Results 11 to 20 of about 3,533 (184)
Binding of TNP‐ATP and TNP‐ADP to the non‐catalytic sites of Escherichia coli F1‐ATPase [PDF]
FEBS Letters, 1997 Using site‐directed‐tryptophan fluorescence, parameters for equilibrium binding of (Mg)TNP‐ATP and (Mg)TNP‐ADP to non‐catalytic sites of Escherichia coli F1‐ATPase were determined. All three non‐catalytic sites showed the same affinity for MgTNP‐ATP (K d=0.2 μM) or MgTNP‐ADP (K d=6.5 μM) whereas even at concentrations of 100 μM no binding of ...
Weber, Joachim, Senior, Alan E
openaire +4 more sources
In-vitro characterisation of a novel antimicrobial agent, TNP-2092, against Helicobacter pylori clinical isolates [PDF]
Swiss Medical Weekly, 2018 BACKGROUND AND OBJECTIVES TNP-2092 is a novel dual-action lead compound consisting of rifamycin SV and 4H-4-oxo-quinolizine pharmacophores, with a broad spectrum of antibacterial activities.
Ben Wang +10 more
doaj +2 more sources
A trinitrophenyl(TNP)-poly-L-lysine-horseradish peroxidase conjugate for the detection of anti-TNP antibodies in vivo. [PDF]
Journal of Histochemistry & Cytochemistry, 1985 A new conjugate for the detection of anti-trinitrophenyl(TNP) antibodies was developed to study the localization pattern of specific antibody containing cells and extracellular antibody in vivo. By means of a bridging molecule, poly-L-lysine, nine TNP groups and six horseradish peroxidase (HRP) groups were joined in one conjugate.
E, Claassen, N, Van Rooijen
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TNP and its analogs: Modulation of IP6K and CYP3A4 inhibition [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 Inositol hexakisphosphate kinase (IP6K) is an important mammalian enzyme involved in various biological processes such as insulin signalling and blood clotting. Recent analyses on drug metabolism and pharmacokinetic properties on TNP (N2-(m-trifluorobenzyl), N6-(p-nitrobenzyl)purine), a pan-IP6K inhibitor, have suggested that it may inhibit cytochrome ...
Seulgi Lee +14 more
openaire +5 more sources
, 2015 Jean Vilar cristallise un paradoxe : il représente une figure du passé et incarne tout à la fois l’expression d’une vérité présente, puisque l’on constate la résurgence des questions qu’il nous a léguées.
Fleury, Laurent
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Acta Pharmaceutica Sinica B, 2012 Thienorphine (TNP) is a new partial opioid agonist currently developed as a promising drug candidate with the intended clinical indication for the treatment of opioid dependence.
Jingting Deng +4 more
doaj +1 more source
Binding of Trinitrophenol (TNP)-specific immunoglobulin free light chain (Ig-fLC) to TNP-conjugated ovalbumin (TNP-OVA) or TNP-conjugated bovine serum albumin (TNP-BSA) detected by immunoblotting. [PDF]
, 2013 TNP-coated proteins, TNP-BSA (lane 3–5) or TNP-OVA (lane 8–10), or unconjugated controls (lane 2: BSA and 7:OVA) were subjected to SDS-PAGE and subsequently electroblotted to PVDF membrane. Membrane was incubated with TNP-kappa Ig-fLC (2 µg/ml) and bound
Bart R. Blokhuis (315023) +5 more
core +1 more source
Investigating the effect of Nigella sativa on the testicular function of first-generation offspring of mice treated with titanium oxide nanoparticles [PDF]
Avicenna Journal of Phytomedicine, 2023 Objective: Nanoparticles include primary particles with at least one of their dimensions being less than 100 nm. The goal of this research was to determine the possible protective role of Nigella sativa (NS) against toxic effects mediated by titanium ...
Morteza Abouzaripour +4 more
doaj +1 more source
Clinical Ophthalmology, 2023 Majid Moshirfar,1– 3 Devon Hori Harvey,4 Qiancheng Wang,5 Carter J Payne,1,6 David G West,7 Phillip C Hoopes1 1Hoopes Vision Research Center, Hoopes Vision, Draper, UT, USA; 2John A. Moran Eye Center, University of Utah School of Medicine, Salt Lake City,
Moshirfar M +5 more
doaj
Chemical Engineering Journal Advances, 2021 Visual and selective detection of 2,4,6-trinitrophenol (TNP) for public and environmental protection is an extremely urgent issue and challenge. Herein, a novel fluorescence polyurethane (FPU) has been successfully synthesized and exploited for selective
GAO Shan +7 more
doaj +1 more source