Results 211 to 220 of about 10,050,273 (238)
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Expression of TRAIL (TNF-related apoptosis-inducing ligand) receptors in cervical cancer
International Journal of Gynecological Cancer, 2000Apoptosis is an intrinsic and fundamental biologic process that plays a critical role in the normal development of multicellular organisms and in the maintainance of tissue homeostasis. Some of the well known regulators of apoptosis are cytokines of the tumor necrosis factor (TNF) ligand family, such as Fas ligand (Fas L) and TNF, which induce ...
H. S., Ryu +5 more
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TNF-related apoptosis-inducing ligand (TRAIL) in rheumatoid arthritis: what’s new?
Clinical and Experimental Medicine, 2012TNF-related apoptosis-inducing ligand (TRAIL) is a type II transmembrane protein of the TNF superfamily that serves as an extracellular signal that triggers programmed cell death in tumor cells, without affecting normal cells. Recently, scientists have turned their attention to the emerging role of TRAIL in immune and autoimmune responses.
NEVE, ANNA +2 more
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TNF-Related Apoptosis-Inducing Ligand Receptor 1 in Patients With Ankylosing Spondylitis
JCR: Journal of Clinical Rheumatology, 2019Objectives Tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) belongs to the tumor necrosis factor (TNF) superfamily and is reported to play a role in autoimmune diseases. In this study, we aimed to measure serum TRAIL receptor 1 (TRAIL-R1) concentration and assess any phenotypic relationship in patients with ...
Yazici, AYTEN +5 more
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2007
The host response to pathogenic insults involves complex inflammatory responses and cellular immune reactions. While these are central to host defense and vital to clearing dangerous invaders, they are often associated with nonspecific injury to nearby tissue.
Thomas A, Ferguson, Thomas S, Griffith
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The host response to pathogenic insults involves complex inflammatory responses and cellular immune reactions. While these are central to host defense and vital to clearing dangerous invaders, they are often associated with nonspecific injury to nearby tissue.
Thomas A, Ferguson, Thomas S, Griffith
openaire +2 more sources
The role of TNF related apoptosis-inducing ligand in neurodegenerative diseases.
Cellular & molecular immunology, 2005A hallmark of all forms of neurodegenerative diseases is impairment of neuronal functions, and in many cases neuronal cell death. Although the etiology of neurodegenerative diseases may be distinct, different diseases display a similar pathogenesis, for example abnormal immunity within the central nervous system (CNS), activation of macrophage ...
Y, Huang +4 more
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Blood, 2000
The impact of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) on normal hematopoietic development was investigated using adult peripheral blood CD34(+) hematopoietic progenitor cells, induced to differentiate along the erythroid, megakaryocytic, granulocytic, and monocytic lineages by the addition of specific cytokine cocktails ...
ZAMAI L +8 more
openaire +4 more sources
The impact of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) on normal hematopoietic development was investigated using adult peripheral blood CD34(+) hematopoietic progenitor cells, induced to differentiate along the erythroid, megakaryocytic, granulocytic, and monocytic lineages by the addition of specific cytokine cocktails ...
ZAMAI L +8 more
openaire +4 more sources
The structure of the death receptor 4–TNF-related apoptosis-inducing ligand (DR4–TRAIL) complex
Acta Crystallographica Section F, Structural Biology Communications, 2015Steven Sheriff +2 more
exaly