Results 31 to 40 of about 46,460 (216)

Early preclinical screening using zebrafish (Danio rerio) reveals the safety of the candidate anti-inflammatory therapeutic agent TnP

open access: yesToxicology Reports, 2021
The patented anti-inflammatory peptide TnP had its effectiveness recently confirmed in vivo in a murine model of multiple sclerosis and asthma. In this work, the safety of the TnP was evaluated in investigative toxicology tests using zebrafish (Danio ...
João Batista-Filho   +7 more
doaj   +1 more source

BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival [PDF]

open access: yes, 2015
B cell activating factor (BAFF) stimulation of the BAFF receptor (BAFF-R) is essential for the homeostatic survival of mature B cells. Earlier in vitro experiments with inhibitors that block MEK 1 and 2 suggested that activation of ERK 1 and 2 MAP ...
Jacque, E   +3 more
core   +1 more source

Reconfiguration of Multiphase Coacervate Droplets Into Self‐Regulated Nested Artificial Cells

open access: yesAngewandte Chemie, EarlyView.
Living cells advance functionality through spatiotemporal sub‐compartmentalization and internal organization. Herein, we develop a self‐regulated artificial cell by transforming a membrane‐less multiphase coacervate droplet (MCD) into a membranized, structurally reinforced nested coacervate vesicle (NCV).
Zhuping Yin   +4 more
wiley   +2 more sources

TNP-470 skews DC differentiation to Th1-stimulatory phenotypes and can serve as a novel adjuvant in a cancer vaccine

open access: yesBlood Advances, 2018
: Fumagillin is an antiangiogenic and antineoplastic fungal natural product, and TNP-470 is one of its most potent analogs. Decades of studies revealed that TNP-470 has potent anticancer activities via destruction of neovasculature.
Derek Hoi-Hang Ho, Roger Hoi-Fung Wong
doaj   +1 more source

Carbon Dot Functionalized Papers for the Selective Detection of 2,4,6-Trinitrophenol in Aqueous Solutions

open access: yesAdvances in Materials Science and Engineering, 2021
The development of probes for the testing of the carcinogenic pollutant 2,4,6-trinitrophenol (TNP) is of great importance for environmental protection and human health.
Wenli Peng   +3 more
doaj   +1 more source

Universal functions for taylor shifts [PDF]

open access: yes, 1996
In this paper a new sort of operators, the Taylor shifts, is introduced. They appear as a generalization of weighted backward shifts on the spaces of entire functions and of holomorphic functions in the unit disk.
Bernal González, Luis
core   +1 more source

A compare between myocardial topical negative pressure levels of -25 mmHg and -50 mmHg in a porcine model

open access: yesBMC Cardiovascular Disorders, 2008
Background Topical negative pressure (TNP), widely used in wound therapy, is known to stimulate wound edge blood flow, granulation tissue formation, angiogenesis, and revascularization.
Hlebowicz Joanna   +6 more
doaj   +1 more source

Regulated progression of B lymphocyte differentiation from cultured fetal liver. [PDF]

open access: yes, 1987
Lymphoid fetal liver cultures (LFLC) are long-term, nontransformed cultures of early B lymphoid lineage cells which appear developmentally blocked at the pre-B stage in vitro.
Denis, KA, Dorshkind, K, Witte, ON
core   +2 more sources

TNP‐470 Is an Effective Antimicrosporidial Agent [PDF]

open access: yesThe Journal of Infectious Diseases, 1998
Therapy for microsporidia, which cause diarrhea and a wasting syndrome in persons with AIDS, has had limited success. Fumagillin, a naturally secreted water-insoluble antibiotic, has in vitro activity against microsporidia and has been used successfully in the treatment of superficial keratitis in patients with AIDS, but systemic therapy has been ...
C, Coyle   +4 more
openaire   +2 more sources

Structure of Multi-Anyon Wavefunctions

open access: yes, 1993
Symmetries of multi-anyon wavefunctions are analysed with the help of a second quantized formulation. Analogues of Slater determinants are constructed.
Banerjee   +17 more
core   +1 more source

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