Results 71 to 80 of about 10,675 (200)

The antiviral RNAi response in vector and non-vector cells against orthobunya viruses [PDF]

, 2017
Background: Vector arthropods control arbovirus replication and spread through antiviral innate immune responses including RNA interference (RNAi) pathways. Arbovirus infections have been shown to induce the exogenous small interfering RNA (siRNA) and
Bausch, DG, Blomström, AL, Dietrich, I, Elliott, RM, Kohl, A, McFarlane, M, Schnettler, E, Shi, X, Skelton, JK, Watson, M   +9 more
core   +5 more sources

Two Birds With One Stone: RNA Virus Strategies to Manipulate G3BP1 and Other Stress Granule Components

WIREs RNA, Volume 16, Issue 2, March/April 2025.
Stress granules emerging during viral infection can play both pro‐ and antiviral roles. RNA viruses use various strategies to antagonize their formation, including the degradation, inhibition, or sequestration of G3BP1, a key stress granule protein. However, biochemical and structural insights into these mechanisms have been reported for only a handful
Moh Egy Rahman Firdaus, Eliana Dukhno, Rupali Kapoor, Piotr Gerlach   +3 more
wiley   +1 more source

Seroprevalence of antibodies to Venezuelan equine encephalitis complex (subtypes IAB and VI) in humans from General Belgrano Island, Formosa, Argentina

Revista do Instituto de Medicina Tropical de São Paulo, 2003
This work presents the results of the detection of antibodies (immunoglobulin G) for subtypes I and VI of VEE viruses complex (Togaviridae family) in people from the General Belgrano island, Formosa province (Argentina).
Cámara Alicia, Díaz Gladis, Vega Victor, Basualdo María, Contigiani Marta   +4 more
doaj  

The possibly neglected victims: Re‐examining the involvement of children in the chikungunya epidemic

Pediatric Investigation, Volume 9, Issue 3, Page 234-240, September 2025.
Ran Wang, Kevin C. Kain, Zhengde Xie
wiley   +1 more source

Dysregulated ribosome quality control in human diseases

The FEBS Journal, Volume 292, Issue 5, Page 936-959, March 2025.
Ensuring the synthesis of full‐length, correctly folded proteins is vital for maintaining homeostasis. If a translating ribosome stalls, the trailing ribosomes collide into it, which if left unresolved leads to deleterious effects on the cell due to the accumulation of protein aggregates.
Tom McGirr, Okan Onar, Seyed Mehdi Jafarnejad   +2 more
wiley   +1 more source

The Mayaro virus and its potential epidemiological consequences in Colombia: an exploratory biomathematics analysis

Parasites & Vectors, 2020
Background Mayaro virus (Togaviridae) is an endemic arbovirus of the Americas with epidemiological similarities with the agents of other more prominent diseases such as dengue (Flaviviridae), Zika (Flaviviridae), and chikungunya (Togaviridae).
Bryan Steven Valencia-Marín, Irene Duarte Gandica, Oscar Alexander Aguirre-Obando   +2 more
doaj   +1 more source

RNA interference targets arbovirus replication in Culicoides cells [PDF]

, 2013
This work was supported by United Kingdom Medical Research Council and Wellcome Trust.Arboviruses are transmitted to vertebrate hosts by biting arthropod vectors such as mosquitoes, ticks, and midges.
Elliott, Richard M., Kohl, Alain, McFarlane, Melanie, Palmarini, Massimo, Ratinier, Maxime, Schnettler, Esther, Shaw, Andrew E., Varela, Mariana, Watson, Mick   +8 more
core   +2 more sources

Microbiological Investigations for Chikungunya Virus in Children With Acute Encephalitis Syndrome in a Non‐Outbreak Setting in Southern India

Journal of Medical Virology, Volume 97, Issue 2, February 2025.
ABSTRACT Chikungunya virus (CHIKV) is an emerging cause of acute encephalitis syndrome (AES) in India, with limited data on its role in childhood AES in southern India. We systematically evaluated children with AES in southern India during a non‐epidemic period for CHIKV. Serum and cerebrospinal fluid (CSF) samples were tested for CHIKV using IgM ELISA
Tina Damodar, Chitra Pattabiraman, Bhagteshwar Singh, Maria Jose, Namratha Prabhu, Akhila L, Pramada Prasad, Uddhava V. Kinhal, A. V. Lalitha, Fulton Sebastian Dsouza, Sushma Veeranna Sajjan, Vykuntaraju K. Gowda, Vasanthapuram Ravi, Ruwanthi Kolamunnage‐Dona, Benedict D. Michael, Tom Solomon, Ravi Yadav, Lance Turtle   +17 more
wiley   +1 more source

The Journey of in vivo Virus Engineered Dendritic Cells From Bench to Bedside: A Bumpy Road

Frontiers in Immunology, 2018
Dendritic cells (DCs) are recognized as highly potent antigen-presenting cells that are able to stimulate cytotoxic T lymphocyte (CTL) responses with antitumor activity.
Cleo Goyvaerts, Karine Breckpot
doaj   +1 more source

Multiorgan proteomic analysis of infected animal models predict potential host factors for chikungunya virus

MedComm, Volume 6, Issue 1, January 2025.
We depicted the multiorgan proteomic landscape in CHIKV‐infected animal models, revealing the potential role of the RLR signaling pathway against CHIKV infection and dysregulated metabolism. Moreover, we predicted potential host factors contributing to organ‐specific inflammation and hemorrhage in rhesus monkeys through bioinformatic and correlation ...
Dongdong Lin, Cong Tang, Junbin Wang, Yun Yang, Hao Yang, Yanan Zhou, Wenhai Yu, Bai Li, Qing Huang, Haixuan Wang, Ran An, Xiaoming Liang, Yuhuan Yan, Longhai Yuan, Xuena Du, Yuxia Yuan, Yanwen Li, Shuaiyao Lu   +17 more
wiley   +1 more source