Results 81 to 90 of about 12,194 (224)

Inhibition of vessel permeability by TNP-470 and its polymer conjugate, caplostatin

, 2005
SummaryAngiogenesis inhibitors, such as TNP-470 and the nontoxic HPMA copolymer-TNP-470 (caplostatin), are emerging as a class of anticancer drugs. We report that TNP-470 and caplostatin inhibit vascular hyperpermeability of tumor blood vessels as well ...
Janice A. Nagy, Short, Sarah M., Dvorak, Harold F., Mukhopadhyay, Debabrata, Roni Mamluk, Ann M. Dvorak, Nagy, Janice A., Ling Wang, Harold F. Dvorak, Mark Puder, Satchi-Fainaro, Ronit, Mamluk, Roni, Feng, Dian, Wang, Ling, Puder, Mark, Dvorak, Ann M., Folkman, Judah, Ronit Satchi-Fainaro, Debabrata Mukhopadhyay, Dian Feng, Sarah M. Short, Judah Folkman   +21 more
core   +1 more source

Enhanced photo/chemo combination efficiency against bladder tumor by encapsulation of DOX and ZnPC into in situ-formed thermosensitive polymer hydrogel

International Journal of Nanomedicine, 2018
Zhongming Huang, He Xiao, Xiangyun Lu, Weigang Yan, Zhigang Ji Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China Background: Chemotherapy after ...
Huang Z, Xiao H, Lu X, Yan W, Ji Z
doaj  

Sodium-Doped Carbon Dots as Fluorescent Sensor for Highly Selective Detection of TNP Explosives in the Environment

Nanomanufacturing
Given the environmental hazards of 2,4,6-trinitrophenol (TNP) and the limitations of existing detection methods, sodium-doped fluorescent carbon dots (Na-CDs) were successfully synthesized via a one-step hydrothermal method using citric acid and ascorbic
Tianyu Gao, Xuehua Sun, Hongmei Chai
doaj   +1 more source

The Effect of IFN-γ, Alum and Complete Freund Adjuvant on TNP-KLH Induced Ig.G1, IgE and IgG2a Responses in Mice

Mediators of Inflammation, 1994
Adjuvants are considered to play an important role in directing the isotype and amount of antibodies produced upon immunization by conducting the development of either Th-1 or Th-2 cells upon T-cell stimulation.
R. van Ommen, A. E. C. M. Vredendaal, M. de Gooyer, A. van Oudenaren, H. F. J. Savelkoul   +4 more
doaj   +1 more source

TNP [N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine] ameliorates diet induced obesity and insulin resistance via inhibition of the IP6K1 pathway

Molecular Metabolism, 2016
Objective: Obesity and type 2 diabetes (T2D) lead to various life-threatening diseases such as coronary heart disease, stroke, osteoarthritis, asthma, and neurodegeneration.
Sarbani Ghoshal, Qingzhang Zhu, Alice Asteian, Hua Lin, Haifei Xu, Glen Ernst, James C. Barrow, Baoji Xu, Michael D. Cameron, Theodore M. Kamenecka, Anutosh Chakraborty   +10 more
doaj   +1 more source

Water-mediated protein-fluorophore interactions modulate the affinity of an ABC-ATPase/TNP-ADP complex

, 2008
TNP-modified nucleotides have been used extensively to study protein-nucleotide interactions. In the case of ABC-ATPases, application of these powerful tools has been greatly restricted due to the significantly higher affinity of the TNP-nucleotide for ...
Smits, Sander H J, Schmitt, Lutz, Oswald, C., Holland, I. B., Jenewein, Stefan, Jenewein, S., Oswald, Christine, Schmitt, L., Smits, S. H., Holland, I Barry   +9 more
core   +1 more source

Fluorescence spectra of TNP-ATP bound to M. leprae HSP18.

, 2015
(A) Fluorescence emission spectra of TNP-ATP alone (trace 1); TNP-ATP+HSP18 (trace 2); Addition of 0.25 mM ATP to the HSP18-TNP-ATP complex (trace 3). Protein concentration used was 2.5 μM and TNP-ATP concentration was 2.5 μM.
Sandip Kumar Nandi (713237), Ayon Chakraborty (713238), Anirban Bhunia (116360), Alok Kumar Panda (335270), Sougata Sinha Ray (713239), Rajiv Kumar Kar (473120), Ashis Biswas (335275)   +6 more
core   +1 more source

TNP implementation strategy survey.

BackgroundHigh-quality implementation evaluations report on intervention fidelity and adaptations made, but a practical process for evaluating implementation strategies is needed.
Chelsea Leonard (8601954), Mary Nunnery (18127160), Christine Jones (571089), Brigid Connelly (8601948), Heather Gilmartin (10273329), Borsika Rabin (3426470), Robert E. Burke (5420657), Ashlea Wills (11129571), Lynette Kelley (8601960)   +8 more
core   +1 more source

Priming of peripheral lymph node B cells with TNP-Ficoll: Role of lymphokines in B cell differentiation

, 1992
We have previously shown that peripheral lymph node (PLN) B lymphocytes of adult DBA/ 25 mice failed to make an antibody responseto type 2 antigen TNP-Ficoll, but exhibited a good antibody response to type 1 antigen TNP-BruceNa abortus.
S.Niranjan Goud, Alan M. Kaplan, Kaplan, Alan M., Bondada, Subbarao, Bondada Subbarao, Goud, S. Niranjan   +5 more
core   +1 more source

Smartphone enabled machine learning approach assisted copper (II) quantification and opto-electrochemical explosive recognition by Aldazine-functionalized chemobiosensor

Sensors and Actuators Reports
An Aldazine-based optoelectrochemical sensor, BMH (1-(quinolin-4-ylmethylene)hydrazono)methyl)naphthalen-2-ol) has been introduced herein for selective detection of aqueous copper (Cu2+) and 2, 4, 6-Trinitrophenol (TNP) at an ultra-low level detection ...
Mohit Kumar Chattopadhyay, Amita Mondal, Abhijit Hazra, Swarup Kumar Tarai, Bishwajit Singh Kapoor, Sudit S. Mukhopadhyay, Surya Sarkar, Priyabrata Banerjee   +7 more
doaj   +1 more source