Nonparametric Estimation, III. Statistically Equivalent Blocks and Multivariate Tolerance Regions--The Discontinuous Case [PDF]
John W. Tukey
openalex +1 more source
ABSTRACT Objective Music interventions have been shown to have beneficial effects on hemodynamic parameters, pain, and anxiety in various medical settings. However, music interventions in the setting of acute stroke have not been studied. The objective of this trial was to perform a pilot feasibility study of music interventions in the setting of acute
Jeffrey J. Fletcher+7 more
wiley +1 more source
Life on the dry side: a roadmap to understanding desiccation tolerance and accelerating translational applications. [PDF]
Marks RA+38 more
europepmc +1 more source
Phase 1, First‐In‐Human, Single‐/Multiple‐Ascending Dose Study of Iluzanebart in Healthy Volunteers
ABSTRACT Objective To evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of iluzanebart, a fully human monoclonal antibody TREM2 (triggering receptor expressed on myeloid cells 2) agonist, after single‐ (SAD) and multiple‐ascending‐dose (MAD) administration.
Andreas Meier+8 more
wiley +1 more source
COMPARATIVE VALUE OF BROMSULPHALEIN, SERUM PHOSPHATASE, PROTHROMBIN TIME, AND INTRAVENOUS GALACTOSE TOLERANCE TESTS IN DETECTING HEPATIC DAMAGE PRODUCED BY CARBON TETRACHLORIDE [PDF]
Victor A. Drill, A. C. Ivy
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Combination Therapy With Vigabatrin and Prednisolone Versus Vigabatrin Alone for Infantile Spasms
ABSTRACT Objective The study evaluated the effectiveness of combination therapy with vigabatrin and prednisolone versus vigabatrin alone for treating infantile epileptic spasms syndrome (IESS). Methods This single‐center, single‐blind, randomized trial enrolled infants aged 2–14 months with new‐onset IESS, randomly assigned them (1:1) to receive either
Rachata Boonkrongsak+6 more
wiley +1 more source
Leaf drought and heat tolerance are integrated across three temperate biome types. [PDF]
Mitchell D+3 more
europepmc +1 more source
Home‐Based Tele‐tDCS in Amyotrophic Lateral Sclerosis: Feasibility, Safety, and Preliminary Efficacy
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with limited treatment options. Transcranial direct current stimulation (tDCS) shows promise as a neuromodulatory intervention in various neurological disorders, but its application in ALS, particularly in a remote, home‐based format, remains underexplored.
Sangeetha Madhavan+6 more
wiley +1 more source
NETs activate the GAS6-AXL-NLRP3 axis in macrophages to drive morphine tolerance. [PDF]
Tian Q+10 more
europepmc +1 more source