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A novel cabozantinib formulation with improved safety and bioavailability: preclinical validation in rats. [PDF]
Cancer Chemother PharmacolQin S +4 more
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A Single-Center, Open-Label Study to Evaluate the Efficacy and Tolerability of Retinal Encapsulated in a Novel Biomimetic Exosome in the Treatment of Mild-To-Moderate Facial Photodamage. [PDF]
J Cosmet DermatolGold MH +9 more
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Rapid tolerance and cross-tolerance as predictors of chronic tolerance and cross-tolerance
Pharmacology Biochemistry and Behavior, 1992Hypothermia and motor impairment (tilt-plane) tests were used to assess the phenomenon of rapid tolerance to ethanol and cross-tolerance to various alcohols, benzodiazepines, and barbiturates that differ in lipid:water partition coefficients. The hypothermic and motor impairment responses to ethanol were significantly reduced on day 2 in rats receiving
J M, Khanna +3 more
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Drugs, 2003
The excellent tolerability of therapeutic doses of paracetamol (acetaminophen) is a major factor in the very wide use of the drug. The major problem in the use of paracetamol is its hepatotoxicity after an overdose. Hepatotoxicity has also been reported after therapeutic doses, but critical analysis indicates that most patients with alleged toxicity ...
Garry G, Graham +2 more
openaire +3 more sources
The excellent tolerability of therapeutic doses of paracetamol (acetaminophen) is a major factor in the very wide use of the drug. The major problem in the use of paracetamol is its hepatotoxicity after an overdose. Hepatotoxicity has also been reported after therapeutic doses, but critical analysis indicates that most patients with alleged toxicity ...
Garry G, Graham +2 more
openaire +3 more sources