Results 121 to 130 of about 106,112 (301)

Treatment of a large cohort of childhood chronic non‐infectious uveitis a multicentric large study: adalimumab versus methotrexate as first line therapy

Arthritis &Rheumatology, Accepted Article.
Background Treatment of childhood chronic idiopathic uveitis (cCIU) is predominantly based on studies in Juvenile Idiopathic Arthritis associated uveitis and expert opinion. Our aim was to report the treatment outcomes of our cohort of cCIU. Methods Retrospective multicenter study involving the rheuma/ophthalmology units at Florence and Bristol.
Ilaria Maccora, Catherine Guly, Cinzia de Libero, Giulia Carreras, Athimalaipet V. Ramanan, Gabriele Simonini   +5 more
wiley   +1 more source

The Clinical Value of Inflammatory Indicators at the Time of Secondary Infection After Treatment With Tocilizumab: A Cross‐Sectional Study

Health Science Reports
Background and Aims Tocilizumab, an anti‐inflammatory agent used in severe COVID‐19 infection, is known to inhibit the Interleukin 6 receptor and reduce C‐reactive protein (CRP) resulting in an increased risk of secondary infections.
Dena Firouzabadi, Amirreza Dehghanian, Sahar DehghanKhalili, Saeed DehghanKhalili, Seyed Mohammad Hosseini Saadi   +4 more
doaj   +1 more source

POS1200 IL-6 HIGHER LEVEL AFTER TOCILIZUMAB TREATMENT AS A PREDICTOR OF NOT-SURVIVAL IN COVID19 SEVERE PNEUMONIA: THE EXPERIENCE OF THE COVIBAS-STUDY [PDF]

, 2021
Michele Gilio, S. B. Morella, M. A. Purgatorio, Davide Palazzo, Maria Frontuto, A. Erezanu, G. Mastroberti, A. Linzalone, G Pietromatera, Anna Fineo, Mirella Onofrio, G. Casciano, G. De Stefano   +12 more
openalex   +1 more source

Rheumatoid arthritis and spondyloarthropathy [PDF]

, 2013
Part 2 of the article can be found through this link: https://www.um.edu.mt/library/oar//handle/123456789/13280Rheumatoid arthritis (RA) and spondyloarthropathy are two groups of inflammatory joint disease.
Vassallo, Pierre
core  

Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel, Christine van Linge, W. Joost Wiersinga, Ilse J. E. Kouijzer, Quirijn de Mast, Robert‐Jan Hassing, Danique J. H. Huijbens, Helen L. Leavis, Roger Schutgens, Coen Maas, Kit C. B. Roes, Frank L. van de Veerdonk, Roger Brüggemann   +12 more
wiley   +1 more source

Efficacy of Tocilizumab vs. NSAIDs in the Treatment of Juvenile Rheumatoid Arthritis

, 2022
Daniela I. Sánchez, Paola L. Padilla, Felix Osuna Gutierrez, Giancarlo T. Ornelasa, Flavio Humberto Ávalos   +4 more
openalex   +2 more sources

The clinical effectiveness and cost-effectiveness of abatacept, adalimumab, etanercept and tocilizumab for treating juvenile idiopathic arthritis: a systematic review and economic evaluation

, 2016
Background: Juvenile idiopathic arthritis (JIA) is characterised by joint pain, swelling and limitation of movement caused by inflammation. Subsequent joint damage can lead to disability and growth restriction.
Abbvie, Albarouni, All Wales Medicines Strategy Group, All Wales Medicines Strategy Group, All Wales Medicines Strategy Group, All Wales Medicines Strategy Group, Angeles-Han, Arthritis Care, Arthritis Care, Arthritis Care, Arthritis Care, Arthritis Research UK, Baildam, Baildam, Barton, Baszis, Bechtold, Berard, Bertilsson, Briggs, Briggs, Bristol-Myers Squibb, British Society for Paediatric and Adolescent Rheumatology, British Society for Paediatric and Adolescent Rheumatology, Brodszky, Brunner, Brunner, Brunner, Brunner, Brunner, Bruns, Bucher, Burgos-Vargas, Burgos-Vargas, Burgos-Vargas, Burgos-Vargas, Burgos-Vargas, Burgos-Vargas, Canadian Agency for Drugs and Technologies in Health, Chang, Chen, Connock, Consolaro, Consolaro, Consolaro, Consolaro, Cordero-Coma, Costa, Cummins, Cummins, Curtis, Dakin, De Benedetti, De Benedetti, Department of Health, Dias, Diaz-Llopis, Donegan, Drummond, Duffy, European Medicines Agency, European Medicines Agency, European Medicines Agency, European Medicines Agency, Feeny, Foeldvari, Gani, Garcia-De-Vicuna, Geikowski, Giannini, Glenny, Haapasaari, Heiligenhaus, Hendry, Higgins, Higgins, Horizon Scanning Centre, Horneff, Horneff, Imagawa, Joint Formulary Committee, Kearsley-Fleet, Kearsley-Fleet, Kemper, Khan, Kingsbury, Klein, Kuhlthau, Lloyd Jones, Lovell, Lovell, Lovell, Lovell, Lovell, Lovell, Lovell, Lovell, Luca, Luca, Lundkvist, Magli, Malottki, Martin, McErlane, McErlane, Mills, Minden, Minden, Monthly Index of Medical Specialties, Moorthy, National Institute for Health and Care Excellence, National Institute for Health and Care Excellence, National Institute for Health and Care Excellence, National Institute for Health and Care Excellence, National Rheumatoid Arthritis Society, National Rheumatoid Arthritis Society (NRAS), NHS England Clinical Reference Group for Paediatric Medicine, NHS England Specialised Services Clinical Reference Group for Specialised Ophthalmology, Nikolakopoulou, Office for National Statistics, Otten, Otten, Packham, Paediatric Formulary Committee, Parsons, Pennington, Petty, Pfizer Ltd, Philips, Prakken, Prince, Prince, Prince, Prince, Ramanan, Ravelli, Ravelli, Reeves, Riemsma, Rigante, Roche, Ruperto, Ruperto, Ruperto, Ruperto, Ruperto, Ruperto, Ruperto, Simonini, Simonini, Simpson, Simpson, Simpson, Smith, Sonnenberg, Stagi, Stevenson, Thierry, Thomson, Thornton, Tong, Tse, Tynjala, Ungar, Ungar, Vidqvist, Wallace, Wallace, Wallace, Yagudina, Zannin, Zeng   +171 more
core   +1 more source

Non‐Syndromic Tumefactive Demyelinating Lesions in the Pediatric Population: Four Case Reports and Review of the Literature

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Introduction Tumefactive demyelinating lesions (TDLs) are large lesions (> 2 cm) seen in demyelinating syndromes such as multiple sclerosis, myelin oligodendrocyte glycoprotein antibody‐associated disorder, and neuromyelitis optica spectrum disorder. They rarely occur in children and most often have a monophasic course.
Elizabeth C. Ballinger, Hannah F. Todd, Jonathan M. Yarimi, Timothy E. Lotze, Nikita M. Shukla, Kristen S. Fisher, Alexander J. Sandweiss   +6 more
wiley   +1 more source

Mortality risk stratification for Takotsubo syndrome: Evaluating CRP measurement alongside the InterTAK prognostic score

ESC Heart Failure, Volume 12, Issue 2, Page 1427-1436, April 2025.
Abstract Background and objectives Initially described as a benign acute cardiomyopathy, Takotsubo syndrome has been linked to elevated mortality rates. Emerging evidence suggests that unresolved myocardial inflammation may contribute to this adverse prognosis.
Loïc Faucher, Kensuke Matsushita, Shinnosuke Kikuchi, Taraneh Tatarcheh, Benjamin Marchandot, Amandine Granier, Said Amissi, Antonin Trimaille, Laurence Jesel, Patrick Ohlmann, Kiyoshi Hibi, Valérie Schini‐Kerth, Olivier Morel   +12 more
wiley   +1 more source

High Mortality Rate in Severe COVID-19 Despite Tocilizumab Administration: A Case Series

JKS (Jurnal Kedokteran Syiah Kuala)
Introduction: Tocilizumab is a potential therapeutic agent for modulating cytokine storms, a known cause of multiorgan failure and mortality in severe COVID-19.
Cokorda Agung Wahyu Purnamasidhi, Ida Bagus Yorky Brahmantya, Saktivi Harkitasari, I Gusti Ngurah Mahaalit Aribawa, I Ketut Agus Somia   +4 more
doaj   +1 more source