Results 261 to 270 of about 1,230,752 (303)
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Levels of TNF, TNF autoantibodies and soluble TNF receptors in patients with bronchial asthma
Journal of Asthma, 2013The aim of the study was to evaluate the potential contribution made by tumor necrosis factor (TNF) autoantibodies to the pathogenesis of bronchial asthma (BA).We used affinity chromatography methods and a magnetic separation procedure to purify human autoantibodies specific to TNF.
Elena Alexeevna, Golikova +4 more
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TNF/TNF Receptor 1-Mediated Apoptosis in Hepatocytes
2010Tumor necrosis factor (TNF)-alpha has been implicated in the induction of hepatocyte apoptosis in a variety of liver diseases including viral hepatitis, alcoholic hepatitis, ischemia/reperfusion injury, fulminant hepatic failure, cholestatic liver injury, and cancer.
Hyun-Ae, Eum, Timothy R, Billiar
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Origin and evolution of TNF and TNF receptor superfamilies
Developmental & Comparative Immunology, 2011The tumor necrosis factor superfamily (TNFSF) and the TNF receptor superfamily (TNFRSF) have an ancient evolutionary origin that can be traced back to single copy genes within Arthropods. In humans, 18 TNFSF and 29 TNFRSF genes have been identified.
Gregory D, Wiens, Gavin W, Glenney
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Death by TNF: a road to inflammation
Nature Reviews Immunology, 2022Geert van Loo, Mathieu J M Bertrand
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Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death
Cell, 2021Justin Taft +2 more
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The TNF receptor in TNF-mediated cytotoxicity.
Natural immunity and cell growth regulation, 1989The in vitro cytotoxic capacity (if not every pleiotropic property) of tumor necrosis factor (TNF) begins by interaction with specific high affinity cell surface receptors. The characterization of receptors and ligand kinetics is reviewed in relationship to cytotoxicity.
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Clinical targeting of the TNF and TNFR superfamilies
Nature Reviews Drug Discovery, 2013Michael Croft +2 more
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