Annals of Gastroenterological Surgery, EarlyView.This systematic review and meta‐analysis evaluated the role of primary tumor resection (PTR) in asymptomatic patients with unresectable metastatic colorectal cancer. Across 17 eligible studies including 9317 patients, PTR did not improve overall or progression‐free survival compared with chemotherapy alone.
Junpei Takashima +3 more
wiley +1 more source
ACHTSAM study protocol: outreach diagnostics and assessment of tolerability in severe ME/CFS-a pilot study. [PDF]
BMJ OpenFricke C +5 more
europepmc +1 more source
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Background Although NCCN guidelines recommend preoperative therapy for borderline resectable pancreatic cancer (BR‐PC), it is still unclear which regimen is better. The study objective was to elucidate the prognostic significance of neoadjuvant chemoradiotherapy (NACRT) with gemcitabine/nab‐paclitaxel (GnP‐RT) compared to gemcitabine alone ...
Hirofumi Akita +9 more
wiley +1 more source
Comparative Efficacy and Safety of Glucagon Receptor Agonists on Metabolic Outcomes: A Network Meta-Analysis of Randomised Controlled Trials. [PDF]
Endocrinol Diabetes MetabAbulehia A +9 more
europepmc +1 more source
A Computational Approach for Biomimetic Design of Liver‐On‐A‐Chip
Advanced Intelligent Discovery, EarlyView.A biomimetic liver‐on‐a‐chip with antiparallel perfusion was designed using COMSOL‐guided simulation to replicate hepatic acinus transport. Full‐scale modelling revealed diffusion‐dominated, length‐dependent nutrient gradients and low‐shear conditions.
Zhenxu Yang +9 more
wiley +1 more source
Personalized Approach for Acne Management With Dermocosmetics According to Initial Skin Sensitivity. [PDF]
J Cosmet DermatolHan JH +9 more
europepmc +1 more source
Harnessing Phase Dynamics Across Diverse Frequencies with Multifrequency Oscillatory Neural Networks
Advanced Intelligent Discovery, EarlyView.Oscillatory Neural Networks (ONNs) are an emerging computing paradigm that encodes information in the phases of coupled oscillators. Traditionally, ONNs have been investigated using homogeneous frequency oscillators. However, physical hardware implementations are inherently subject to frequency mismatches, device variability, and nonuniformities.
Nil Dinç +2 more
wiley +1 more source
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.The systematic design of memristor‐based neural network is provided by analog conductance state parameters to accurately emulate the software‐based high‐resolution weight at discrete device level. The requirement of discrete analog conductance of memristor device is measured as ≈50 states with nonlinearity value of ≈0.142 within the deviation range of ...
Jingon Jang, Yoonseok Song, Sungjun Park
wiley +1 more source
Impact of authoritative and subjective cues on large language model reliability for clinical inquiries: an experimental study. [PDF]
Sci RepChang Y, Ju PC, Hsieh MH, Chang CC.
europepmc +1 more source
Methods for Setting Device Specifications for Analog In‐Memory Computing Inference
Advanced Intelligent Systems, EarlyView.Non‐volatile memories (NVMs) are being developed for analog in‐memory computing for energy‐efficient, high‐speed deep learning inference. As technology is moving to industry adoption, a method to define required NVM specifications is critical for improving performance and reducing manufacturing cost.
Zhenyu Wu +3 more
wiley +1 more source