Results 131 to 140 of about 62,912 (312)

Autoantibody signatures in children with celiac disease, juvenile idiopathic arthritis, and polyautoimmunity

open access: yesJPGN Reports, EarlyView.
Abstract Objective To determine if multiplex autoantibody arrays can identify novel biomarker signatures in children with one or multiple autoimmune diseases (polyautoimmunity). Methods Plasma collected from children (18 years or younger) in the Boston Children's Hospital Precision Link Biobank for Health Discovery between January 2007 and June 2021 ...
Nan Du   +7 more
wiley   +1 more source

Unravelling the Major Cardiovascular Risks of Systemic Psoriasis Medications: A Literature Systematic Review

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Psoriasis is a chronic inflammatory dermatological condition associated with an elevated risk of cardiovascular events (CVEs). Systemic therapies have transformed disease management, but their cardiovascular (CV) safety profiles remain incompletely understood and inconsistently reported.
Mai Thi Hoai Son   +10 more
wiley   +1 more source

Tofacitinib inhibits ox-LDL-induced adhesion of THP-1 monocytes to endothelial cells

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2019
Atherosclerosis is a chronic inflammatory disease of the blood vasculature. Endothelial dysfunction is an early event in the development of atherosclerosis and the endothelium plays an important role in the innate immune defense in the pathology of ...
Xiaoyang Yang   +4 more
doaj   +1 more source

Dosing Biologic Drugs for Patients with Obesity: One Size Does NOT Fit All

open access: yes
Arthritis &Rheumatology, Accepted Article.
Stephen J. Balevic   +2 more
wiley   +1 more source

Characteristics of Adult Patients With Atopic Dermatitis Initiating Biologics and Janus Kinase Inhibitors in the CorEvitas Atopic Dermatitis Registry

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Biologics and Janus kinase inhibitors (JAKi) are two advanced systemic treatment options for patients with atopic dermatitis (AD). The decision to initiate one of these therapies is complex and may be driven by many factors.
Eric L. Simpson   +12 more
wiley   +1 more source

Interleukin-2 shapes the cytotoxic T cell proteome and immune environment sensing programs [PDF]

open access: yes, 2018
Proteomic analysis reveals how the cytokine IL-2 enables cytotoxic T cells to function and respond to their environment.
Brady, Hugh J. M.   +4 more
core   +2 more sources

Effectiveness and Safety of Tofacitinib in Canadian Patients With Rheumatoid Arthritis: Primary Results From a Prospective Observational Study [PDF]

open access: hybrid, 2022
Boulos Haraoui   +13 more
openalex   +1 more source

Successful Treatment of Paediatric Necrobiosis Lipoidica With Baricitinib

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Necrobiosis lipoidica (NL) is a rare, chronic granulomatous condition that typically presents as sharply demarcated plaques with telangiectasia and atrophic centres. Paediatric cases are uncommon, and treatment options often fail to address refractory cases.
P. Simões Farinha, M. J. Paiva‐Lopes
wiley   +1 more source

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