Results 51 to 60 of about 46,460 (216)

Multiple functional therapeutic effects of TnP: A small stable synthetic peptide derived from fish venom in a mouse model of multiple sclerosis.

open access: yesPLoS ONE, 2017
The pathological condition of multiple sclerosis (MS) relies on innate and adaptive immunity. New types of agents that beneficially modify the course of MS, stopping the progression and repairing the damage appear promising. Here, we studied TnP, a small
Evilin Naname Komegae   +4 more
doaj   +1 more source

Regional Differences in U.S. Consumer Preferences for Native Woody Shrubs With Varying Aesthetic Characteristics

open access: yesAgribusiness, EarlyView.
ABSTRACT Native plants offer a variety of aesthetic (e.g., fall colour, fruit, flowers) and functional benefits (e.g., pollinator friendly, wildlife friendly, water management). How these benefits influence consumer choice and perceived value of native versus introduced plants is not well understood.
Alicia Rihn   +3 more
wiley   +1 more source

Cyclophosphamide-sensitive contrasuppression in TNP-anterior chamber associated immune deviation (TNP-ACAID).

open access: yesThe Journal of Immunology, 1983
Abstract Injection of trinitrophenyl (TNP)-modified splenocytes (TNP-Sp) into the anterior chamber of the eye results in systemic tolerance to TNP, a phenomenon termed anterior chamber associated immune deviation (TNP-ACAID). Two distinct suppressor pathways develop after the induction of TNP-ACAID.
J C, Waldrep, H J, Kaplan
openaire   +4 more sources

Reduced basal ganglia μ-opioid receptor availability in trigeminal neuropathic pain: A pilot study

open access: yesMolecular Pain, 2012
Background Although neuroimaging techniques have provided insights into the function of brain regions involved in Trigeminal Neuropathic Pain (TNP) in humans, there is little understanding of the molecular mechanisms affected during the course of this ...
DosSantos Marcos   +9 more
doaj   +1 more source

Transparent and Multi‐Foldable Nanocellulose Paper Microsupercapacitors

open access: yesAdvanced Science, 2022
Despite the ever‐increasing demand for transparent power sources in wireless optoelectronics, most of them have still relied on synthetic chemicals, thus limiting their versatile applications.
Sang‐Woo Kim   +5 more
doaj   +1 more source

PRESISTANT: Learning based assistant for data pre-processing [PDF]

open access: yes, 2018
Data pre-processing is one of the most time consuming and relevant steps in a data analysis process (e.g., classification task). A given data pre-processing operator (e.g., transformation) can have positive, negative or zero impact on the final result of
Abelló, Alberto   +3 more
core   +2 more sources

TnP Peptide Suppresses Experimental Autoimmune Encephalomyelitis (EAE) in a Preclinical Mouse Model

open access: yesFrontiers in Immunology, 2022
TnP is a family of patented synthetic peptides which is in a preclinical development stage with valuable potential therapeutic indication for multiple sclerosis (MS), an autoimmune demyelinating disease of the central nervous system (CNS).
Carla Lima   +5 more
doaj   +1 more source

Message Authentication Code over a Wiretap Channel

open access: yes, 2015
Message Authentication Code (MAC) is a keyed function $f_K$ such that when Alice, who shares the secret $K$ with Bob, sends $f_K(M)$ to the latter, Bob will be assured of the integrity and authenticity of $M$.
Chen, Dajiang   +2 more
core   +1 more source

Sh3bp2 Gain-Of-Function Mutation Ameliorates Lupus Phenotypes in B6.MRL-Faslpr Mice [PDF]

open access: yes, 2019
SH3 domain-binding protein 2 (SH3BP2) is an adaptor protein that is predominantly expressed in immune cells, and it regulates intracellular signaling. We had previously reported that a gain-of-function mutation in SH3BP2 exacerbates inflammation and bone
Iseki, Masanori   +9 more
core   +1 more source

Multimodal Chromatography in the Downstream Processing of mAb‐Based Products: Mechanisms, Strategies, and Applications

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Multimodal chromatography has emerged as a powerful tool for the purification of monoclonal antibodies (mAbs) and their derivatives—including antibody fragments (Fabs), Fc‐fusions, bispecific (BsAb), and antibody–drug conjugates (ADCs)—offering enhanced selectivity through the integration of ionic, hydrophobic, hydrogen‐bonding, and π–π ...
Amin Javidanbardan   +4 more
wiley   +1 more source

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