Results 71 to 80 of about 3,020 (217)

Combined uterorelaxant effect of magnesium sulfate and terbutaline: Studies on late pregnant rat uteri in vitro and in vivo

Acta Obstetricia et Gynecologica Scandinavica, 2023
Introduction Preterm delivery and its complications are among the biggest challenges and health risks in obstetrical practice. Several tocolytic agents are used in clinical practice, although the efficacy and side effect profiles of these drugs are not ...
Tamara Barna, Kalman F. Szucs, Annamaria Schaffer, Mohsen Mirdamadi, Judit Hajagos‐Toth, Robert Gaspar   +5 more
doaj   +1 more source

17-Hydroxyprogesterone caproate to prolong pregnancy after preterm rupture of the membranes: early termination of a double-blind, randomized clinical trial [PDF]

, 2011
Background Progestational agents may reduce the risk of preterm birth in women with various risk factors. We sought to test the hypothesis that a weekly dose of 17-hydroxyprogesterone caproate (17P) given to women with preterm rupture of the membranes ...
C Andrew Combs, Thomas J Garite, Kimberly Maurel, Kimberly Mallory, Rodney K Edwards, George Lu, Richard Porreco, Anita Das, null null   +8 more
core   +2 more sources

The Role of the Vaginal Microbiome in Preterm Premature Rupture of Membranes: A Comprehensive Review of Mechanisms and Clinical Implications

Health Science Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background and Aims Preterm premature rupture of membranes (PPROM), a complication in approximately 4.5% of pregnancies, is a leading cause of preterm birth and significant perinatal morbidity. A substantial body of evidence implicates vaginal dysbiosis a departure from a healthy, Lactobacillus‐dominant microbiome in the pathogenesis of PPROM.
Maryam Alikamali, Sakineh Mohammad‐Alizadeh‐Charandabi, Somayeh Ahmadi, Mohammad Yousef Memar, Mahnaz Shahnazi   +4 more
wiley   +1 more source

Antimicrobial prescribing guidelines for horses in Australia

Australian Veterinary Journal, Volume 103, Issue 12, Page 781-889, December 2025.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt, K Thomas, S Page, J Norris, G Browning, C El Hage, A Stewart, J Gilkerson, G Muscatello, D Verwilghen, G van Galen, J Bauquier, R Cuming, B Reynolds, C Whittaker, E Wilkes, J Clulow, C Burden, L Begg   +18 more
wiley   +1 more source

Gauging the safety and efficacy of nitroglycerine used transdermally as a tocolytic agent in females with preterm labor

Muller Journal of Medical Sciences and Research
Background: Preterm labor is the primary challenge in prenatal health care, leading to a high rate of mortality. As a result, in pregnant women with preterm labor, we use nitroglycerine transdermally as a tocolytic agent. The main objective of this study
Anand Tambat, Prashant Athawale, Chaitanya Deore   +2 more
doaj   +1 more source

Bryophyllum pinnatum enhances the inhibitory effect of atosiban and nifedipine on human myometrial contractility: an in vitro study

BMC Complementary and Alternative Medicine, 2019
Background The herbal medicine Bryophyllum pinnatum has been used as a tocolytic agent in anthroposophic medicine and, recently, in conventional settings alone or as an add-on medication with tocolytic agents such as atosiban or nifedipine.
S. Santos, C. Haslinger, M. Mennet, U. von Mandach, M. Hamburger, A. P. Simões-Wüst   +5 more
doaj   +1 more source

Contribution of chloride channels to the action potential and contraction in human myometrium during labour

British Journal of Pharmacology, Volume 182, Issue 23, Page 5748-5761, December 2025.
Background and purpose The action potential underpinning calcium delivery for contraction in human uterine smooth muscle (myometrium) consists of an initial spike(s) followed by a prolonged plateau of depolarization to ⁓ −25 mV. The plateau duration establishes contraction duration, especially important in labour.
Helena C. Parkington, Ranga E. Siriwardhana, Mary A. Tonta, Shaun P. Brennecke, Penelope M. Sheehan, Marianne Tare, Harold A. Coleman   +6 more
wiley   +1 more source

Apamin inhibits NO-induced relaxation of the spontaneous contractile activity of the myometrium from non-pregnant women

Reproductive Biology and Endocrinology, 2003
There is now considerable evidence for the involvement of K+ channels in nitric oxide (NO) induced relaxation of smooth muscles including the myometrium.
Kleszczewski Tomasz, Sipowicz Marek, Kostrzewska Anna, Modzelewska Beata, Batra Satish   +4 more
doaj   +1 more source

Executive summary: Workshop on preterm birth, January 28–29, 2025, co‐sponsored by the American College of Obstetricians and Gynecologists and the Eunice Kennedy Shriver National Institute of Child Health and Human Development

Pregnancy, Volume 1, Issue 6, November 2025.
Abstract The Society for Maternal‐Fetal Medicine collaborated with the American College of Obstetricians and Gynecologists and the Eunice Kennedy Shriver National Institute of Child Health and Human Development at the National Institutes of Health to co‐sponsor the annual SMFM President's Workshop on preterm birth.
Society for Maternal‐Fetal Medicine (SMFM), Rupsa Boelig, Andrea Edlow, Tracy Manuck, Eva Pajkrt, Ina A. Stelzer, Sarahn Wheeler, Cynthia Gyamfi‐Bannerman   +7 more
wiley   +1 more source

Use of Atosiban in a Twin Pregnancy With Extremely Preterm Premature Rupture in the Membrane of one Twin: A Case Report and Literature Review

Taiwanese Journal of Obstetrics & Gynecology, 2010
Objective: Pregnancies with extremely preterm premature rupture of membranes (EPPROM), especially before 20 weeks of gestation, are usually considered to be a termination of pregnancy.
Ming-Yih Wu, Shee-Uan Chen, Chien-Nan Lee, Hong-Nerng Ho, Yu-Shih Yang   +4 more
doaj   +1 more source