Results 31 to 40 of about 3,533 (184)

TNP-470 skews DC differentiation to Th1-stimulatory phenotypes and can serve as a novel adjuvant in a cancer vaccine

Blood Advances, 2018
: Fumagillin is an antiangiogenic and antineoplastic fungal natural product, and TNP-470 is one of its most potent analogs. Decades of studies revealed that TNP-470 has potent anticancer activities via destruction of neovasculature.
Derek Hoi-Hang Ho, Roger Hoi-Fung Wong
doaj   +1 more source

Carbon Dot Functionalized Papers for the Selective Detection of 2,4,6-Trinitrophenol in Aqueous Solutions

Advances in Materials Science and Engineering, 2021
The development of probes for the testing of the carcinogenic pollutant 2,4,6-trinitrophenol (TNP) is of great importance for environmental protection and human health.
Wenli Peng, Li Gan, Weihan Li, Shixiong Deng   +3 more
doaj   +1 more source

Specific IgM antibodies to TNP-OVA are only detected in the circulation after an i.v. injection of TNP-OVA with a prior injection of LPS. [PDF]

, 2013
The antibody response was only present when LPS preceded the injection of TNP-OVA(uninterrupted line). Dashed line shows the IgM levels in plasma after injection of TNP-OVA only.
Jan van der Vliet (95826), Ruud M. Buijs (95828), Inge Huitinga (376749), Carolina Escobar (21974), Mari-Laure Garidou (376747)   +4 more
core   +1 more source

A compare between myocardial topical negative pressure levels of -25 mmHg and -50 mmHg in a porcine model

BMC Cardiovascular Disorders, 2008
Background Topical negative pressure (TNP), widely used in wound therapy, is known to stimulate wound edge blood flow, granulation tissue formation, angiogenesis, and revascularization.
Hlebowicz Joanna, Gesslein Bodil, Mokhtari Arash, Paulsson Per, Lindstedt Sandra, Malmsjö Malin, Ingemansson Richard   +6 more
doaj   +1 more source

Anti-TNP monoclonal antibodies as reagents for enzyme immunoassay (ELISA) [PDF]

, 2015
The aim of this study was to produce anti-TNP monoclonal antibodies (MAbs) that could be conjugated and used for the detection of antigen-antibody reactions, in which the antigen specific-antibody had been previously bound to trinitrophenyl (TNP).
Leo, P, Oliveira, M S, Oliveira, MS, Augusto, E F, Tamashiro, W M, Ucelli, P, Tamashiro, WMSC, Augusto, EFP   +7 more
core   +1 more source

TMA-TNP Design v1 [PDF]

, 2020
Human Tumor Atlas Tissue MicroArrary TNP (TMA-TNP) The Tissue MicroArray (TMA) TNP will extend the SARDANA-TNP characterization and analytics methodologies for evaluation and validation on a large array of breast tumor samples that provide a broad spectrum of disease state and subtype.
Heidi S Feiler, Koei Chin
openaire   +1 more source

No hypoperfusion is produced in the epicardium during application of myocardial topical negative pressure in a porcine model

Journal of Cardiothoracic Surgery, 2007
Background Topical negative pressure (TNP), commonly used in wound therapy, has been shown to increase blood flow and stimulate angiogenesis in skeletal muscle.
Malmsjö Malin, Lindstedt Sandra, Ingemansson Richard   +2 more
doaj   +1 more source

Training registered nurses to conduct pre-implementation assessment to inform program scale-up: an example from the rural Transitions Nurse Program

Implementation Science Communications, 2021
Objectives Adapting evidence-based practices to local settings is critical for successful implementation and dissemination. A pre-implementation assessment evaluates local context to inform implementation, but there is little published guidance for ...
Chelsea Leonard, Heather Gilmartin, Marina McCreight, Lynette Kelley, Ashlea Mayberry, Robert E. Burke   +5 more
doaj   +1 more source

Preparation of Transparent TiO₂ Nanoporous Coating with Highly Photocatalytic Activity by Anodizing Ti Film with Loose Structure

Cailiao gongcheng, 2016
The Ti film with special structure was deposited onto glass substrate by magnetron sputtering, then via the process of electrochemical anodization and annealing, a transparent TiO2 nanoporous coating (denoted as TNP) with high photocatalytic activity can
LIANG Yin, LI Peng, PEI Wang, DUAN Jin-hui, HUANG Feng, ZHAO Kun-yu   +5 more
doaj   +1 more source

NAD+ Metabolism Licenses Zygotic Genome Activation via PARP7‐Mediated ADP‐Ribosylation of UHRF1 in Mouse Early Embryos

Advanced Science, EarlyView.
This study uncovers a metabolic‐epigenetic axis licensing zygotic genome activation (ZGA) in mouse embryos. A developmental decline in NAD+ levels activates PARP7, which mono‐ADP‐ribosylates and stabilizes UHRF1. This modification promotes the establishment of permissive histone acetylation marks, thereby facilitating timely ZGA.
Guangyi Cao, Ziqi Zhang, Anqi Chen, Yanbo Liu, Yuling Lin, Lina Yu, Ruixin Shi, Aolei Guo, Yan Mao, Ganggui Lou, Chaojun Li, Luhong Wen, Guijun Yan, Haixiang Sun   +13 more
wiley   +1 more source