Virome of Terrestrial Mammals and Bats from Southern Brazil: Circulation of New Putative Members of the Togaviridae Family and Other Findings [PDF]
PathogensThe surveillance of wildlife viromes is essential for identifying zoonotic threats within the One Health framework. This study analyzed rectal and oral swabs from 88 individuals representing 13 species as felids, wild rodents, marsupials and non-human ...
Julyana Sthéfanie Simões Matos +8 more
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Insect-specific viruses: transmission dynamics and biological control strategies against arboviruses [PDF]
Frontiers in MicrobiologyMosquitoes are known to vector arthropod-borne viruses (arboviruses) that pose a global public health issue in the form of mosquito-borne viral diseases such as chikungunya fever, dengue fever, Japanese encephalitis, yellow fever, and Zika.
Lukas Wilkman +7 more
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Vaccine development for mosquito-borne viral diseases
Frontiers in Immunology, 2023 Mosquito-borne viral diseases are a group of viral illnesses that are predominantly transmitted by mosquitoes, including viruses from the Togaviridae and Flaviviridae families.
Zhiwei Huang +7 more
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Intervirology, 1985 The family Togaviridae comprises four genera: Alphavirus (with 26 species), Rubivirus (one species), Pestivirus (three species), and Arterivirus (one species). The main characteristics of the member viruses are: (i) the virus particles are spherical, 50-70 nm in diameter, including an envelope with surface projections that incorporate two or three ...
Horzinek, M.C. +9 more
openaire +3 more sources
An Unusual Case of Myelitis with Myositis [PDF]
Journal of Clinical and Diagnostic Research, 2016 The Chikungunya virus belonging to genus alphavirus and family togaviridae causes an arthropod-borne self-limiting febrile illness in humans. Neurological complications are rare with myelitis being even a rarer presentation.
Neera Choudhary +4 more
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Epidemic Alphaviruses: Ecology, Emergence and Outbreaks
Microorganisms, 2020 Over the past century, the emergence/reemergence of arthropod-borne zoonotic agents has been a growing public health concern. In particular, agents from the genus Alphavirus pose a significant risk to both animal and human health.
Sasha R. Azar +4 more
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Multiple interferon stimulated genes synergize with the zinc finger antiviral protein to mediate anti-alphavirus activity. [PDF]
PLoS ONE, 2012 The zinc finger antiviral protein (ZAP) is a host factor that mediates inhibition of viruses in the Filoviridae, Retroviridae and Togaviridae families.
Sophiya Karki +5 more
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A mini-review on sofosbuvir and daclatasvir treatment in coronavirus disease 2019
New Microbes and New Infections, 2021 Sofosbuvir and daclatasvir have been used successfully since 2013 for hepatitis C treatment. It has been shown by different studies that sofosbuvir can inhibit RNA polymerase of other positive-strand RNA viruses including Flaviviridae and Togaviridae ...
M. Shabani +3 more
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Complex antigen presentation pathway for an HLA-A*0201-restricted epitope from Chikungunya 6K protein. [PDF]
PLoS Neglected Tropical Diseases, 2017 The adaptive cytotoxic T lymphocyte (CTL)-mediated immune response is critical for clearance of many viral infections. These CTL recognize naturally processed short viral antigenic peptides bound to human leukocyte antigen (HLA) class I molecules on the ...
Elena Lorente +5 more
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Differential effects of lipid biosynthesis inhibitors on Zika and Semliki Forest viruses [PDF]
, 2017 The recent outbreak of infection with Zika virus (ZIKV; Flaviviridae) has attracted attention to this previously neglected mosquito-borne pathogen and the need for efficient therapies.
Donald, Claire L. +4 more
core +1 more source