Results 51 to 60 of about 12,194 (224)

Real-time analysis of TNP-specific Ig-fLC binding to TNP-BSA coated SPR chips.

, 2013
Increasing concentrations of Ig-fLC (300 ng, 900 ng, 1.8 µg, 2.7 µg and 3.6 µg per CM5 sensor chip) resulted in increased binding curves (A). Administration of TNP-IgE (3.6 µg) resulted in significant binding to the TNP-coated surface and saturation ...
Bart R. Blokhuis (315023), Marco Thio (315020), Tom Groot Kormelink (315021), Frans P. Nijkamp (315024), Marcel J. Fischer (315022), Frank A. Redegeld (315025)   +5 more
core   +1 more source

TnP Peptide Suppresses Experimental Autoimmune Encephalomyelitis (EAE) in a Preclinical Mouse Model

Frontiers in Immunology, 2022
TnP is a family of patented synthetic peptides which is in a preclinical development stage with valuable potential therapeutic indication for multiple sclerosis (MS), an autoimmune demyelinating disease of the central nervous system (CNS).
Carla Lima, Adolfo Luis Almeida Maleski, Jefferson Thiago Gonçalves Bernardo, Vitor Cataldi Zelli, Evilin Naname Komegae, Monica Lopes-Ferreira   +5 more
doaj   +1 more source

Pediatric Developmental Safety Assessment: Are We Ready for the Next Thalidomide?

Clinical Pharmacology &Therapeutics, EarlyView.
Pediatric drug development has achieved remarkable success in the last 20 years with over 1,000 products studied in pediatric patients. This success has been driven in part by an increased understanding of pediatric disease processes. The aspect that has been largely overlooked is the potential adverse effect of new drugs on pediatric developmental ...
Gilbert J. Burckart, Susan M. Abdel‐Rahman, Gelareh Abulwerdi, Sherbet Samuels, Rebecca Racz, Mohamed A. Mohamoud, Nicholas P. Tatonetti   +6 more
wiley   +1 more source

Dual-enzyme activated theranostic nanoparticles for image-guided glioblastoma therapy

Scientific Reports
Matrix metalloproteinase-14 (MMP-14) and Cathepsin-B (Cat-B) are overexpressed in glioblastoma (GBM) and not normal brain, making them promising targets for prodrug activation.
Zahra Shokri Varniab, Edwin Chang, Jie Wang, Ramesh Duwa, Vidyani Suryadevara, Wei Wu, Manoj Kumar, Tie Liang, Zubeda Khatoon, Goreti Ribeiro Morais, Robert Falconer, Yifeng Shi, Grigory Tikhomirov, Kerem Nernekli, Laura Jean Pisani, Heike Elisabeth Daldrup-Link   +15 more
doaj   +1 more source

CD4⁺ T Cell-Mimicking Nanoparticles Broadly Neutralize HIV-1 and Suppress Viral Replication through Autophagy

mBio, 2020
Therapeutic strategies that provide effective and broad‐spectrum neutralization against HIV-1 infection are highly desirable. Here, we investigate the potential of nanoengineered CD4+ T cell membrane-coated nanoparticles (TNP) to neutralize a broad range
Gang Zhang, Grant R. Campbell, Qiangzhe Zhang, Erin Maule, Jonathan Hanna, Weiwei Gao, Liangfang Zhang, Stephen A. Spector   +7 more
doaj   +1 more source

Anti‐NMDA receptor autoimmune encephalitis associated with ovarian teratoma: A case series and literature review

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 23-30, April 2025.
Abstract Autoimmune encephalitis is a group of disorders characterized by symptoms of dysfunction of the limbic and extra‐limbic systems that occur in association with antibodies against intracellular antigens, synapses, or proteins located on the surface of nerve cells. Anti‐NMDA (N‐methyl‐D‐aspartate) receptor encephalitis was first described in 2007
Pham Ba Nha, Nguyen Phuong Tu, Nguyen Viet Ha, Duong Thi Thu Hien, Nguyen Thi Thu Phuong, Nguyen Anh Son, Nguyen Tien Hoang   +6 more
wiley   +1 more source

Ce qu’il reste de vivant : mémoire(s) du TNP [PDF]

, 2022
Il suffit de pousser les portes du TNP nouvellement rénové et de laisser errer son regard dans les couloirs du bâtiment pour comprendre que ce lieu de théâtre est aussi un lieu chargé d’Histoire.
Charlet, Émilie, Pellois, Anne
core   +1 more source

Polyglycolic Acid Polymer Versus Porcine Small Intestine Submucosa Graft After Plaque Incision in Peyronie's Disease: A Comparative Study

Andrology, EarlyView.
ABSTRACT Background Peyronie's disease (PD) with severe penile curvature often requires surgical correction through plaque incision and grafting (PIG). Objectives To compare surgical outcomes between polyglycolic acid polymer grafts and porcine small intestinal submucosa (SIS) grafts in patients undergoing PIG for PD.
Renan Trevisan Jost, Leonardo Seligra Lopes, Pedro Caetano Edler Zandoná, Jovânio Fernandes da Rosa, Pedro Fernandes Lessa, Felipe Placco Araujo Glina, Nívio Pascoal Teixeira, Sidney Glina   +7 more
wiley   +1 more source

Astigmatic changes after Descemet membrane endothelial keratoplasty (DMEK) in decompensated penetrating keratoplasty grafts

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate the surgery‐induced changes of astigmatism after Descemet membrane endothelial keratoplasty (DMEK) in eyes with failed previous penetrating keratoplasty (PK). Design Retrospective, interventional cohort study based on prospective DMEK database.
Florian Thomas Steinberg, Jithmi Weliwitage, Marie von Berg, Silvia Schrittenlocher, Simona Schlereth, Claus Cursiefen, Björn Bachmann   +6 more
wiley   +1 more source

Job satisfaction and perceived leadership behaviours among the Turkish national police department: A case study on Eskisehir police department [PDF]

, 2008
This research explores the management problems in the Turkish National Police Organisation (TNP) by assessing the perceived leadership behaviours and job satisfaction of police officers working at the Eskisehir Police Department in Turkey.
Yucel, Ali Bogachan
core