Results 91 to 100 of about 22,212 (273)

Hapten-conjugated polymeric nanocarriers produced by Flash NanoPrecipitation induce small molecule-specific antibodies in vivo [PDF]

RSC Pharmaceutics
Vaccines that induce antibodies specific against small molecules are desirable for a range of applications, including as a tool against the opioid epidemic. Many small molecules are not immunogenic due to their low molecular weight, but can be conjugated
Mojhdeh Baghbanbashi, Ryan Burnett, David M. Gooden, Frank S. Vago, Herman F. Staats, Brandi Johnson-Weaver, Kurt Ristroph   +6 more
doaj   +1 more source

A colorimetric and fluorescent chemosensor for the detection of an explosive--2,4,6-trinitrophenol (TNP).

Chemical Communications, 2011
A fluorescent and colorimetric receptor (L) for specific recognition of TNP was described. The origins of this remarkable affinity was disclosed by the crystal structure of corresponding host-guest complex L·TNP.
Yu Peng, Ai-Jiang Zhang, Ming Dong, Ya-Wen Wang   +3 more
semanticscholar   +1 more source

Fluorescence spectra of TNP-ATP bound to M. leprae HSP18.

, 2015
(A) Fluorescence emission spectra of TNP-ATP alone (trace 1); TNP-ATP+HSP18 (trace 2); Addition of 0.25 mM ATP to the HSP18-TNP-ATP complex (trace 3). Protein concentration used was 2.5 μM and TNP-ATP concentration was 2.5 μM.
Sandip Kumar Nandi (713237), Ayon Chakraborty (713238), Anirban Bhunia (116360), Alok Kumar Panda (335270), Sougata Sinha Ray (713239), Rajiv Kumar Kar (473120), Ashis Biswas (335275)   +6 more
core   +1 more source

The angiogenic inhibitor TNP-470 decreases caloric intake and weight gain in high fat fed mice

Obesity, 2012
The angiogenic inhibitor TNP‐470 attenuates high‐fat diet‐induced obesity; however, it is not clear how the compound alters energy balance to prevent weight gain.
H. White, Anthony J. Acton, R. Considine
semanticscholar   +1 more source

The 2027 BCPT Perspectives on Studies Involving Natural Products, Traditional Chinese Medicine and Systems Pharmacology

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 5, November 2026.
ABSTRACT Natural products, including isolated compounds, complex extracts, traditional medicinal preparations and marine, microbial, fungal and animal‐derived materials, remain important sources of therapeutic agents and pharmacological discovery.
Pernille Tveden‐Nyborg, Baoxue Yang, Gökay Albayrak, Ulf Simonsen, Jens Lykkesfeldt   +4 more
wiley   +1 more source

Enhanced photo/chemo combination efficiency against bladder tumor by encapsulation of DOX and ZnPC into in situ-formed thermosensitive polymer hydrogel

International Journal of Nanomedicine, 2018
Zhongming Huang, He Xiao, Xiangyun Lu, Weigang Yan, Zhigang Ji Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China Background: Chemotherapy after ...
Huang Z, Xiao H, Lu X, Yan W, Ji Z
doaj  

Enhanced anti-tumor activity and safety profile of targeted nano-scaled HPMA copolymer-alendronate-TNP-470 conjugate in the treatment of bone malignances

Biomaterials, 2011
Bone neoplasms, such as osteosarcoma, exhibit a propensity for systemic metastases resulting in adverse clinical outcome. Traditional treatment consisting of aggressive chemotherapy combined with surgical resection, has been the mainstay of these ...
Ehud Segal, H. Pan, L. Benayoun, P. Kopec̆ková, Y. Shaked, J. Kopeček, R. Satchi-Fainaro   +6 more
semanticscholar   +1 more source

Hydro‐ and Lipophilicity of Molecular‐Size‐Controlled Hydrogel Drug Carriers

Advanced Materials Technologies, Volume 11, Issue 20, 21 October 2026.
We investigate nano‐sized hydrogel drug carriers with tailored hydro‐ and lipophilicity. We design their encapsulation and structure‐forming capabilities and follow them in real time during fabrication using time‐resolved and in situ grazing incidence x‐ray scattering.
Elisabeth Erbes, Naireeta Biswas, Calvin J. Gavillet, Matthias Schwartzkopf, Krishnayan Basuroy, Qing Chen, Andrei Chumakov, Susann Frenzke, Marc Gensch, Korneliya Gordeyeva, Patrycja Kielb, Sonja Kirchner, Volker Körstgens, Peter Müller‐Buschbaum, Henrike M. Müller‐Werkmeister, Jan Rubeck, Sreevidya Thekku Veedu, Jose de Jesus Velazquez‐Garcia, Vivian Waclawek, Daniel Söderberg, Stephan V. Roth, Simone Techert   +21 more
wiley   +1 more source

Estudio empírico del trastorno narcisista de la personalidad (TNP) [PDF]

, 2008
La investigación pretende profundizar en la descripción y evaluación del Trastorno Narcisista de la Personalidad (TNP). En primer lugar, se define el TNP según cuatro rasgos: autoimagen distorsionada; falta de empatía, hipersensibilidad a la evaluación ...
Millán Vázquez-Torre, Genoveva, Trechera Herreros, José Luis, Morales Fernández, Emilio   +2 more
core  

The role of TNP-Nucleotides, LYS492 and CA²⁺chelators in the skeletal muscle sarcoplasmic reticulum CA²⁺atpase cycle [PDF]

, 1998
In the first part of this study, the kinetics of decay of TNP-nucleotide superfluorescence was investigated with a view to understanding the role of nucleotides and Lys492 in later steps in the catalytic cycle of the skeletal muscle Ca²⁺ATPase.
Wichmann, Janine
core   +1 more source