and targeting of sTn, alternative binding ...
Mark Rickard N. Angelia +8 more
doaj +1 more source
A previously uncharacterized O-glycopeptidase from Akkermansia muciniphila requires the Tn-antigen for cleavage of the peptide bond. [PDF]
J Biol Chem, 2022 Medley BJ +9 more
europepmc +1 more source
Curcumin-mediated transcriptional regulation of human N-acetylgalactosamine-α2,6-sialyltransferase which synthesizes sialyl-Tn antigen in HCT116 human colon cancer cells. [PDF]
Front Mol Biosci, 2022 An SY +5 more
europepmc +1 more source
, 2000 International audienceGlycopeptides containing a tumor-associated carbohydrate antigen (mono-, tri- or hexa-Tn antigen) as a B-cell epitope and a CD4+ T-cell epitope (PV: poliovirus or TT: tetanus toxin) were prepared for immunological studies.
Deriaud, E. +6 more
core +1 more source